Article
Chemistry, Organic
Peng-Fei Dai, Yi-Ping Wang, Jian-Ping Qu, Yan-Biao Kang
Summary: A synthetically practical transition metal/catalyst/halogen-free dehydrogenative coupling of aldehydes with N-hydroxyimides solely promoted by tert-butyl nitrite under mild conditions was developed. A diverse array of N-hydroxyimide esters can be prepared from either aliphatic or aromatic aldehydes, with benzoyl-substituted aldehydes also being suitable.
Article
Chemistry, Analytical
Xin Zhang, Xianghui Shi, Yong Pan, Juncheng Jiang
Summary: This study investigates the pyrolysis behavior of tert-butyl hydroperoxide (TBHP) through molecular dynamics simulations. The main pyrolysis products and reaction pathways are identified, and a detailed reaction mechanism is proposed. The calculated apparent activation energy agrees reasonably with experimental results. This research provides scientific guidance for the process safety of organic peroxides and the development of suppression technologies.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2022)
Article
Chemistry, Organic
Zhang Yunqian, Zhou Chenfan, Liu Gongqing
Summary: Phosphoroselenoates are widely used in organic synthesis and drug discovery. This study developed a new method for the synthesis of phosphoroselenoates through the oxidative coupling reaction of diselenides with phosphites using t-butyl hydroperoxide (TBHP) as an oxidant. The advantages of this method include mild reaction conditions, broad substrate scope, excellent yields, and the absence of transition metals and bases.
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Thermodynamics
Wenlin Huang, Congjie Hong, Wuchuan Sun, Honghuan Wu, Zuohua Huang, Yingjia Zhang
Summary: In this study, tert-butyl hydroperoxide (TBHP) was investigated as an additive reactively enhancer to improve the auto-ignition of n-heptane. The results showed a nonlinear promotion effect of TBHP on the auto-ignition of n-heptane, with detonation caused by TBHP impacting the reflected shock temperature and pressure at high beginning temperatures. Addition of TBHP suppressed the negative temperature coefficient (NTC) behavior of first-stage ignition and strengthened the NTC behavior of ignition delay time (IDT). Analysis indicated that TBHP facilitated the quick production of OH and CH3 radicals, enhancing the reactivity of n-heptane and affecting the main exothermic reaction in the early period. This study highlights the potential of TBHP in regulating the combustion of hydrocarbon fuels and provides insights for efficient utilization in scramjet engines and micro internal combustion engines.
COMBUSTION AND FLAME
(2023)
Article
Microbiology
Shih-Jie Chen, Hung-Yu Shu, Guang-Huey Lin
Summary: This study showed that Acinetobacter baumannii ATCC 19606 harbors two sets of ohrR-ohr genes in chromosomal DNA and a pMAC plasmid. While the chromosomal ohrR-C-ohr-C genes act as the major system in protecting the bacteria from organic hydroperoxide stresses, the pMAC ohrR-p-ohr-p genes can provide a supplementary protective effect and their interaction may influence bacterial growth and virulence.
Article
Chemistry, Organic
Qin Yang, Zhe Wang, Terumasa Kato, Yan Liu, Keiji Maruoka
Summary: Alkyl tert-butyl peroxides are synthesized from their corresponding tert-alkyl precursors and tert-butyl hydroperoxide with the aid of a promoter. These peroxides can be used in a copper-catalyzed radical functionalization, which involves coupling with various partners and exhibits broad substrate compatibility. Mechanistic investigations suggest the involvement of alkyl radical species in the coupling reactions.
Article
Chemistry, Physical
Julia Bueker, Martin Muhler, Baoxiang Peng
Summary: This concept article provides a comprehensive overview of recent advances in selective oxidation of cyclohexene using heterogeneous transition metal-based catalysts and environmentally benign oxidants.
