Article
Chemistry, Analytical
Jiaxin Guo, Changrui Feng, Zi Liu, Baoxian Ye, Gaiping Li, Lina Zou
Summary: A label-free electrochemical biosensor for DNA assay was constructed using a novel structural DNA nanotweezer (DNT) coupled with split G-quadruplex. The biosensor showed high sensitivity, low detection limit, and ease of operation, contributing to improved stability and reproducibility in detecting circulating tumor DNA.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biochemistry & Molecular Biology
Zhongyuan Deng, Yudong Ren, Lina Guo, Xingcheng Xie, Lixiang Wang, Xianchun Li
Summary: In this study, G-quadruplex (G4) motifs were identified in the genome of Spodoptera frugiperda, and it was found that they were enriched in genic regions, particularly in the upstream regions of start codons. The G4 structures were more frequently present in the promoters of P450 and CarE gene families. Furthermore, the G4 ligand N-methyl mesoporphyrin IX (NMM) was shown to decrease P450 protein activity in larval midgut tissue, and it had synergistic effects with pesticides on toxicity. These findings suggest that G4 motifs could serve as a potential target for pest control.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Spectroscopy
Dilan Guner, Berke Bilgenur Sener, Ceren Bayrac
Summary: Auramine o (AO) is a synthetic dye used in paper and textile industries. Although it has been banned as a food additive in many countries, it is still illegally used in certain food products and pharmaceuticals. Monitoring the presence of AO in food products is important to minimize health risks. This study developed a simple, sensitive, and selective label-free detection method based on G-quadruplex for AO. The method showed high specificity for AO and was successfully applied to detect AO in pasta, bulgur, and curry powder.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Veterinary Sciences
Ying Wang, Rong Li, Yang Zhang, Weida Zhang, Sishun Hu, Zili Li
Summary: A visual detection method based on CRISPR-Cas12a has been developed for highly sensitive detection of ASFV and PCV2. This method is simple, convenient, and does not require instruments or power, making it suitable for field use.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Chemistry, Applied
Yanping Wu, Yachen Shi, Sha Deng, Chengyong Wu, Ruijie Deng, Guiping He, Mi Zhou, Kai Zhong, Hong Gao
Summary: The study introduced a unique aptamer probe construction method for label-free and ratiometric detection of lead in tea, showing high specificity and accuracy. The probe design utilizes dual fluorescent signal outputs under single-wavelength excitation for Pb2+ recognition, outperforming single fluorescent reporter-based analyses.
Article
Chemistry, Analytical
Zheng Chen, Feifeng Lin, Jiahua Liu, Lijuan Ke, Jie Wang
Summary: This study developed a binary C-rich functionalized palindromic hairpin probe (BC-FPHP) for amplifying miRNA-21, a common ovarian cancer biomarker, without the need for additional probes. The system is smartly designed with self-priming, self-templating, and self-amplifying capabilities, making it a simple, low-cost, and user-friendly platform for sensitive and specific detection. The BC-FPHP based amplification system has shown successful detection of miRNA-21 in diluted human serum samples, suggesting great potential in early ovarian cancer screening.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemical Research Methods
Ying Yan, Tingting Hu, Yukang Fang, Xinying Xiang, Changbei Ma
Summary: A system utilizing DNA chains and fluorescence signal was proposed to detect the concentration of miRNA-21. The method showed high sensitivity and a wide dynamic linear range.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Chemistry, Analytical
Xiaofei Liao, Nian Luo, Mengyan Li, Hao Fu, Li Zou
Summary: A novel label-free fluorescent biosensor for highly sensitive detection of bleomycin (BLM) was developed based on BLM-mediated inactivation of CRISPR-Cas12a and thioflavin T (ThT)-induced G-quadruplex formation. The biosensor exhibits high sensitivity and selectivity for detection of BLM in human serum samples, showing promise for BLM assay in biomedical research.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biophysics
Jianling Chen, Ji Yan, Qiumei Feng, Xiangmin Miao, Baoting Dou, Po Wang
Summary: The study proposed a label-free and enzyme-free fluorescence strategy based on CDs-SH for highly sensitive detection of miRNA using strand displaced amplification (SDA), which achieved a low limit of detection.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Huan Zeng, Shuqin Huang, Yunong Chen, Minshi Chen, Kaiyu He, Caili Fu, Qiang Wang, Fang Zhang, Liu Wang, Xiahong Xu
Summary: A sequence-specific visualization method based on loop-mediated isothermal amplification (LAMP) was developed for the detection of Salmonella in milk. The method used restriction endonuclease and nicking endonuclease to produce amplicons into single-stranded triggers, which further promoted the generation of a G-quadruplex by a DNA machine. The G-quadruplex DNAzyme possessed peroxidase-like activity and catalyzed the color development of ABTS as the readouts. The method demonstrated a sensitivity of 800 CFU/mL when observed with the naked eye and could detect Salmonella in milk within 1.5 h without the need for any sophisticated instrument.
