期刊
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
卷 9, 期 6, 页码 597-602出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/153303461000900608
关键词
Stereotactic radiosurgery; Microsurgery; Brain metastases; Whole-Brain Radiation therapy
类别
There is a growing interest in adjuvant radiosurgery following resection of hematogenous brain metastases. We have identified 12 series reporting on a total of 480 patients treated to a tumor bed following microsurgery. These cases fall into 3 paradigms: adjuvant radiosurgery as an alternative to whole-brain radiotherapy (WBRT), radiosurgery as an intensification of adjuvant WBRT and adjuvant radiosurgery for patients having failed prior WBRT. For these paradigms the reported crude local control rates are 79%, 92% and 95%, respectively. The procedure appears well tolerate with approximately a 5% risk of late radiation necrosis. Prospective data is lagging behind clinical practice and plans for prospective trials are discussed.
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