期刊
TETRAHEDRON LETTERS
卷 55, 期 38, 页码 5236-5240出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.08.002
关键词
1,4-Dihydropyridines; On-water synthesis; Magnetically recovered heterogeneous catalyst; Fe3O4@SiO2 nanoparticles; One-pot multi-component reaction
资金
- DST-India [SERC/F/0293/2012-13]
- DST-Purse-India
- NEHU-Non-NET fellowship
- UGC
An 'on-water', efficient, high yielding, expeditious method has been developed for the synthesis of 1,4-dihydropyridine (1,4-DHP) derivatives via an one-pot multi-component condensation of dimedone or 4-hydroxycoumarine, aldehydes, and ammonium acetate using Fe3O4@SiO2 nanoparticles as a recyclable heterogeneous catalyst. This method takes advantage of the fact that water, a green solvent is used in combination with Fe3O4@SiO2 nanoparticles as catalyst which can be easily recovered magnetically and reused for further runs. (C) 2014 Elsevier Ltd. All rights reserved.
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