4.4 Article

Amberlite IR-120H as an efficient and versatile solid phase catalyst for nucleophilic substitution of propargylic alcohols

期刊

TETRAHEDRON LETTERS
卷 54, 期 27, 页码 3550-3553

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.04.120

关键词

Amberlite IR-120H; Nucleophilic substitution; Propargylic alcohols; Solid phase catalyst; Regioselectivity

资金

  1. College of Pharmacy of University of Arkansas for Medical Sciences

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A highly efficient Amberlite IR-120H resin mediated nucleophilic substitution of the hydroxyl group of propargylic alcohols with a wide range of nucleophiles is reported. The reactions were achieved under very mild conditions in excellent yields. (c) 2013 Elsevier Ltd. All rights reserved.

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