Enantioselective synthesis of martinelline chiral core and its diastereomer using asymmetric tandem Michael-aldol reaction

The martinelline chiral core 3 and its disastereomer were synthesized by using the asymmetric tandem Michael-aldol reaction as the key step from 4-methyoxycarbonylanthranilaldehyde and the alpha,beta-unsatuarated aldehyde (C) 2008 Published by Elsevier Ltd.