Article
Chemistry, Organic
Namdeo M. Chavhan, Sagar D. Bhakare, Rohit C. Muthe, Sayaji Y. Hande, Amol S. Gandule, Dhananjay N. Gaikwad, Dayanand M. Suryawanshi
Summary: This study presents an efficient, green, and direct approach for the synthesis of amido alkyl naphthols, utilizing a one-pot multicomponent solvent-free reaction. The reaction is catalyzed by easily available, non-toxic, and cost-effective Lewis acid catalyst magnesium sulphate (MgSO4 center dot 7H(2)O). The important characteristics of this approach include eco-friendly and mild reaction conditions, excellent yields of the products, shorter reaction time, and economically cheaper and environmentally friendly catalyst.
LETTERS IN ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Applied
Chun-Wei Kuo, Naidu Sambasiva Rao, Prakash Bhimrao Patil, Ting-Ta Chiang, Veerababurao Kavala, Ching-Fa Yao
Summary: A new method has been developed for the metal and solvent-free one-pot cascade synthesis of perinaphthenones from 1-naphthols and ynones mediated by (BF3Et2O)-Et-. This strategy allows for the formation of new periannulation at C-4-C-5 positions of alpha-naphthol, resulting in highly substituted perinaphthenones with good to moderate yields. The synthesized perinaphthenones products exhibit interesting photo physical properties.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Organic
Chikkappaiahnayaka Santhosh, Krishna Ravi Singh, Kalleshappa Sheela, Toreshettahally R. Swaroop, Maralinganadoddi P. Sadashiva
Summary: An acid-catalyzed regioselective cyclization reaction of 2,5-disubstituted-1,3,4-thiadiazoles and 1,3,4-oxadiazoles has been developed. The precursors alkyl 2-(methylthio)-2-thioxoacetates/alkyl 2-amino-2-thioxoacetates react efficiently with acyl hydrazides, leading to a series of dehydrative and desulfurative products. Among the mentioned procedures, the alkyl 2-amino-2-thioxoacetate pathway shows excellent yield. The reported methods are operationally simplistic and highly efficient with metal-free conditions, demonstrating significant functional group compatibility. Regioselective cyclized products were confirmed by single-crystal X-ray diffraction studies.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Tandra Kundu, Bijeta Mitra, Pranab Ghosh
Summary: This article describes a simple and efficient synthesis method based on humic acid, which can catalyze the synthesis of 1-amidoalkyl-2-naphthols and 1-thioamidoalkyl-2-naphthols in water. The method has advantages such as moderate to excellent yields, easy operation, mild reaction conditions, the use of water as a green solvent, and a reusable catalyst.
SYNTHETIC COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Gang Wang, Yage Geng, Zejing Zhao, Qiuping Zhang, Xiang Li, Zhiqiang Wu, Shuxian Bi, Haijuan Zhan, Wanyi Liu
Summary: This article reports a new method for the preparation of xanthene and pyrimidinone compounds by a one-pot method using polymeric aluminum chloride (PAC) and silica gel under mechanical grinding conditions. The reconstitution of PAC and silica gel during the grinding process leads to the formation of a new composite catalyst (PAC-silica gel), which exhibits good stability and wide applicability. The formation of the Al-O-Si active center through in situ grinding recombination is revealed to be the key to the effective catalytic performance of the PAC-silica gel composites. Mechanical ball milling serves as both a self-assembly inducer and a driving force for the catalytic reaction. This one-pot catalytic method eliminates the need for complex preparation processes for catalytic materials and shows the successful application of mechanochemistry in materials and organic synthesis.
Article
Engineering, Chemical
Jinglu Han, Guolong Wu, Yanling Li, Songsong Li, Wuping Liao
Summary: In order to overcome the drawbacks of the commonly used naphthenic acid (NA) system for yttrium (Y) separation, a novel extractant, 2-(bis((2-ethylhexyl)oxy)phosphoryl)-2-hydroxy-acetic acid (HPOAc, HL), was designed and synthesized by combining the functional groups of commercial organophosphorus extractants, carboxylic acids, and alcohol phase modifiers. HPOAc showed higher extraction ability for REEs(III) and better performance in the separation of Ln(III) and Y(III) compared to NA and CA-12. A cascade extraction process using HPOAc as the extractant was developed, achieving a Y product with a purity of 99.31 wt% through 20 stages of extraction and 4 stages of scrubbing.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Ahmad Reza Moosavi-Zare, Raha Najafi
Summary: Trityl chloride was efficiently used as a neutral catalyst for the multicomponent cyclization reaction of an aldehyde with dimedone and 6-amino-1,3-dimethyluracil for the preparation of pyrimido[4,5-b] quinolines in chloroform under reflux condition.
