Article
Chemistry, Analytical
D. Sai Krishna, K. Madhavi, N. N. Meeravali, A. C. Sahayam
Summary: A rapid and highly sensitive vesicle mediated dispersive liquid-liquid microextraction procedure has been developed for the determination of parts per quadrillion level of beryllium in seawater and air filter samples. The method uses anionic vesicular surfactant and chelating agents to selectively extract beryllium, achieving excellent detection limits and recoveries across a range of sample types.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Valfredo Azevedo Lemos, Jeferson Alves Barreto, Luana Bastos Santos, Rosivan dos Santos de Assis, Cleber Galvao Novaes, Ricardo J. Cassella
Summary: Dispersive liquid-liquid microextraction (DLLME) is widely used for the separation and preconcentration of various chemical species, with some systems using a syringe as an extraction environment. This review discusses methods utilizing this approach, critical aspects like dispersion promotion, analytical characteristics, and the pros and cons of the methods, as well as future trends in in-syringe microextraction systems.
Review
Chemistry, Analytical
Idaira Pacheco-Fernandez, Raul Gonzalez-Martin, Francisca A. e Silva, Mara G. Freire, Veronica Pino
Summary: The successful mode of liquid-phase microextraction (LPME) is dispersive liquid-liquid microextraction (DLLME), with advances focused on utilizing green, smart, and tunable materials as extraction solvents to enhance sustainability and efficiency. Hydrophilic media are considered a promising alternative for improving mass transfer and extraction efficiency.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Qian Li, Kunxia Ji, Ninan Tang, Yueping Li, Xiaohong Gu, Kaijie Tang
Summary: A simple, rapid, and eco-friendly vortex-ultrasonic assisted dispersive liquid-liquid microextraction method was developed for the extraction of seven sulfonamides in fish samples using a hydrophobic deep eutectic solvent. The method exhibited excellent extraction and separation effects, with high recoveries and good precision and accuracy.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Vasagee Elencovan, Noorfatimah Yahaya, Nozlena Abdul Samad, Nur Nadhirah Mohamad Zain
Summary: A vortex-assisted surfactant enhanced emulsification liquid-liquid microextraction method based on non-ionic silicone surfactant was successfully developed for the determination of organophosphorus pesticides in food samples. This method is convenient, rapid, and environmentally friendly, with satisfactory recovery values for the target analytes.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Analytical
Yinghe Ji, Min Zhao, Anwen Li, Longshan Zhao
Summary: In this study, a deep eutectic solvent (DES) based on DL-lactic acid and trioctylmethylammonium chloride was used with ultrasonic-assisted dispersive liquid-liquid microextraction (UA-DLLME) for monitoring trace levels of Cd and As in wine samples. The method showed good linear relationships, low detection limits, and reliable accuracy and precision, providing practical value for analyzing heavy metal residues in wine and complex food matrices.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Yixiao Wang, Jinhua Li, Ling Ji, Lingxin Chen
Summary: Residues and abuse of antibiotics have posed serious threats to ecological balance and human health. Determining antibiotics levels is difficult due to their low levels and multiple categories. Appropriate sample pretreatment is necessary to enrich trace amounts of antibiotics and eliminate matrix interference before chromatographic analysis. Dispersive liquid-liquid microextraction (DLLME) is an ideal pretreatment technique due to its simplicity, effectiveness, and low consumption. In this study, ultrasonic-assisted DLLME (UA-DLLME) was developed for the simultaneous extraction of seven sulfonamides antibiotics in environmental water and seafood samples. The UA-DLLME-HPLC method showed promising potential for multiresidue analysis of antibiotics.
Article
Biochemical Research Methods
Mohamed A. Abdelaziz, Fotouh R. Mansour, Neil D. Danielson
Summary: A hydrophobic gadolinium-based magnetic ionic liquid was studied as an extraction solvent in DLLME for the first time, showing higher extraction efficiency than iron or manganese analogues, leading to improved sensitivity and reproducibility of the method, along with a reduced analysis time.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
Monireh Shahvalinia, Arash Larki, Kamal Ghanemi
Summary: In this study, a simple and cost-effective method based on UA-DLLME and smartphone colorimetric measurement was introduced for the separation and determination of TCS in contaminated waters. By optimizing various experimental parameters and considering their effects, this method can accurately measure TCS in a wide concentration range and provides satisfactory results in multiple water and wastewater samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemistry & Molecular Biology
Bharti Jain, Rajeev Jain, Prashant Kumar Jaiswal, Torki Zughaibi, Tanvi Sharma, Abuzar Kabir, Ritu Singh, Shweta Sharma
Summary: A green, fast, high-sample-throughput, non-instrumental, and affordable analytical method based on surfactant-assisted dispersive liquid-liquid microextraction (SA-DLLME) combined with thin-layer chromatography-digital image colourimetry (TLC-DIC) was proposed for determining favipiravir in biological and pharmaceutical samples. The method showed good linear range, low LOD and LOQ, and close agreement with HPLC-UV analysis results. The proposed methodology is green in nature and can be applied in resource-limited laboratories during the COVID-19 pandemic.
