期刊
TETRAHEDRON LETTERS
卷 50, 期 40, 页码 5625-5627出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.07.115
关键词
Silica gel; Multi-component reaction; Isocyanide; 2-Hydroxy-5-nitro-benzaldehyde; 2-Hydroxy-5-bromo-benzaldehyde; Secondary amine; Benzo[b]furan; Iminium ion
资金
- Iran National Science Foundation: INSF
Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between an electron-poor 2-hydroxybenzaldehyde derivative and a secondary amine in the presence of silica gel proceeds smoothly at room temperature to afford benzo[b]furan derivatives in high yields. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.
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