期刊
TETRAHEDRON LETTERS
卷 51, 期 1, 页码 64-66出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.10.085
关键词
Radiofluorination; Radiopharmaceuticals; Fluoride; F-18; Nucleophilic substitution; Positron emission tomography; SPE
资金
- EU's [FP6 STRP 516984 MI-Lab-On-Chip]
- FRS-F.N.R.S. Belgium
The use of a polymeric solid support loaded with a long alkyl chain quaternary ammonium allows the rapid and efficient recovery of cyclotron produced [F-18]F- from [O-18]water to a low water content organic solution compatible with fast nucleophilic labelling of most precursors for PET radiopharmaceuticals in high yield. (C) 2009 Elsevier Ltd. All rights reserved.
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