Article
Chemistry, Analytical
Ting Liu, Lixing Fu, Chenhui Yin, Meng Wu, Ligang Chen, Na Niu
Summary: A smartphone platform utilizing ratiometric fluorescence signals was developed for fast, sensitive, and on-site visual detection of silver ions. By constructing a ratiometric fluorescent probe with FITC and CdTe QDs, the color changes of the system were captured on a portable smartphone platform, enabling the visual analysis of Ag+ in environmental water samples at low detection limits.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Yuan Zhang, Chunmeng Ma, Chen Ma, Yueci Xiang, Shuai Mu, Zhixiang Zheng, Xiaoyan Liu, Haixia Zhang
Summary: The study utilized manganese dioxide nanosheets as carriers to deliver DNAzyme probes into cells, where intracellular glutathione reduced the nanosheets to release probes for miRNA detection. The newly proposed method offers a rapid and sensitive approach for imaging miRNA-155 in cancer cells, contributing to cancer diagnosis and biological research.
Article
Chemistry, Physical
Liu Yang, Yu-Long Liu, Cheng-Guo Liu, Ying Fu, Fei Ye
Summary: HNA is a dual-platform colorimetric and ratiometric chemosensor designed to detect fluoride anion in DMSO solution. It shows excellent selectivity and sensitivity, with color changes from yellow to purple when F- is present. The detection limit is as low as 0.61 mu M, and it has a binding model with F- in a 3:2 stoichiometry ratio. HNA has the potential to be a superior chemosensor for monitoring F- selectively and sensitively.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Sha Li, Fangjun Huo, Kaiqing Ma, Yongbin Zhang, Caixia Yin
Summary: A highly sensitive cyanide probe was developed, which can rapidly detect cyanide ions within 40 seconds and can be monitored by the naked eye, with a low detection limit. Furthermore, the probe can be used in biological determination of cyanide poisoning.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Zhiyong Zhuang, Fanling Meng, Liang Luo
Summary: Poly-deca-4,6-diynedioic acid (PDDA) is a conjugated polymer capable of selectively detecting zinc ions (Zn2+) and efficiently removing Zn2+ from water samples.
ORGANIC ELECTRONICS
(2021)
Article
Engineering, Environmental
Long Ma, Jiajing Wang, Yaru Li, Dan Liao, Wenlu Zhang, Xiao Han, Shuli Man
Summary: We developed a versatile biosensing platform, SCENT-Cas (Silver nanoCluster Empowered Nucleic acids Test using CRISPR/Cas12a), for ultrasensitive detection of pathogenic bacteria. This platform used the isothermal amplification of the invA gene of Salmonella typhimurium to trigger trans-cleavage of CRISPR/Cas12a. The trans-cleavage was then utilized to degrade single-stranded DNA and create a ratiometric fluorescence biosensing platform. This method enabled the detection of 1 CFU/mL S. typhi with a dynamic range from 1 to 108 CFU/mL, and showed promise for real food sample testing.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Spectroscopy
Huimin Shangguan, Qianwei Liu, Yuanjuan Wang, Zixuan Teng, Rumeng Tian, Tong Wu, Lei Yang, Ling Jiang, Xingjiang Liu, Liuhe Wei
Summary: In this study, a chromenoquinoline-based ratiometric fluorescent probe was developed for the detection and quantification of hypochlorous acid (HClO). The probe exhibited a large Stokes shift, high synthetic yield, simple synthesis method, short response time, low detection limit, and low toxicity. The probe was successfully validated in live cells and zebrafish.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Yayu Yang, Xiangmin Lei, Borui Liu, Haochi Liu, Jianan Chen, Guozhen Fang, Jifeng Liu, Shuo Wang
Summary: Metalloenzyme mimics were designed and combined with quantum dots (QDs) to construct a visible ratiometric fluorescent probe for detecting organophosphorus pesticides (OPs). The metalloenzyme mimics recognized and hydrolyzed OPs to produce p-Nitrophenol (PNP), while the QDs served as the indicator. The biosensor demonstrated high sensitivity and fast detection speed, making it suitable for real sample analysis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Dandan Zhao, Yijun Huang, Huixiang Ouyang, Bingfang Shi, Suping Li, Shengyu Chen, Shulin Zhao
Summary: A novel fluorescent probe incorporating Cu-doped carbon dots was developed for naked-eye discrimination of phenylenediamine isomers and highly sensitive ratiometric fluorescence detection of H2O2. The sensor showed outstanding peroxidase-like activity and stability, and was able to detect H2O2 with a detection limit of 5.0 nM, with potential applications in biologically related studies.
