Article
Chemistry, Multidisciplinary
Aleksandra Sarwa, Agata Bialonska, Mateusz Garbicz, Bartosz Szyszko
Summary: Depending on the size and basicity of the anion, the self-assembly of 2,5-diformylpyrrole, tris(2-aminoethyl)amine, and silver(I) resulted in new cascade complexes or plenates, which are cryptates incorporating Ag-n(n+) clusters. The nature of the product was determined by the counterion and its formation was driven by either cascade anion binding or argentophilic interactions stabilizing the cluster within the cavity. The reaction of plenates with tetrabutylammonium halides led to the protonation-coupled replacement of the Ag-3(3+) with anion(s), forming cascade cryptates.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Maria Diz, Maria L. Duran-Carril, Jesus Castro, Samuel Alvo, Lucia Bada, Dolores Vina, Jose A. Garcia-Vazquez
Summary: In this study, the electrochemical oxidation of copper metal was used to synthesize a series of homoleptic and solvate copper complexes with different ligands. These complexes exhibited significant cytotoxic activity against neuroblastoma and glioblastoma cell lines, surpassing the efficacy of the commonly used anticancer drug cisplatin. The mechanism of cell death induced by these complexes was also investigated.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Sarah C. Bete, Leander K. May, Philipp Woite, Michael Roemelt, Matthias Otte
Summary: In this study, a cage ligand providing a biomimetic environment was synthesized, in which copper can adopt different coordination modes. The copper(I) state reacts with dioxygen and undergoes CH activation. Additionally, the ligand exhibits catalytic performance similar to the oxidation of ubiquinol mimics.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Medicinal
Jingmin Cui, Yan Sun, Linqing Wang, Qin Miao, Wenqiang Tan, Zhanyong Guo
Summary: A series of l-arginine Schiff base acylated chitosan derivatives were successfully prepared to enhance the antioxidant and antimicrobial activities. Some compounds showed promising activities, indicating potential for further development and utilization as antioxidants and antimicrobial agents.
Review
Chemistry, Inorganic & Nuclear
Cherifa Boulechfar, Hana Ferkous, Amel Delimi, Amel Djedouani, Abdesalem Kahlouche, Abir Boublia, Ahmad S. Darwish, Tarek Lemaoui, Rajesh Verma, Yacine Benguerba
Summary: Schiff base metallic complexes have garnered considerable attention in the scientific community due to their unique properties and wide-ranging applications in various fields, including industry and biology. These complexes exhibit diverse biological activities, such as antiviral, cytostatic, antibacterial, anticancer, and antifungal properties, while also displaying exceptional catalytic activity for a wide range of compounds. This review comprehensively explores the history, chemistry, synthesis, and various applications of Schiff-base ligand-based metallic complexes, with a focus on their biological and catalytic applications. The review highlights the current state of research and future directions in the field, serving as a valuable resource for researchers and professionals in the field of inorganic chemistry.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Congjian Ni, Ziyuan Pang, Yuhang Qiao, Pingping Guo, Xiaoli Ma, Zhi Yang
Summary: Organic aluminum compounds derived from halogen-substituted Schiff bases have emerged as a research hotspot in the development of green chemistry. These compounds, characterized by twisted six-membered ring structures, show excellent catalytic performance in the hydroboration of aldehydes and ketones.
INORGANICA CHIMICA ACTA
(2022)
Review
Chemistry, Medicinal
Wardha Zafar, Sajjad H. Sumrra, Zahid H. Chohan
Summary: Clinical reports have emphasized the increasing threat of multidrug resistance due to antibiotic resistance. Research has shown that organic compounds now require metal ions for bio-transformation in order to enhance their potentiality against resistance. Metal based drugs have played an imperative role in developing new strategies with significant biological activity, safety, and efficacy. In recent years, metal based compounds have been of great interest for treating various diseases, filling the gap left by conventional methodologies.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Songul Boy, Fikret Turkan, Murat Beytur, Abdulmelik Aras, Onur Akyildirim, Halide Sedef Karaman, Haydar Yuksek
Summary: Novel N-Mannich bases were synthesized through the Mannich reaction, followed by the synthesis of eight new compounds. These compounds exhibited inhibitory activity against AChE, BChE, and GST enzymes, with the most active inhibitors showing interactions through hydrophobic and hydrogen bonding with the enzymes.
BIOORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Sivasubramanian Pandiarajan, Nallamohamed Hajarabeevi, Rafik Rajjak Shaikh, Sathya Raghunathan, Davoodbasha MubarakAli
Summary: In this study, a novel Schiff base ligand was synthesized and shown to have significant antibacterial activity against Escherichia coli and Staphylococcus aureus.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Review
Chemistry, Inorganic & Nuclear
Chandrabhan Verma, M. A. Quraishi
Summary: Schiff bases (SBs) have the potential to act as corrosion inhibitors for different metal/electrolyte systems, especially when they contain polar substituents. The electron rich centers in SBs play a critical role in forming corrosion mitigating surface films through strong bonding with metallic ions.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Medicinal
Resit Cakmak, Eyup Basaran, Murat Senturk
Summary: In this study, novel Schiff base derivatives containing a pyrazolone ring were synthesized and tested for their inhibitory activities on several enzymes. The compounds showed significant inhibition effects and may serve as potential drug candidates.
ARCHIV DER PHARMAZIE
(2022)
Article
Pharmacology & Pharmacy
Sertan Aytac, Ozlem Gundogdu, Zeynebe Bingol, Ilhami Gulcin
Summary: The design and synthesis of eight Schiff bases and hydrazineylidene derivatives with potential as synthetic antioxidants were studied. These compounds showed significant antioxidant and enzyme inhibition activities.