Article
Biophysics
Yan Zeng, Peng Qi, Yingwen Wang, Chao Chen, Dun Zhang
Summary: This study developed a multifunctional platform based on DNA Pom-Pom nanostructure for detection and inactivation of pathogenic bacteria. The platform showed excellent selectivity and ultra-sensitive detection limit, with negligible cytotoxicity to targets.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Reyla A. S. Dias, Eliane R. Sousa, Gilmar S. Silva, Lanna K. Silva, Arlan S. Freitas, Diana L. D. Lima, Erika M. L. Sousa
Summary: This study developed an HPLC-FLD methodology for the separation of fluoroquinolones and optimized the DLLME process for clean-up and preconcentration of enrofloxacin in water samples. The method showed successful results in samples with low salinity content.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Manufacturing
Wei Meng, Hongmei Li, Kaiqing Wang, Yanqiu Cao
Summary: An ultrasonic-assisted dispersive liquid-liquid microextraction method was developed for the simultaneous detection of four bisphenols in plastic packaging beverages. The method showed good recoveries and stability in spiked water solution and real honey samples. It was successfully applied to detect the four bisphenols in plastic packaging drinking water, soda water, and honey samples.
PACKAGING TECHNOLOGY AND SCIENCE
(2022)
Article
Chemistry, Analytical
Irina Timofeeva, Kira Stepanova, Andrey Bulatov
Summary: The new automated microextraction method demonstrated efficient extraction of polycyclic aromatic hydrocarbons in tea infusion with fast sample processing speed and no need for centrifugation.
Article
Chemistry, Applied
Malek Hassan, Furkan Uzcan, Usama Alshana, Mustafa Soylak
Summary: A novel method combining switchable-hydrophilicity liquid-liquid microextraction and magnetic nanoparticle-based dispersive solid-phase microextraction was proposed for the determination of erythrosine using UV/Vis spectrophotometry. The method showed excellent analytical performance with high sensitivity, low detection limits, and good reproducibility, making it suitable for the extraction and determination of erythrosine in food and consumer products.
Article
Chemistry, Applied
Hani Nasser Abdelhamid, Sherief A. Al Kiey, Walid Sharmoukh
Summary: Hybrid nanomaterials with dye encapsulated zeolitic imidazolate frameworks were synthesized and used as precursors for zinc oxide embedded nitrogen-doped carbon. The resulting ZnO@N-doped C exhibited high capacitance and excellent cycling stability, retaining 87.7% of the initial capacitance after 1000 galvanostatic charge-discharge cycles. The presence of a guest molecule like RhB significantly improved the capacitance of the carbonized ZIF-8 materials.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Review
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid, Aji P. Mathew
Summary: Cellulose-MOFs (CelloMOFs) are hybrid materials that combine cellulosic materials with metal-organic frameworks, offering a range of properties for applications in water remediation, air purification, gas storage, sensing/biosensing, and biomedicine. Their potential includes efficient adsorption for removing contaminants in water, catalytic applications for organic pollutants, air purification by removing greenhouse gases, and biomedical applications such as antibacterial and drug delivery. This review provides a synthesis, characterization, and overview of the applications of CelloMOFs materials, highlighting challenges and future prospects for researchers and scientists.
COORDINATION CHEMISTRY REVIEWS
(2022)
Review
Chemistry, Applied
Hani Nasser Abdelhamid
Summary: In this article, the authors review the application of ZIF-based materials for CO2 removal via adsorption and catalysis. Various reaction types and recent membrane technologies are highlighted. The prospects for industrial applications and commercialization of ZIF-based materials are also briefly discussed.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Hani Nasser Abdelhamid, Aji P. Mathew
Summary: This article reviews the applications of cellulose in the field of biomedicine, including antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. Cellulose-based materials possess customizable chemical, mechanical, and physical properties, making them suitable for biomedical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Veterinary Sciences
Ahmed Abdelrahiem Sadek, Mahmoud Abd-Elkareem, Hani Nasser Abdelhamid, Samia Moustafa, Kamal Hussein
Summary: The UiO-66 nanomaterial demonstrates excellent cytocompatibility and stimulates osteoblast functions, indicating its potential as a biomaterial for bone tissue engineering. In vivo experiments show enhanced osteogenesis and healing of bone defects, making UiO-66 a promising candidate for bone repair.