Article
Chemistry, Organic
Kun Liu, Xuexue Chang, Yimiao He, Zhongfu Su, Yanmin Huang, Chusheng Huang, Jian Lei, Qiang Zhu
Summary: A tunable synthesis of chalcophosphinic amides and phosphinates was achieved through a copper-catalyzed reaction. The tert-butyl N,N-dialkylperoxyamidate played a dual role in this transformation without requiring additional oxidants, bases, or additives. The products were obtained under different catalytic conditions, offering a new approach to difficult-to-access compounds.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Biochemistry & Molecular Biology
Woo Kwon Jung, Su-Bin Park, Hwa Young Yu, Yong Hwan Kim, Junghyun Kim
Summary: Esculetin, derived from coumarin, has been found to have antioxidant and anti-apoptotic effects. It improves cell viability and reduces apoptosis in HEK293 cells under t-BHP-induced oxidative stress. At the molecular level, esculetin regulates the expression of pro-apoptotic and anti-apoptotic factors.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2022)
Article
Medicine, Research & Experimental
Qifeng Ren, Wenfei Zhang, Ping Li, Jianli Zhou, Zhonghao Li, Yang Zhou, Ming Li
Summary: Necrosis of the femoral head (NFH) is an orthopedic disease associated with inadequate blood supply and increased intraosseous pressure. The present study revealed that the expression of osteoprotegerin (OPG) was significantly decreased in the femoral head of NFH patients, and overexpression of OPG reversed chondrocyte apoptosis induced by oxidative stress.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Jordi Hug Badia, Carles Fite, Roger Bringue, Eliana Ramirez, Montserrat Iborra
Summary: The kinetics of BTBE synthesis over Amberlyst (TM) 35 catalyst was studied, revealing a kinetic model consistent with an Eley-Rideal mechanism where 1-butanol molecule adsorbs on an active site, reacts with isobutene to form BTBE molecule, with the surface reaction being the rate-determining step. The catalyst activity is influenced by the interaction between resin and reaction medium.
REACTION CHEMISTRY & ENGINEERING
(2021)
Article
Engineering, Environmental
Ning Li, Mengzhen Yuan, Guoju Cui, Jiale Xu, Xiuyi Li, Guowei Wang, Xiaolin Zhu, Chunyi Li
Summary: This study proposes a novel route using molecular oxygen for the green synthesis of di-tert-butyl peroxide (DTBP) from isobutane. MoO3 was demonstrated as the selective catalyst for this reaction, and the selectivity to DTBP was determined by the amount of surface Mo = O sites. Under optimized conditions, high oxygen conversion (>95%) and stable product selectivities (DTBP -20 wt%, TBHP -13 wt%) were achieved. This work provides an environmentally friendly method for utilizing C4 hydrocarbon resources and producing DTBP.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Jeremy Bourgalais, Zhongming Jiang, Julien Bloino, Olivier Herbinet, Hans-Heinrich Carstensen, Gustavo A. Garcia, Philippe Arnoux, Luc-Sy Tran, Guillaume Vanhove, Laurent Nahon, Frederique Battin-Leclerc, Majdi Hochlaf
Summary: This study presents a combined theoretical and experimental investigation on the synchrotron-based VUV single photon ionization of gas-phase tBuOOH. The ionization energy of tBuOOH and the appearance energy of important fragment ions were estimated. The results are significant for accurately quantifying tBuOOH in gas-phase oxidation/combustion experiments using advanced mass spectrometry techniques.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Physical
Bolatbek Khussain, Alexandr Brodskiy, Alexandr Sass, Kenzhegul Rakhmetova, Vladimir Yaskevich, Valentina Grigor'eva, Altay Ishmukhamedov, Anatoliy Shapovalov, Irina Shlygina, Svetlana Tungatarova, Atabek Khussain
Summary: The catalytically active vanadium-containing system on gamma-Al2O3 was studied using various physical and chemical methods. The system was found to include different complexes with varying thermal stabilities and catalytic activities. Active complexes based on V2O5 oxide are formed as the temperature of heat treatment increases, suggesting V2O5 oxide plays a crucial role in the catalytic activity. The vanadium-containing catalytic system on aluminium oxide was shown to be thermally stable and highly active in both the reduction of nitrogen oxides and the oxidation of hydrocarbons, making it promising for applications in exhaust gas purification and understanding catalyst mechanisms in decarbonization processes.
