期刊
TETRAHEDRON
卷 68, 期 1, 页码 226-237出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.10.060
关键词
beta-Phosphono malonates; 2-Amino-4H-chromen-4-ylphosphonate; Ethylenediamine diacetate; Three-component reactions
资金
- Ministry of Knowledge Economy (MKE) [RTI04-01-04]
- National Research Foundation of Korea [과C6B1910] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
One-pot three-component reactions of arylaldehyde or salicylaldehyde with malononitrile (or ethyl-cyanoacetate) and triethyl phosphite are carried out in the presence of ethylenediamine diacetate (EDDA) as a catalyst for the synthesis of biologically interesting beta-phosphono malonates and 2-amino-4H-chromen-4-ylphosphonate derivatives. The value of this method lies in its mild reaction catalyst and conditions, good yields, and ease of handling. (C) 2011 Elsevier Ltd. All rights reserved.
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