Intramolecular Pauson-Khand reaction of optically active aza-Baylis-Hillman adducts

The intramolecular Pauson-Khand reaction of aza-Baylis-Hillman adducts, which were prepared through the thio-Michael/imino-aldol domino reaction of optically active sulfinimines, was examined and gave optically active cis- and trans-pyrrolidine-fused cyclopentenones in a stereoselective manner. (C) 2010 Elsevier Ltd. All rights reserved.