4.4 Article

I2/TBHP-mediated reaction of sulfonylhydrazides with alkynes: synthesis of (E)-β-iodovinyl sulfones

期刊

TETRAHEDRON LETTERS
卷 54, 期 24, 页码 3071-3074

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.03.117

关键词

(E)-beta-iodovinyl sulfones; Sulfonylhydrazides; TBHP; Sulfonyl radicals; Atom economy

资金

  1. National Science Foundation of China [21102130]
  2. Key Innovation Team of Science & Technology in Zhejiang Province [2010R50018, 2011R50017]

向作者/读者索取更多资源

An efficient and simple procedure for the syntheses of (E)-beta-iodovinyl sulfones through TBHP mediated reaction of sulfonylhydrazides and iodine with aryl acetylenes has been developed. This method offers several advantages such as high atom economy, environmentally benign oxidant, less byproduct, and easy operation. (C) 2013 Elsevier Ltd. All rights reserved.

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