Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae

A new metamorphis-enhancing maciodiohide, luminaolide (1), was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldn. Its structure was determined by spectroscopic analysis A fraction (130 mu g/mL) eluted with 80% aqueous MeOH by ODS gel column chromatography of the same CCA extract induced larval metamorphosis (25.9 +/- 74%) against Leptastrea purpurea, and its metamorphosis-inducing activity was further enhanced to 92.6 +/- 29% with the addition of 1 (25.6 ng/mL) (C) 2009 Elsevier Ltd. All rights reserved