Practical synthetic routes to carbon-substituted nucleosides

Robust practical routes to three different carbon-substituted nucleosides are described. Short synthetic procedures for preparing 1'-homonucleosides, 2'-C-methyl-carbanucleosides and 2'-C-methyl-cyclopropyl/cyclopentyl fused bicyclic ribose analogues are described starting from readily available building blocks. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.