Article
Chemistry, Organic
Rui-jun Peng, Yuan Chen, Xue-jing Zhang, Ming Yan
Summary: A Rh(iii)-catalyzed ortho C-H migratory insertion of N-nitrosoanilines with naphthoquinone carbenes has been developed, yielding the desired products in good yields under mild reaction conditions. Diverse elaborations of the products were also explored, making this method valuable for the synthesis of biarylamines and their derivatives.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Anja Bec, Maja Cindric, Leentje Persoons, Mihailo Banjanac, Vedrana Radovanovic, Dirk Daelemans, Marijana Hranjec
Summary: In this study, novel N-substituted benzimidazole-derived Schiff bases were designed and synthesized, and their antiviral, antibacterial, and antiproliferative activity were evaluated. The effects of substituents at the N atom of the benzimidazole nuclei and the type of substituents attached at the phenyl ring on the biological activity were investigated. The synthesized Schiff bases were tested for their antiviral activity against different viruses, antibacterial activity against various bacterial strains, and antiproliferative activity on human cancer cell lines, revealing the structure activity relationships. Several compounds showed mild antiviral effects, while some derivatives exhibited moderate antibacterial activity. One particular Schiff base, 4-N,N-diethylamino-2-hydroxy-substituted derivative with a phenyl ring at the N atom on the benzimidazole nuclei, displayed a strong antiproliferative activity against cancer cell lines, especially acute myeloid leukemia (HL-60).
Article
Chemistry, Multidisciplinary
Johan Pierre, Zachary M. Hill, Frank R. Fronczek, Thomas Junk
Summary: A novel synthetic method has been developed for the preparation of 2-N,N-areno[1,3]tellurazoles with high yields. This method is specific to the synthesis of 2-dialkylaminotellurazoles and does not work with sulfur or selenium congeners. X-ray crystallography characterization of selected samples revealed a unique supramolecular structure.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Gaspard Huber, Estelle Leonce, Orsola Baydoun, Nicolas De Rycke, Thierry Brotin, Patrick Berthault
MAGNETIC RESONANCE IN CHEMISTRY
(2018)
Article
Chemistry, Medicinal
N. Daugey, N. De Rycke, T. Brotin, T. Buffeteau
Article
Chemistry, Organic
Pierre Quinodoz, Karen Wright, Bruno Drouillat, Mikhail E. Kletskii, Oleg N. Burov, Anton. V. Lisovin, Francois Couty
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Organic
Nicolas De Rycke, Marion Jean, Nicolas Vanthuyne, Thierry Buffeteau, Thierry Brotin
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Organic
Karen Wright, Bruno Drouillat, Laurence Menguy, Jerome Marrot, Francois Couty
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Keihann Yavari, Wylliam Delaunay, Nicolas De Rycke, Thibault Reynaldo, Paul Aillard, Monika Srebro-Hooper, Victoria Y. Chang, Gilles Muller, Denis Tondelier, Bernard Geffroy, Arnaud Voituriez, Angela Marinetti, Muriel Hissler, Jeanne Crassous
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Medicinal
Orsola Baydoun, Thierry Buffeteau, Nicolas Daugey, Marion Jean, Nicolas Vanthuyne, Laure-Lise Chapellet, Nicolas De Rycke, Thierry Brotin
Article
Chemistry, Organic
Orsola Baydoun, Nicolas De Rycke, Estelle Leonce, Celine Boutin, Patrick Berthault, Erwann Jeanneau, Thierry Brotin
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Physical
Francois Couty, Oleg N. Burov, Mikhail E. Kletskii, Anton V. Lisovin, Karen Wright, Bruno Drouillat, Sergey V. Kurbatov
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
(2020)
Review
Chemistry, Multidisciplinary
Olivier R. P. David
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Multidisciplinary Sciences
Stefi Nouleho Ilemo, Dominique Barth, Olivier David, Franck Quessette, Marc-Antoine Weisser, Dimitri Watel
Review
Chemistry, Multidisciplinary
Yu-Chao Yuan, Mohamed Mellah, Emmanuelle Schulz, Olivier R. P. David
Summary: In this article, the applications of bisimine derivatives of salicylaldehyde with chiral diamines (salens) in asymmetric organometallic catalysis are reviewed and classified according to the organocatalyst. The mechanisms and physical-organic chemistry considerations of these complex catalytic systems are discussed for a better understanding.
Review
Chemistry, Organic
Olivier R. P. David, Franco Doro
Summary: This article reviews major breakthroughs in the field of perfumery, including fragrance ingredients, technological advances in scent delivery, and consumer product innovations. The innovations are presented chronologically, covering a span of 150 years. The article provides a historical overview of the impact of scientific and technological advancements in fragrance chemistry on consumer goods, while honoring pioneering chemists.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Yu-Chao Yuan, Mariam Abd El Sater, Mohamed Mellah, Nada Jaber, Olivier R. P. David, Emmanuelle Schulz
Summary: New procedures for efficient reuse of chiral organic catalysts are in high demand, with the synthesis of a chiral isothiourea functionalized by a pyrene moiety via click chemistry being described in this study. The immobilization of the catalyst on reduced graphene oxide through strong pi-pi interactions led to successful reuse in seven consecutive cycles, demonstrating high yields and good to excellent enantioselectivity values in the targeted product synthesis.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Organic
Bruno Drouillat, Cristina Peggion, Barbara Biondi, Karen Wright, Francois Couty, Marco Crisma, Fernando Formaggio, Claudio Toniolo
ORGANIC & BIOMOLECULAR CHEMISTRY
(2018)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
