期刊
TETRAHEDRON LETTERS
卷 51, 期 6, 页码 966-969出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.12.043
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-
资金
- Department of Science and Technology (DST), Government of India
A novel methodology for the synthesis of N-substituted-3-aryl-2-thioxotetrahydropyrimidin-4(1H)-one derivatives had been developed by the condensation of aryl isothiocyanates with beta-amino esters using lithium perchlorate as a catalyst and triethylamine as a base. This strategy not only overcomes the disadvantages of the reported methods but also provides high yield of the product in short span of time by an easily workable procedure. (C) 2009 Elsevier Ltd. All rights reserved.
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