Article
Engineering, Biomedical
Samuel Babity, Frederic Couture, Estefania V. R. Campos, Sarah Hedtrich, Raphael Hagen, Daniel Fehr, Mathias Bonmarin, Davide Brambilla
Summary: This study proposes a minimally invasive alternative strategy of delivering fluorescent ratiometric sensors to the skin using dissolving polymeric microneedles for real-time monitoring of physiological and pathological parameters. The sensors are capable of detecting reactive oxygen species, and are coupled with a custom-built, multiwavelength portable fluorescence detection system.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Environmental
Pramod Kumar Mehta, Lok Nath Neupane, See-Hyoung Park, Keun-Hyeung Lee
Summary: The study synthesized an aggregation-induced emission fluorophore and developed a corresponding fluorescent peptidyl probe for selective detection of silver ions and silver nanoparticles in water. This fluorescent detection method allows for rapid and accurate quantification of silver nanoparticles in water.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Gopal Balamurugan, Jae Woong Jang, Se Jeong Park, Sekar Vikneshvaran, Jong S. Park
Summary: This article introduces a sulfur-functional group-free silver-selective probe that exhibits distinctive colorimetric and photothermal responses through the oxidation reaction of silver ions to form quinone diimminium salts. This probe demonstrates high selectivity and low detection limits, enabling the detection of silver ions through colorimetric and photothermal methods.
Article
Biochemical Research Methods
Xiang Li, Zhong Lin, Yong Tian, Chonghua Zhang, Peisheng Zhang, Rongjin Zeng, Lei Qiao, Jian Chen
Summary: In this study, a novel negative photochromic spiropyran derivative, MAHD-SP, was designed with stable ring-opened state and notable orange fluorescence. The fluorescence of MAHD-SP was quenched by the Michael addition reaction of SO2 derivative. A ratiometric fluorescent polymeric nanoprobe (RFPN) was constructed using MAHD-SP, a fluorescent conjugated polymer PFO, and a polymeric surfactant PEO113-b-PS49. The RFPN exhibited high sensitivity and selectivity for the ratiometric detection of SO2 derivatives in aqueous solutions, and could visualize SO2 derivative generation in living cells.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Kirara Ishida, Yushi Nakamura, Tetsuo Ohta, Yohei Oe
Summary: A molecular probe containing l-phenylalanine p-nitroanilide and l-lysin 4-methylcoumaryl-7-amide connected through a succinic-acid spacer was prepared for detection of enzymes like trypsin and papain. Different time courses of p-nitroanilide and AMC were observed between reactions with alpha-chymotrypsin and nattokinase, showing distinct fluorescence and UV absorbance characteristics.
