N-chlorosuccinimide as a versatile reagent for the sulfenylation of ketones:: a facile synthesis of α-ketothioethers

The sulfenylation of ketones having alpha-hydrogens has been achieved using N-chlorosuccinimide (NCS) under mild reaction conditions to produce alpha-ketothioethers in excellent yields with high selectivity. The use of NCS makes this method quite simple, convenient and practical. (C) 2008 Published by Elsevier Ltd.