期刊
TETRAHEDRON
卷 67, 期 27-28, 页码 5046-5053出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2011.03.115
关键词
Propargylic substitution; Tetrahydropyrans; Morpholines; Dioxanes; Sulfamates; Platinum catalysis
资金
- Robert A. Welch Foundation [I-1422]
- Reata Pharmaceuticals
- NIH [CA90349]
We report a Pt(II)-catalyzed cyclization of nucleophile-tethered propargylic acetates yielding substituted heterocycles containing multiple heteroatoms including morpholines, dioxanes, and sulfamates with high cis-selectivity. (C) 2011 Elsevier Ltd. All rights reserved.
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