Article
Spectroscopy
Mingxin Li, Yu Gao, Yan Zhang, Shuai Gong, Xuechun Tian, Yiqin Yang, Xu Xu, Zhonglong Wang, Shifa Wang
Summary: A highly sensitive fluorescent probe NQBS was designed and synthesized to detect malononitrile, which exhibited selective recognition towards malononitrile among 26 competitive compounds. The sensing mechanism of NQBS towards malononitrile was verified through mass spectrometer, nuclear magnetic resonance, and density functional theory analysis, showing a Knoevenagel condensation process and intramolecular cyclization reaction. The application of NQBS in on-site real-time recognition of malononitrile was successful with the assistance of smartphone and color recognition software.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Applied
Anoop Singh, Narinder Singh, Navneet Kaur, Doo Ok Jang
Summary: A novel biomass-derived heterogeneous catalyst has been developed for the selective reduction of nitro compounds, which is effective in various environmentally friendly applications.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Amanpreet Singh, Gagandeep Singh, Shilpa Sharma, Navneet Kaur, Narinder Singh
Summary: In this study, a metal-free and green catalyst based on sulfonic acid functionalized carbon quantum dots (CQDs) derived from biomass was designed and developed for one pot multicomponent reactions. The catalyst exhibited excellent reusability and catalytic activity for the synthesis of biologically important heterocycles in pure aqueous medium.
Article
Chemistry, Applied
Anoop Singh, Narinder Singh, Navneet Kaur
Summary: In this study, fluorescent conjugated and nonconjugated polythioamide were synthesized using a one-pot method with dialdehyde, diamines, and elemental sulfur, in the presence of IL1-IL2@Fe(3)O(4)NPs as a catalyst via the Willgerodt-Kindler reaction. A magnetized iron nanoparticles heterogeneous catalyst coated with an ionic liquid was synthesized. The catalyst was characterized by BET, XPS, PXRD, TEM, and FTIR spectroscopy. The multicomponent reaction proceeded smoothly at ambient temperature with excellent yield in the presence of the catalyst. The magnetic catalyst could be easily recovered, indicating the potential of this method for efficient polymerization of structurally diversified polythioamides.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Analytical
Geetika Bhardwaj, Randeep Kaur, Navneet Kaur, Narinder Singh
Summary: A new receptor R1 was synthesized and prepared as nanoparticles to detect azidothymidine. The nanoparticle probe showed better sensing performance for azidothymidine in various techniques such as cyclic voltammetry.
Article
Food Science & Technology
Nouratan Singh, Poonam Rani, Neeraj Tandan, Dinesh Kumar Arya, Ansuman Mahato
Summary: An Ultra-High-Performance Liquid Chromatography (UHPLC) method was developed and validated for the analysis of 16 PAH compounds in soil samples from Manesar, India. The study found that PAH concentrations were highest in the winter season in industrial areas, while the lowest levels were observed during the monsoon season. The PAH levels in Manesar were relatively lower compared to Brazil, UK, Germany, and Korea.
JOURNAL OF MICROBIOLOGY BIOTECHNOLOGY AND FOOD SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Randeep Kaur, Geetika Bhardwaj, Narinder Singh, Navneet Kaur
Summary: A simplistic, versatile, and general approach to constructing functionalized electrochemical materials is described in this study. This approach involves modifying multiwalled carbon nanotubes (MWCNT) with dipodal naphthyl-based dipodal urea (KR-1) through non-covalent functionalization, complexing the modified MWCNT with Hg2+ to enhance electron transfer and detection response, and applying the functionalized electrochemical material (Hg/KR-1@MWCNT) for real-time electrochemical monitoring of harmful antiviral drug (IUdR) levels in human serum.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
Harpreet Kaur, Divya, Navneet Kaur, Narinder Singh
Summary: Exposure to CO2 has harmful effects on human health and the environment. In this study, we developed an electrochemical method using calix [4]Arene-based nanohybrids for the detection of dissolved CO2 and its conversion into formic acid. This sustainable method has high efficiency and practical utility.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Chemistry, Multidisciplinary
Anoop Singh, Narinder Singh, Navneet Kaur, Doo Ok Jang