BMC VETERINARY RESEARCH
(2022)
Article
Chemistry, Applied
Mahmoud R. Saleh, Haitham M. El-Bery, Hani Nasser Abdelhamid
Summary: A wet-incipient impregnation method was used to synthesize hierarchical porous bimetallic (Co, Zn)-zeolitic imidazolate frameworks (ZIF-8)/TiO2 for efficient photocatalytic water splitting. Co@ZIF-8/TiO2 exhibited significantly higher photocatalytic efficiency than TiO2, with a hydrogen generation rate of 13 mmol·h(-1)·g(-1) and a 151-fold increase in catalytic performance. The hierarchical porous structure of Co@ZIF-8 facilitated charge transfer and provided efficient transport channels. This study demonstrates the potential of hierarchical porous metal-organic frameworks (MOFs) as support and promoter in photocatalytic applications of TiO2.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Applied
Hani Nasser Abdelhamid, Ghada Abd-Elmonsef Mahmoud
Summary: In this study, copper-based metal-organic frameworks (MOFs) were used to synthesize copper oxide (CuO) embedded into carbon (CuO@C), which displayed high antifungal activity against four economic postharvest plant pathogens. The CuO@C nanoparticles inhibited the growth of the fungal species and decreased their enzyme activity, reducing the potentiality of fruit disease. The successful formation of CuO@C nanoparticles was confirmed using various characterization techniques.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid
Summary: One-pot co-precipitation method for synthesizing microporous-mesoporous zeolitic imidazolate frameworks-8 (ZIF-8) crystals, using organic dyes as target molecules, was reported. The crystal growth involves an intermediate phase of zinc hydroxyl nitrate nanosheets, allowing the adsorption of the dyes. The materials showed potential for CO2 adsorption and ATP biosensing.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Walid Sharmoukh, Hani Nasser Abdelhamid
Summary: A metal-organic framework (MOF) of cerium (Ce) ions and 4,4 ',4 ''-nitrilotribenzoic acid linker was synthesized via a hydro thermal method. The Ce-MOF showed Fenton-like properties and displayed excellent catalytic oxidation activity for various organic compounds and water pollutants. It exhibited high efficiency in the oxidative degradation of dyes and could be recycled multiple times without significant loss of catalytic performance.
JOURNAL OF CLUSTER SCIENCE
(2023)
Article
Chemistry, Applied
Hani Nasser Abdelhamid
Summary: Metal-organic frameworks (MOFs) have shown great potential for industrial applications but current synthesis processes limit their use due to the powder form. A solvothermal method was used to grow copper-based MOFs onto a cotton textile, creating a material called CuBDC@Textile. CuBDC@Textile demonstrated excellent vapor sensing properties and high adsorption capacity for pyridine. This dual-functional material holds promise for further research on MOFs in textile applications.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Materials Science, Ceramics
Numa A. A. Althubiti, T. A. Taha, A. A. Azab, Hani Nasser Abdelhamid
Summary: The use of solid-state materials such as sodium borohydride for hydrogen storage and release can meet the requirements of the "Hydrogen Economy". This study investigated ZnO-based materials as catalysts for hydrogen release through the hydrolysis of NaBH4. The synthesis method produced nanocomposites consisting of ZnO-xTiO(2) and ZnO-xCeO(2) (x = 5 wt.% or 10 wt.%). Characterization techniques confirmed the phase purity and optical properties of the materials. The materials exhibited a high hydrogen generation rate and different activation energies.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Hani Nasser Abdelhamid, Islam M. A. Mekhemer, Abdel-Aal M. Gaber
Summary: In this study, benzimidazole derivatives were successfully synthesized through photocatalytic synthesis using a solid-state acid catalyst ZrOSO4@C. The reaction, which allowed for condensation and cyclization in a single vessel, resulted in high yield (77-98%) and high purity of the benzimidazoles. The catalyst showed improvement in the synthesis of various benzimidazole derivatives using a wide range of aromatic aldehydes and heterocycles.
MOLECULAR CATALYSIS
(2023)
Article
Energy & Fuels
Moushira Saleh, Hani Nasser Abdelhamid, Dina M. Fouad, Haitham M. El-Bery
Summary: The use of light radiation to split water into hydrogen gas has great potential for green hydrogen production. A comparative study was conducted on the photocatalytic activity of TiO2 nanocomposites with two co-catalysts, Pt or Cu nanocrystals, using different synthesis methods. The study found that the deposition technique of the co-catalyst has a significant influence on the efficiency of photocatalysis for hydrogen production.
Article
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid, Sahar Sultan, Aji P. Mathew
Summary: 3D printing of cellulose/leaf-like zeolitic imidazolate frameworks (CelloZIF-L) allows for the creation of structures with high adsorption efficiency, capable of adsorbing carbon dioxide and heavy metals.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Dimitrios Georgouvelas, Hani Nasser Abdelhamid, Ulrica Edlund, Aji P. Mathew
Summary: In this study, nanocellulose/alginate composite hydrogel beads were successfully prepared and modified with in situ TEMPO-mediated oxidation. The modified beads exhibited improved adsorption efficiency and water flux, making them promising candidates for large-volume, high flux water treatment.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
