Review
Chemistry, Inorganic & Nuclear
Ling Zhang, Mark G. Humphrey
Summary: Materials exhibiting multi-photon absorption (MPA), such as metal alkynyl complexes, have significant potential applications in microfabrication, bio-imaging and sensing, and photodynamic therapy. The collinear structure of metal and alkynyl ligand in these complexes promotes strong electron delocalization and intra-molecular charge transfer, leading to outstanding MPA behavior.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Daniel Himmelbauer, Radu Talmazan, Stefan Weber, Jan Pecak, Antonio Thun-Hohenstein, Maxine-Sophie Geissler, Lukas Pachmann, Marc Pignitter, Maren Podewitz, Karl Kirchner
Summary: The synthesis of imines is a foundational aspect of organic chemistry. Alcohols can be used as renewable substitutes for carbonyl-functionality, allowing for the in situ generation of carbonyl moieties from alcohols using transition-metal catalysis under inert atmosphere or bases under aerobic conditions. In this study, we report the synthesis of imines from benzyl alcohols and anilines using (KOBu)-Bu-t as a catalyst under aerobic conditions at room temperature, without the need for a transition-metal catalyst. We also present a detailed investigation of the underlying radical mechanism, revealing a complex reaction network that supports the experimental findings.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Organic
Zhenfa Li, Lan Zhao, Liuyi Liang, Lixin Zhao, Fangyi Li, Chunhua Wang, Zheng Li
Summary: The additive-free copper(I)-bromide-mediated radical cyclization reactions of alpha,alpha-dibromo beta-iminoesters successfully enabled the synthesis of a series of 5- or 6-brominated 2-aryl-1H-indole-3-carboxylates in moderate to good yields. Mechanistic study revealed the bromine atom originated from the substrates and the bromination might be related to a 3-bromo-3H indole intermediate.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Karthik Gadde, Bert U. W. Maes, Kourosch Abbaspour Tehrani
Summary: An efficient metal-free strategy has been developed for the synthesis of alpha-substituted homoallylamine derivatives via a 2-aza-Cope rearrangement promoted by HFIP. This method provides rapid access to the desired products with excellent functional group tolerance and high yields, without the need for chromatographic purification. The synthetic utility of this method is further demonstrated through the transformation of benzophenone ketimines into various compounds.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Engineering, Electrical & Electronic
Liyuan Shen, Jingjing Li, Lin Zuo, Lei Zhu, Heng Tao Shen
Summary: This article discusses a more difficult yet more practical source-free transfer setting, where there are only the models pretrained in source domain and limited target data can be available. To address the challenges of the absence of source data and distribution discrepancy in cross-domain SOC estimation, a novel source-free temperature transfer network (SFTTN) is proposed, which can mitigate domain shift adaptively. Experiment results indicate that SFTTN can achieve robust and accurate SOC estimation at different ambient temperatures under source-free scenario.
IEEE TRANSACTIONS ON POWER ELECTRONICS
(2023)
Article
Chemistry, Applied
Jian-Lin Xu, Chao Yang, Dong-Ting Dai, Wei-Shu Hou, Yun-He Xu
Summary: beta-Alkynyl substituted gamma,gamma-difluoroallyl-boronates were prepared through defluorination under basic condition. Allylation reaction of aldehydes with gem-difluoroallylboronates in water under metal-free condition was developed, with water as the sole solvent significantly improving the efficiency of the reaction and yielding the desired products in 48-92% yields. The corresponding difluorinated alcohols were smoothly transformed into the 3,3-difluoro-4-methylene-3,4-dihydro-2H-pyran derivatives in the presence of gold catalyst.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Materials Science, Multidisciplinary
Hossein Karampour, Mohammad Ahmadi Parsa, Ali Heidary Moghadam, Bahram Pourhasan, Rouholah Ashiri
Summary: The development of a new method for the preparation of high-purity nanocrystalline hydroxyapatite at room temperature, with subsequent optimization for cost-effectiveness, was a significant achievement in this study.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Chemistry, Applied
Yi-En Liang, Balaji D. Barve, Yao-Haur Kuo, Hsu-Wei Fang, Ting-Shen Kuo, Wen-Tai Li
Summary: A base-mediated, green, microwave-assisted efficient method for the synthesis of a diverse benzoxanthone library from readily accessible gamma-alkynyl 1,3-diketones was reported in this study. The synthesis involves tandem reactions including intramolecular cyclization, propargyl-allenyl isomerization, and electrocyclization in one pot, resulting in the formation of new C-C and C-O bonds.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Plant Sciences
Asanga Deshappriya Nagalla, Noriko Nishide, Ken-ichiro Hibara, Takeshi Izawa
Summary: This study found that photoperiodic flowering in rice is enhanced under low-temperature conditions, while rapid reduction of Ghd7 messenger RNA under high-temperature conditions can lead to an increase in the mRNA of a rice florigen gene, RFT1. Multiple temperature-sensing mechanisms can affect photoperiodic flowering in rice.