SCIENTIFIC REPORTS
(2023)
Article
Biochemical Research Methods
Navid Irannejad-Gheshlaghchaei, Seyed Sajad Sajadikhah
Summary: The study utilized nano-[DSPECDA][HSO4] as a catalyst for the synthesis of 1-thioamidoalkyl-2-naphthols and tetrahydropyridine derivatives under mild and solvent-free conditions. The products were characterized by IR, NMR, and Mass spectroscopy, showing better reaction results compared to literature, in line with green chemistry protocols.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
(2021)
Article
Chemistry, Multidisciplinary
Lianmin Ji, Licheng Zhang, Dong Shi, Xiaowu Peng, Jinfeng Li, Yuze Zhang, Taoshan Xu, Lijuan Li
Summary: A novel amide system containing N,N-bis (2-ethylhexyl)-2-methoxyacetamide (NBEHMOA), FeCl3 6H(2)O, and sulfonated kerosene was proposed for continuous extraction of lithium chloride from brines with high Mg/Li ratio. NBEHMOA showed higher and more stable Li+ and H+ extraction efficiency compared to conventional TBP and N523. The counter-current extraction process achieved high Li+ extraction efficiency and Li+ concentration in the stripping solution. FT-IR spectroscopy revealed the coordination mechanism between NBEHMOA and metal ions.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Chemistry, Organic
Yusra Abdelhamid, Kevin Kasten, Joanne Dunne, Will C. Hartley, Claire M. Young, David B. Cordes, Alexandra M. Z. Slawin, Sean Ng, Andrew D. Smith
Summary: This study reports a method for enantioselective [2 + 2] cycloaddition of C(1) ammonium enolates generated catalytically using the isothiourea HyperBTM with N-alkyl isatins, which leads to the formation of spirocyclic beta-lactones. In situ ring opening with an amine nucleophile generates isolable highly enantioenriched products with a diastereomeric ratio of up to 92:8 and an enantiomeric ratio of > 99:1.
Article
Chemistry, Multidisciplinary
Wanderson C. de Souza, Bianca T. Matsuo, Priscilla M. Matos, Jose Tiago M. Correia, Marilia S. Santos, Burkhard Koenig, Marcio W. Paixao
Summary: N-Alkyl-N-(2-(1-arylvinyl)aryl)cinnamamides can be converted into natural product inspired scaffolds via iridium photocatalyzed intramolecular [2+2] photocycloaddition, allowing the synthesis of a variety of tetrahydrocyclobuta[c]quinolin-3(1H)-ones with high molecular complexity.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Physical
Weiyang Xue, Bin Gu, Huiling Wu, Mengyang Liu, Songbo He, Jingmei Li, Xin Rong, Chenglin Sun
Summary: A batch one-pot cascade approach using a bifunctional Pd/ZrO2 catalyst was developed for the synthesis of 2-alkyl cycloketones, achieving high conversion and yield at mild temperature. The catalyst showed slight deactivation after 10 cycles of reuse, but its performance was completely recovered after an oxidative regeneration.
APPLIED CATALYSIS A-GENERAL
(2021)
Article
Chemistry, Multidisciplinary
Zhen Liu, Zi-Yang Qin, Ledong Zhu, Soumitra Athavale, Arkajyoti Sengupta, Zhi-Jun Jia, Marc Garcia-Borras, K. N. Houk, Frances H. Arnold
Summary: Propargyl amines are versatile synthetic intermediates with numerous applications in the pharmaceutical industry. An enzymatic platform for enantioselective propargylic amination of alkynes using a hydroxylamine derivative as the nitrene precursor was developed in this study. The biocatalytic process showed high efficiency and selectivity, making it a promising approach for industrial applications.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Penang Dorjay Lama, Latchipatula Bhaskara Rao, Chinnabattigalla Sreenivasulu, Dakoju Ravi Kishore, Gedu Satyanarayana
Summary: An efficient method for the synthesis of alkyl benzoyl indanones was developed using intermolecular Heck coupling, intramolecular condensation, and alkylation, showing good substrate scope and enabling the synthesis of diverse products. Significantly, this protocol successfully utilized a single-column purification technique.