Summary: A chitosan-poly(vinyl alcohol)-ionic liquid-grafted hydrogel was prepared and characterized for water purification. The swelling properties of the hydrogel were optimized, and it showed a maximum swelling of 330%. The hydrogel exhibited high removal rates for dye, nitrite, and Pb2+, and could effectively recover oil from an oil-water mixture due to electrostatic interactions.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Amanpreet Singh, Gagandeep Singh, Navneet Kaur, Narinder Singh
Summary: A DNA/Carbon Quantum Dot (CQD) based hybrid nanoarchitecture system was developed for the selective detection of Ochratoxin A (OTA). The system showed modulation in the emission spectrum after interaction with OTA, with a binding constant of 3.5 x 10(5) M-1, a limit of detection of 14 nM, limit of quantification of 47 nM, and working range of 1-10 mu M. The binding mode of the CQD@DNA hybrid nanoarchitecture assembly with OTA was confirmed using fluorescence, UV-visible absorption spectroscopy, and FTIR techniques. The system was also demonstrated to effectively quantify OTA in real food monitoring analysis, making it a potential candidate for convenient food safety and quality monitoring for human health.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Physical
Geetika Bhardwaj, Randeep Kaur, Sanjeev Saini, Navneet Kaur, Narinder Singh
Summary: This study presents a method for detecting insulin using a 4H-chromene derivative surface decorated with AgNPs. The method exhibits a low detection limit, high sensitivity, and excellent reproducibility, and can accurately detect insulin in both liquid and solid state. This cost-effective and environment friendly method has significant implications in the field of diabetes management.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Multidisciplinary
Amanpreet Singh, Monika Chaudhary, Meenakshi Verma, Navneet Kaur, Narinder Singh
Summary: Anion-induced self-assembly is a growing research field that provides a better understanding of natural self-assemblies such as DNA, proteins, peptides, etc. In this study, nanohybrids of glutathione tripeptide and naphthalimide based compounds were fabricated and their self-assembly behavior was explored. The nanohybrids showed enhanced fluorescence intensity with bisulphate anions, indicating potential applications in bisulphate recognition. The morphology of the nanohybrids was studied using HRTEM and STEM.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Geetika Bhardwaj, Randeep Kaur, Sanjeev Saini, Navneet Kaur, Narinder Singh
Summary: A sensor based on Ni@G1 core-shell nanoparticles has been developed, which exhibits high selectivity and sensitivity for BrdU detection. The sensor can detect BrdU with a detection limit of 9 nM in an aqueous medium, and shows no significant interference from pH, salt, and temperature.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Mathematical & Computational Biology
Poonam Rani, Nouratan Singh, Monika Bhaskar, Neeraj Tandan
Summary: This study surveyed the microbial community and their antibiotic profiling in the domestic environment of rural and urban areas in Meerut city, India. The results revealed a higher bacterial load compared to fungal load, with kitchens being more contaminated than living rooms. The dominant bacteria were Pseudomonas sps, Citrobacter sps, Bacillus Subtilis, Brevundimonas diminuta, Bacillus megaterium, and Klebsiella pneumoniae. Antibiotic resistance was mainly derived from plasmids.
Article
Chemistry, Multidisciplinary
Manish Kumar, Navneet Kaur, Narinder Singh
Summary: This study reports the development of CuNi alloy nanoparticle-decorated MWCNTs stabilized by an ionic liquid for the sensitive detection and detoxification of imidacloprid. The material exhibited excellent electrocatalytic activity and selectivity towards imidacloprid, as well as high recovery rates in spiked corn and rice samples. Moreover, it achieved almost complete degradation of imidacloprid in aqueous systems with good reusability.
ENVIRONMENTAL SCIENCE-NANO
(2022)
Article
Chemistry, Multidisciplinary
Anoop Singh, Sanjeev Saini, Narinder Singh, Navneet Kaur, Doo Ok Jang
Summary: Cellulose was extracted from rice straw and a highly active solid-supported catalytic model was developed in this study. By conjugating with poly(ethylene-co-vinyl acetate) (PEVA) and inserting silver nanoparticles, a composite catalyst was successfully fabricated. The hybrid catalyst exhibited excellent reaction yields in the Willgerodt-Kindler reaction and showed high stability and recyclability.
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
