期刊
TETRAHEDRON
卷 69, 期 3, 页码 1217-1228出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.11.026
关键词
Heterocyclisation; Purine isosteres; Fused pyridines; Electron-excessive aminoheterocycles; Nitro-malonaldehyde
资金
- BMBF [03IS2081A]
- DAAD
The synthesis of 1-deazapurines and isosteres bearing the exocyclic nitrogen atom at position-1 was developed basing on the formal [3+3]-cyclization reaction of nitro-malonaldehyde with the set of electron-excessive aminoheterocycles. Through the functionalization of the purine-like scaffolds synthesized the diversity of compounds furnished in the possition-1 with aryl, alkinyl, and vinyl rests, were obtained. (C) 2012 Elsevier Ltd. All rights reserved.
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