Article
Chemistry, Multidisciplinary
Emilia J. Virtanen, Siiri Peramaki, Kaisa Helttunen, Ari Vaisanen, Jani O. Moilanen
Summary: This study investigates six simple water-soluble aminobis(phosphonate) ligands as precipitating agents for rare earth elements, thorium, and uranium, achieving efficient separation with high separation factors. The ligands also demonstrate improved separation efficiency for adjacent lanthanoids compared to traditional precipitation agents, while enabling the recovery of precipitated metals without decomposition for potential recycling in the separation process.
Article
Chemistry, Applied
Abdolkarim Zare, Fatemeh Monfared, Seyed Sajad Sajadikhah
Summary: A novel organic-inorganic hybrid salt catalyst was prepared and characterized, showing high catalytic activity for the synthesis of N,N'-alkylidene bisamides under solvent-free conditions. The catalyst demonstrated superior performance compared to other catalysts in terms of yield, time, and reaction conditions.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Abdolkarim Zare, Jaleh Atashrooz, Mohammad Mehdi Eskandari
Summary: The nanorod-structured organic-inorganic hybrid material N-[SPIS][TFA] has been successfully utilized as a highly efficient, dual-functional, and recoverable catalyst for the solvent-free synthesis of 3,3'-(arylmethylene)-bis(2-hydroxynaphthoquinone) derivatives in short reaction times and high yields.
RESEARCH ON CHEMICAL INTERMEDIATES
(2021)
Article
Chemistry, Inorganic & Nuclear
Abdolkarim Zare, Manije Dianat
Summary: A highly efficient and green protocol has been developed for the synthesis of pyrimido[4,5-b]quinolines, utilizing a one-pot multicomponent reaction with high yields and short reaction times under solvent-free conditions. This protocol surpasses many others in terms of reaction times, yields, conditions, temperature, and catalyst amount.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Zhale Atashrouz, Esmael Rostami, Abdolkarim Zare
Summary: Chitosan and functionalized graphene oxide nanocomposite was utilized as an efficient and sustainable catalyst for the production of bis-coumarins under solvent-free conditions. The nanocomposite showed superior properties such as non-toxicity, environmental compatibility, simplicity in operation, thermal stability, and recyclability compared to previous reported catalysts.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Engineering, Chemical
Mehrab Valizadehderakhshan, Masoud Kazem-Rostami, Abolghasem Shahbazi, Mahsa Azami, Arnab Bhowmik, Lijun Wang
Summary: This work describes the process of stripping and refining CBD from hemp extracts using a WFMD system. By optimizing process conditions, high concentrations of CBD can be obtained.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Masoud Kazem-Rostami, Angel Orte, Ana M. Ortuno, Arthur H. G. David, Indranil Roy, Delia Miguel, Amine Garci, Carlos M. Cruz, Charlotte L. Stern, Juan M. Cuerva, J. Fraser Stoddart
Summary: In this study, the chirality transfer from a chiral host to an encapsulated achiral fluorophore has been achieved, resulting in specific photophysical and chiroptical properties.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Abdolkarim Zare, Alireza Kohzadian, Hossein Filian, Mariam Sadat Ghoreishi Nezhad, Amirali Karami
Summary: Highly efficient protocols for the production of pyrido[2,3-d:6,5-d']dipyrimidine and bis(pyrazolyl)methane derivatives using an acid ionic liquid [Et3N-SO3H][MeSO3] have been reported, demonstrating its superiority over other catalysts.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Chemistry, Multidisciplinary
Karam B. Idrees, Zhao Li, Haomiao Xie, Kent O. Kirlikovali, Masoud Kazem-Rostami, Xingjie Wang, Xijun Wang, Tzu-Yi Tai, Timur Islamoglu, J. Fraser Stoddart, Randall Q. Snurr, Omar K. Farha
Summary: Industrial-scale thermal separation processes contribute to the increase in carbon dioxide emissions. Porous materials, like metal-organic frameworks (MOFs), can potentially reduce these emissions by achieving nonthermal chemical separations through the physical adsorption of target species. This study focuses on the synthesis of channel-based MOFs NU-2000 and NU-2001, which can separate industrially relevant xylene isomers under ambient conditions due to sub-angstrom size differences. By increasing the linker dimensionality from 2D to 3D, precise control of MOF pore size and aperture can be achieved, independent of linker orientation.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Amine Garci, Jacob A. Weber, Ryan M. Young, Masoud Kazem-Rostami, Marco Ovalle, Yassine Beldjoudi, Ahmet Atilgan, Youn Jue Bae, Wenqi Liu, Leighton O. Jones, Charlotte L. Stern, George C. Schatz, Omar K. Farha, Michael R. Wasielewski, J. Fraser Stoddart
Summary: In this study, an approach to engineer the triplet excited states of aromatic chromophores by incorporating pyrene into mechanically interlocked molecules is described. The synthesized compounds demonstrate excellent catalytic activity in photo-oxidation reactions.