Article
Chemistry, Organic
Denisa Hidasova, Tomas Slanina
Summary: We present a mild OtBu deprotection catalytic protocol using two commercial reagents: magic blue (MB center dot+), also known as tris-4-bromophenylamminium radical cation, and triethylsilane. Magic blue catalytically facilitates the cleavage of the C-O bond in tert-butyl carbamates, carbonates, esters, and ethers, achieving a high isolated yield of up to 95%, while sacrificial triethylsilane accelerates the reaction. This method is suitable for an array of structurally diverse compounds without the need for high temperatures, transition metals, or strong acidic or basic catalysts.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Debasish Sarmah, Rakhee Saikia, Utpal Bora
Summary: The development of Chan-Lam cross-coupling technology provides a convenient method for the formation of C-N and C-S bonds. By using arylboronic acids as arylating agents, the need for expensive metal catalysts and high temperature reaction conditions is eliminated. Nickel has emerged as an inexpensive alternative with lower energy barriers for Chan-Lam cross-coupling, and exploring more alternatives is important for efficient C-X bond formation. This method can also be applied to the synthesis of pharmaceutically active scaffolds.
Article
Green & Sustainable Science & Technology
Niran Daimary, Pankaj Boruah, Khalifa S. H. Eldiehy, Tapan Pegu, Pritam Bardhan, Utpal Bora, Manabendra Mandal, Dhanapati Deka
Summary: This study focuses on transforming fruit and kitchen wastes into fuel through the synthesis of a catalyst, achieving the vision of a green, renewable, and sustainable integrated route. The research found that the biochar obtained from banana peel thermochemical conversion can be calcined and used as a catalyst for converting waste cooking oil into biodiesel, with a conversion rate of up to 98.0%.
Article
Multidisciplinary Sciences
Debajyoti Kabiraj, Hasnahana Chetia, Adhiraj Nath, Pragya Sharma, Ponnala Vimal Mosahari, Deepika Singh, Palash Dutta, Kartik Neog, Utpal Bora
Summary: This study presents the first complete mitogenome of Blepharipa sp., a dipteran parasitoid of Muga silkworm. The research confirms the similarity of Blepharipa sp. mitogenome gene content and arrangement to other Tachinidae and Sarcophagidae flies. It also reveals a higher AT content and AT biased codons in the Tachinidae mitogenomes, indicating a preference for AT-rich genes. The study suggests that natural selection plays a stronger role in codon usage bias than mutational pressure.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Niran Daimary, Khalifa S. H. Eldiehy, Neelam Bora, Pankaj Boruah, Muzamil Ahmad Rather, Manabendra Mandal, Utpal Bora, Dhanapati Deka
Summary: This study explores an integrated approach for transforming bio-waste and valorizing its byproducts. Banana pseudostem-derived biochar was used to synthesize a heterogeneous catalyst, while the ash was employed directly as a catalyst for biodiesel production. Additionally, an alkaline solution obtained from the ash was utilized for lignin recovery from bamboo leaves. Various characterization techniques were employed, and response surface methodology was used for optimization. The study demonstrates an inexpensive, sustainable, and environmentally friendly pathway for bio-waste valorization.
Article
Chemistry, Multidisciplinary
Dipika Konwar, Porag Bora, Bolin Chetia, Utpal Bora
Summary: The C-2 selective direct functionalization of N-methylindole derivatives with aryl iodides catalyzed by Pd supported on carbon has been developed. The method offers high selectivity, recyclability, and applicability to a wide range of substrates.
Article
Food Science & Technology
Jon Jyoti Kalita, Pragya Sharma, Utpal Bora
Summary: Food safety is a crucial concern due to the presence of contaminants that can have harmful effects on food. Oligonucleotide aptamers have emerged as a promising alternative to antibodies in the analysis of food contaminants, and various design strategies have led to disruptive innovations in this field.
