Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice

Protective effects of Penthorum chinense Pursh against chronic ethanol-induced liver injury in mice

(2015) Yi-Wei Cao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Arsenic-mediated nephrotoxicity

(2015) Ma Ludivina Robles-Osorio et al.   RENAL FAILURE

Lutein Has a Protective Effect on Hepatotoxicity Induced by Arsenic via Nrf2 Signaling

(2015) Shugang Li et al.   Biomed Research International

Acute arsenic treatment alters arachidonic acid and its associated metabolite levels in the brain of C57Bl/6 mice

(2014) Anwar Anwar-Mohamed et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Protective effect of dietary flaxseed oil on arsenic-induced nephrotoxicity and oxidative damage in rat kidney

(2014) Sana Rizwan et al.   FOOD AND CHEMICAL TOXICOLOGY

Trivalent methylated arsenic metabolites induce apoptosis in human myeloid leukemic HL-60 cells through generation of reactive oxygen species

(2014) Kanwal Rehman et al.   Metallomics

Critical role of cellular glutathione homeostasis for trivalent inorganic arsenite-induced oxidative damage in human bronchial epithelial cells

(2014) Xuejun Jiang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Atorvastatin ameliorates arsenic-induced hypertension and enhancement of vascular redox signaling in rats

(2014) Thengumpallil Sasindran Sarath et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effect of Selenomethionine Supplementation in Food on the Excretion and Toxicity of Arsenic Exposure in Female Mice

(2013) Miriam Rodríguez-Sosa et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion

(2013) Shuang Gao et al.   FOOD AND CHEMICAL TOXICOLOGY

Activation of the Nrf2 Pathway by Inorganic Arsenic in Human Hepatocytes and the Role of Transcriptional Repressor Bach1

(2013) Dan Liu et al.   Oxidative Medicine and Cellular Longevity

Cross-Regulations among NRFs and KEAP1 and Effects of their Silencing on Arsenic-Induced Antioxidant Response and Cytotoxicity in Human Keratinocytes

(2012) Rui Zhao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Glutathione, glutathione S-transferase, and glutathione conjugates, complementary markers of oxidative stress in aquatic biota

(2012) Jocelyne Hellou et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Arsenic-Mediated Activation of the Nrf2-Keap1 Antioxidant Pathway

(2012) Alexandria Lau et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism

(2012) Yoichiro Mitsuishi et al.   Frontiers in Oncology

Opposite effects of arsenic trioxide on the Nrf2 pathway in oral squamous cell carcinoma in vitro and in vivo

(2011) Xinyan Zhang et al.   CANCER LETTERS

The association between total urinary arsenic concentration and renal dysfunction in a community-based population from central Taiwan

(2011) Jein-Wen Chen et al.   CHEMOSPHERE

Acetaminophen increases the risk of arsenic-mediated development of hepatic damage in rats by enhancing redox-signaling mechanism

(2011) Chhaya Rani Majhi et al.   ENVIRONMENTAL TOXICOLOGY

Sodium arsenite induced reactive oxygen species generation, nuclear factor (erythroid-2 related) factor 2 activation, heme oxygenase-1 expression, and glutathione elevation in Chang human hepatocytes

(2011) Bing Li et al.   ENVIRONMENTAL TOXICOLOGY

Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer

(2011) Constance Lay Lay Saw et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Effects of low-level arsenic exposure on urinary N-acetyl-β-D-glucosaminidase activity

(2011) S-Y Eom et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Arsenic Exposure and Toxicology: A Historical Perspective

(2011) Michael F. Hughes et al.   TOXICOLOGICAL SCIENCES

Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells

(2010) Yumi Abiko et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Arsenic induces mitochondria-dependent apoptosis by reactive oxygen species generation rather than glutathione depletion in Chang human hepatocytes

(2009) Yi Wang et al.   ARCHIVES OF TOXICOLOGY

Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: Contribution of NADPH oxidase

(2009) Karen L. Cooper et al.   FREE RADICAL BIOLOGY AND MEDICINE

Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line

(2009) S. M. Matulis et al.   MOLECULAR CANCER THERAPEUTICS

Nrf2 protects against As(III)-induced damage in mouse liver and bladder

(2009) Tao Jiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Liver is a Target of Arsenic Carcinogenesis

(2008) Jie Liu et al.   TOXICOLOGICAL SCIENCES

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction

(2008) Xiao-Jun Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY