期刊
TETRAHEDRON LETTERS
卷 52, 期 3, 页码 434-437出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.11.086
关键词
oligonucleotide synthesis; Phosphorothioate; Sulfurization; Phosphoramidite synthesis
The reactivity of 5-amino-3H-1,2,4-dithiazole-3-thiones substituted at their amino group and 5-amino-3H-1,2-dithiole-3-thiones substituted at their amino group and C4 toward compounds containing P(III) atoms has been studied. N,N-Disubstituted-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)methanimidamides were selected as novel efficient sulfur transfer reagents suitable for DNA and RNA synthesis. (C) 2010 Elsevier Ltd. All rights reserved.
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