PLANT AND CELL PHYSIOLOGY
(2021)
Article
Chemistry, Inorganic & Nuclear
Sheeba Khan, Datta Markad, Sanjay K. Mandal
Summary: In this study, two coordination polymers were synthesized as catalysts and used to efficiently produce α-aminonitriles through a solvent-free reaction. The importance of open metal sites in catalysis was demonstrated, and a wide substrate scope, including a natural product synthesis, was achieved.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Zhe Zhou, Zachary S. Sales, Daniel J. Pippel, Michael Qian, Connor L. Martin
Summary: We present a photocatalyst-free, diastereoselective decarboxylative alkylation method for (hetero)aryl sulfinimines using redox-active esters under blue light. This mild and efficient protocol demonstrates its utility as a versatile synthetic tool, especially for medicinal chemists.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Duihai Tang, Tao Wang, Wenting Zhang, Zhen Zhao, Ling Zhang, Zhen-An Qiao
Summary: A liquid metal interfacial engineering strategy was developed for the synthesis of porous carbon with abundant functional groups using CCl4 as the carbon precursor and NaK as the reducing agent. This method allows for the direct generation of porous carbon at ambient temperature through the engineering of a highly active liquid metal alloy microemulsion. The synthesized porous carbon can be tandem-grafted with specific compounds to achieve a CO2 cycloaddition catalyst, which exhibits excellent catalytic activity and stability.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Davide Ripepi, Riccardo Zaffaroni, Herman Schreuders, Bart Boshuizen, Fokko M. Mulder
Summary: The study demonstrates a new electrochemical method for producing ammonia at room temperature, reducing carbon emissions and saving energy. By spatially separating the electrolyte and hydrogen reduction side from the dinitrogen activation and hydrogenation sites, the strategy successfully achieved the electrochemical reaction of hydrogen and nitrogen gas.
ACS ENERGY LETTERS
(2021)
Article
Environmental Sciences
A. Plevri, D. Mamais, C. Noutsopoulos
Summary: This study investigates the efficiency of Anaerobic Membrane Bioreactor (AnMBR) under different temperatures and operating conditions, finding that as the hydraulic retention time decreases, effluent quality decreases and membrane fouling occurs more rapidly.
Article
Chemistry, Organic
Junli Zhu, Cancan Dai, Mengyue Ma, Yanni Yue, Xinyuan Fan
Summary: A catalytic system utilizing visible light iridium photoredox catalysis has been developed for synthesizing alpha-amino amides through the umpolung reactivity of ketimines. Cross-couplings between various ketimine and isocyanate substrates have been evaluated, leading to good yields of the desired products. Additionally, a metal-free catalytic system and the successful synthesis of a benzodiazepine-2-one analogue indicate the significant application potential of the developed synthetic method.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Multidisciplinary Sciences
Haibin Zhou, Jianfeng Lu, Liu Liu, Denzil Bernard, Chao-Yie Yang, Ester Fernandez-Salas, Krishnapriya Chinnaswamy, Stephanie Layton, Jeanne Stuckey, Qing Yu, Weihua Zhou, Zhenqiang Pan, Yi Sun, Shaomeng Wang
NATURE COMMUNICATIONS
(2017)
Article
Chemistry, Medicinal
Haibin Zhou, Weihua Zhou, Bing Zhou, Liu Liu, Ting-Rong Chern, Krishnapriya Chinnaswamy, Jianfeng Lu, Denzil Bernard, Chao-Yie Yang, Shasha Li, Mi Wang, Jeanne Stuckey, Yi Sun, Shaomeng Wang