Article
Chemistry, Multidisciplinary
Prantika Bhattacharjee, Anindita Dewan, Purna K. Boruah, Manash R. Das, Utpal Bora
Summary: This study presents a green and rapid assessment of lignocellulosic nanomaterials derived from waste fibrous feedstock of pomegranate peels. The use of lignocellulose as a support material for Pd nanoparticles enables the catalytic C2-H arylation of indoles with arylboronic acids with high regioselectivity and reusability. The catalyst also shows good functionality tolerance for free N-H indole moieties and can be used for selective double-functionalization of indole frameworks in a one-pot system.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Article
Chemistry, Organic
Dipika Konwar, Pranamika Sarma, Jagat Chandra Borah, Utpal Bora
Summary: Halogen bonding triggered by the Lewis basic nature of acetonitrile enables the site-selective C-3 triaryl methylation of indoles and N-triaryl methylation of imidazoles with trityl chlorides. The reaction proceeds under catalyst-, metal-, and additive-free conditions at room temperature. The method provides a quaternary carbon centre appended to a heterocyclic moiety and is applicable to a wide range of substrates, yielding moderate to excellent product yields (up to 100%) under ambient reaction conditions. Equimolar amounts of reactants are sufficient to obtain the optimum yield, and in some cases, pure products can be obtained without column chromatography.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Rakhee Saikia, Sanghamitra Das, Arzu Almin, Abhijit Mahanta, Bipul Sarma, Ashim J. Thakur, Utpal Bora
Summary: In this study, N,N'-Dimethylurea (DMU) is introduced as a ligand to aid the Chan-Lam N-arylation reaction. The method involves copper catalysis and in situ complexation of DMU with copper, resulting in the efficient synthesis of N-arylated anilines, 3-aminophenols, and primary amides in moderate to good yields (50-90%). The developed catalytic system extends the scope of N,N'-Dimethylurea as an auxiliary in inexpensive and versatile copper catalysis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Prantika Bhattacharjee, Bipul Sarma, Utpal Bora
Summary: A molecular-iodine catalyzed cascade addition/intramolecular cyclization reaction has been used to access an important class of bio-relevant indole derivatives, cyclopenta[b]indoles. The reaction's substrate control is essential, with the high-density electronic core of indole favoring the formation of indolyl-cyclopenta[b]indole derivatives.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Dipika Konwar, Rakhee Saikia, Risha Kalita, Manash R. Das, Utpal Bora
Summary: A biogenically synthesized Pd nanoparticle-decorated graphitic carbon nitride oxide sheet was developed for efficient Suzuki-Miyaura cross-coupling reactions. The catalyst not only functioned as a catalyst, but also served as a base, reducing the need for exogenous base. Furthermore, the catalyst exhibited good activity and could be easily recovered and reused.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Prantika Bhattacharjee, Anindita Dewan, Purna K. Boruah, Manash R. Das, Sanjeev P. Mahanta, Ashim J. Thakur, Utpal Bora
Summary: Cellulose fibers were extracted from waste pomegranate peels using a simple filtration method, and served as a bio-template for the formation of Pd-Ag bimetallic nanoclusters. The resulting heterogeneous catalyst exhibited enhanced catalytic activity, stability, and recyclability for Suzuki-Miyaura coupling of nitrogen-rich heterocycles under visible light conditions. The synergistic interactions between the bimetallic centers were responsible for the improved performance, facilitated by a localized surface plasmon resonance effect. The low energy input of the process also suggests its potential for large-scale nano-material production.
Meeting Abstract
Psychiatry
Puja Bora, Utpal Bora
INDIAN JOURNAL OF PSYCHIATRY
(2022)
Article
Chemistry, Multidisciplinary
Porag Bora, Dipika Konwar, Anindita Dewan, Manash R. Das, Utpal Bora
Summary: In this study, direct C-H bond functionalization of cyclic ethers through decarboxylation was achieved using synthesized biogenic CuO nanocatalysts under mild conditions. The method demonstrated a wide substrate scope with high yields and proceeded via a radical mechanism.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Engineering, Environmental
Niran Daimary, Khalifa S. H. Eldiehy, Pankaj Boruah, Dhanapati Deka, Utpal Bora, Biraj Kumar Kakati
Summary: The sustainable processing approach was used to transform potato peel into bio-oil and green heterogeneous catalysts. The byproduct, biochar, was reused as a renewable and sustainable catalyst source. The synthesized catalyst showed high catalytic activity and oil conversion rate.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)