Article
Chemistry, Multidisciplinary
Wei Gong, Masoud Kazem-Rostami, Florencia A. Son, Shengyi Su, Kira M. Fahy, Haomiao Xie, Timur Islamoglu, Yan Liu, J. Fraser Stoddart, Yong Cui, Omar K. Farha
Summary: This study investigates the application of Troger's base (TB) and its derivatives in metal-organic framework (MOF) solids. The degree of derivatization reaction can be controlled in both solution and MOF systems, resulting in different topologies of Zr-MOFs. In addition, a novel water-induced formylation process and a highly effective catalyst for detoxification were discovered.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Chuang Li, Masoud Kazem-Rostami, James S. W. Seale, Shuailong Zhou, Samuel I. Stupp
Summary: This study designs a polymerizable bisazobenzene-based molecular photoswitch that can drive large-scale volume change and deformation when incorporated into polymer networks. These photoswitchable hydrogels mimic biological motions such as muscular contraction and light-driven bending, and can be used to tune macroscopic properties. This work provides a platform to investigate the relationship between molecular motion and macroscopic actuation.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Wei Gong, Masoud Kazem-Rostami, Florencia A. Son, Shengyi Su, Kira M. Fahy, Haomiao Xie, Timur Islamoglu, Yan Liu, J. Fraser Stoddart, Yong Cui, Omar K. Farha
Summary: The study focuses on the strap elimination of a carboxylate-carrying TB in solution and Zr(IV)-based MOFs, revealing different reactions depending on solvent used. In the MOF synthetic system, the derivatization process is topology-guided and dependent on local acid concentration, resulting in the formation of Zr-MOFs with different topologies. Additionally, a novel post-synthetically water-induced in situ linker formylation process was discovered in one of the MOFs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Masoud Kazem-Rostami
Summary: This study utilizes Troger's base analogs (TBAs) to design chiral macrocycles called Trogerophanes, which possess unique bent structures and stereogenic amine groups. These chiral donor macrocycles are mechanically interlocked with an electron-deficient macrocycle, resulting in the generation of a charge-transfer absorption band and the amplification of chiroptical properties. The study also demonstrates the discriminatory interactions of TBAs with chiral acids and their application in a photocatalytic oxidation process.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Indranil Roy, Austin M. Evans, Partha Jyoti Das, Mohamed Ateia, Matthew R. Ryder, Leighton O. Jones, Masoud Kazem-Rostami, Subhadip Goswami, Yassine Beldjoudi, Dengke Shen, George C. Schatz, Joseph T. Hupp, William R. Dichtel, J. Fraser Stoddart
Summary: A cyclophane-based 2DP with excellent crystalline porous properties was successfully synthesized at a liquid-liquid interface using click chemistry. The 2DP exhibited outstanding rejection performance for a dye when used as the active layer in nanofiltration membranes.
CELL REPORTS PHYSICAL SCIENCE
(2022)
Article
Chemistry, Physical
Marziyeh Barzegar, Abdolkarim Zare, Aysoda Ghobadpoor, Manije Dianat
Summary: A novel organic-inorganic hybrid magnetic nanomaterial was synthesized and characterized using various analytical techniques. It was used as a recyclable catalyst for the solvent-free synthesis of bis-coumarins. Based on its dual-functional catalytic activity, a plausible mechanism for the reaction was proposed.
IRANIAN JOURNAL OF CATALYSIS
(2022)
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
Article
Chemistry, Organic
Mikhail Kozlov, Alexey Tyurin, Andrey Dmitrenok, Vyacheslav Rusak, Aleksander Fedorov, Igor Zavarzin, Yulia Volkova
Summary: This study presents a novel and practical synthesis method for phosphorus-substituted 1,3,4-thiadiazolines using phosphorylthioformic acid hydrazides and ketones. The protocol demonstrates operational simplicity, availability of reagents, and tolerance towards different functional groups.
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.