JOURNAL OF MEDICINAL CHEMISTRY
(2018)
Article
Agricultural Engineering
Hai-Bin Zhou, Chuang Ma, Ding Gao, Tong-Bin Chen, Guo-Di Zheng, Jun Chen, Tian-Hao Pan
BIORESOURCE TECHNOLOGY
(2014)
Article
Agricultural Engineering
Hai-Bin Zhou, Tong-Bin Chen, Ding Gao, Guo-Di Zheng, Jun Chen, Tian-Hao Pan, Hong-Tao Liu, Run-Yao Gu
BIORESOURCE TECHNOLOGY
(2014)
Article
Chemistry, Medicinal
Angelo Aguilar, Haibin Zhou, Jianfang Chen, Liu Liu, Longchuan Bai, Donna McEachern, Chao-Yie Yang, Jennifer Meagher, Jeanne Stuckey, Shaomeng Wang
JOURNAL OF MEDICINAL CHEMISTRY
(2013)
Article
Chemistry, Medicinal
Haibin Zhou, Liu Liu, Jing Huang, Denzil Bernard, Hacer Karatas, Alexandro Navarro, Ming Lei, Shaomeng Wang
JOURNAL OF MEDICINAL CHEMISTRY
(2013)
Article
Multidisciplinary Sciences
Longchuan Bai, Jianfang Chen, Donna McEachern, Liu Liu, Haibin Zhou, Angelo Aguilar, Shaomeng Wang
Article
Oncology
Longchuan Bai, Haibin Zhou, Renqi Xu, Yujun Zhao, Krishnapriya Chinnaswamy, Donna McEachern, Jianyong Chen, Chao-Yie Yang, Zhaomin Liu, Mi Wang, Liu Liu, Hui Jiang, Bo Wen, Praveen Kumar, Jennifer L. Meagher, Duxin Sun, Jeanne A. Stuckey, Shaomeng Wang
Article
Chemistry, Medicinal
Haibin Zhou, Longchuan Bai, Renqi Xu, Yujun Zhao, Jianyong Chen, Donna McEachern, Krishnapriya Chinnaswamy, Bo Wen, Lipeng Dai, Praveen Kumar, Chao-Yie Yang, Zhaomin Liu, Mi Wang, Liu Liu, Jennifer L. Meagher, Han Yi, Duxin Sun, Jeanne A. Stuckey, Shaomeng Wang
JOURNAL OF MEDICINAL CHEMISTRY
(2019)
Article
Chemistry, Medicinal
Ting-Rong Chern, Liu Liu, Elyse Petrunak, Jeanne A. Stuckey, Mi Wang, Denzil Bernard, Haibin Zhou, Shirley Lee, Yali Dou, Shaomeng Wang
ACS MEDICINAL CHEMISTRY LETTERS
(2020)
Article
Chemistry, Medicinal
Haibin Zhou, Longchuan Bai, Renqi Xu, Donna McEachern, Krishnapriya Chinnaswamy, Ruiting Li, Bo Wen, Mi Wang, Chao-Yie Yang, Jennifer L. Meagher, Duxin Sun, Jeanne A. Stuckey, Shaomeng Wang
Summary: SD-91 is a potent, highly selective, and efficacious STAT3 degrader that effectively induces degradation of STAT3 protein with high selectivity, demonstrating complete and long-lasting tumor regression in preclinical models. It has the potential for extensive evaluations in the treatment of human cancers and diseases where STAT3 plays a critical role.
ACS MEDICINAL CHEMISTRY LETTERS
(2021)
Article
Multidisciplinary Sciences
Haibin Zhou, Jianfeng Lu, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Liu Liu, Donna McEachern, Chao-Yie Yang, Denzil Bernard, Hong Shen, Liangyou Rui, Yi Sun, Shaomeng Wang
Summary: The study identifies two potent and selective covalent DCN1 inhibitors that selectively inhibit cullin-3 neddylation in cells, leading to increased NRF2 protein levels and protection of mice from liver damage.
NATURE COMMUNICATIONS
(2021)
Meeting Abstract
Chemistry, Multidisciplinary
Haibin Zhou, Jianfeng Lu, Liu Liu, Denzil Bernard, Jeanne Stuckey, Yi Sun, Shaomeng Wang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)
Meeting Abstract
Chemistry, Multidisciplinary
Jianfang Chen, Haibin Zhou, Angelo Aguilar, Liu Liu, Longchuan Bai, Chao-Yie Yang, Donna McEachern, Jennifer Meagher, Jeanne Stuckey, Shaomeng Wang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
Meeting Abstract
Chemistry, Multidisciplinary
Angelo Aguilar, Haibin Zhou, Jianfang Chen, Liu Liu, Longchuan Bai, Chao-Yie Yang, Donna McEachern, Jennifer Meagher, Jeanne Stuckey, Shaomeng Wang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
