期刊
TETRAHEDRON LETTERS
卷 54, 期 1, 页码 15-20出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.09.112
关键词
Cross-coupling; Diarylmethanes; Palladium catalysis; Heterocycles
资金
- National Science Foundation [NSF-GOALI 0848460]
A palladium-catalyzed cross coupling of nitrogen bearing heterocyclic chloromethyl derivatives with aryl and heteroaryl boronic acids has been developed. In almost all cases, highly efficient cross-couplings were observed at ambient temperature, mitigating unwanted thermally induced side-reactions. The comprehensive substrate scope and respectable yields highlight the synthetic utility of this reaction. (C) 2012 Elsevier Ltd. All rights reserved.
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