4.4 Article

Iron-catalyzed cross-coupling of aryltrimethylammonium triflates and alkyl Grignard reagents

期刊

TETRAHEDRON
卷 69, 期 46, 页码 9580-9585

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.09.039

关键词

Aryltrimethylammonium salt; C-N activation; Alkylation; Grignard reagents; Iron catalyst; Cross-coupling

资金

  1. National Basic Research Program of China [2009CB825300]
  2. National Natural Science Foundation of China [21172208]

向作者/读者索取更多资源

Fe(acac)(3) effectively catalyzes reaction of aryltrimethylammonium triflates with beta-hydrogen-containing primary or secondary alkyl Grignard reagents in a mixed solvent of THF and NMP at room temperature. A series of functional groups are tolerated under the reaction conditions. (c) 2013 Elsevier Ltd. All rights reserved.

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