Article
Chemistry, Analytical
Yuanxun Gong, Mengying Fu, Liqing Li, Yiming Yin, Qianli Tang, Wei Zhou, Guanqun Zhang, Xianjiu Liao, Fenglei Gao
Summary: In Parkinson's disease, the soluble alpha-synuclein oligomer is a reliable molecular biomarker. This study presents an innovative label-free and signal-on electrochemical apta-sensor for the quantification of alpha-syn oligomers. The tripedal DNA walkers triggered by alpha-syn oligomers outperformed common DNA walkers, leading to greater amplification efficiency. With the assistance of Mg2+-dependent DNAzyme, the tripedal DNA walkers could scissor DNA hairpins, generating enhanced current signals. The developed aptasensor demonstrated high sensitivity, anti-interference, and reproducibility, making it a promising tool for bioanalysis in complex biological environments.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biochemistry & Molecular Biology
Hijiri Hasegawa, Ikkei Sasaki, Kaori Tsukakoshi, Yue Ma, Kazuo Nagasawa, Shusuke Numata, Yuuki Inoue, Yeji Kim, Kazunori Ikebukuro
Summary: Genomic DNA methylation is studied as a potential biomarker for disease diagnosis. This study focuses on detecting CpG methylation in G4-forming oligonucleotides using G4 ligands, which show significant differences in fluorescence and chemiluminescence intensities between methylated and unmethylated DNAs. This research provides a new method for detecting DNA methylation based on structural changes using G4 ligands.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Environmental
Hao Wu, Jun Wu, Hongyong Wang, Yaling Liu, Guoqing Han, Pei Zou
Summary: This study demonstrated a label-free chemiluminescent aptasensor for sensitive detection of malathion using exonuclease-assisted dual signal amplification and G-quadruplex/hemin DNAzyme. The aptasensor showed an excellent linear response to malathion with a detection limit of 0.47 pM under optimal conditions, and successfully detected malathion in spiked food and traditional Chinese medicine samples.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Teerapong Jantarat, Surachada Chuaychob, Chongdee Thammakhet-Buranachai, Panote Thavarungkul, Proespichaya Kanatharana, Wisarut Srisintorn, Chittanon Buranachai
Summary: A label-free and sensitive fluorescent sensor based on Gquadruplex and Thioflavin T was developed for cisplatin detection in urine samples, showing high accuracy and precision. The sensor performance was influenced by various parameters including pH, buffer concentration, type and number of GQ, with a linear dynamic range of 10-500 nM. The sensor successfully quantified cisplatin levels with a limit of quantification at 10 nM.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Hua Gao, Miaomiao Feng, Feng Li, Kaixiang Zhang, Ting Zhang, Zifang Zhang, Chengyun Yang, Ruijie Deng, Junrong Zhang, Peng Jiang
Summary: In this study, a sensitive and label-free assay for diagnosing parasitic infections was developed using G-quadruplex DNAzyme as a reporter for CRISPR/Cas12. The assay showed a 5-fold increase in sensitivity for detecting L. donovani and eliminated the need for chemically labeled DNA probes.
Review
Food Science & Technology
Rong Du, Xiebingqing Yang, Ping Jin, Yahui Guo, Yuliang Cheng, Hang Yu, Yunfei Xie, He Qian, Weirong Yao
Summary: This review summarizes the recent 5-year research progress on the G-quadruplex (G4) structure in the detection of food contaminants. The article discusses the different applications of G4 as a recognition unit and a signal reporter, highlighting the current challenges and future directions, providing valuable insights for the field of food safety.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Agriculture, Multidisciplinary
Panting Sang, Gang Lu, Dongwei Yu, Xiaodong Song, Yahui Guo, Yunfei Xie, Weirong Yao, He Qian, Zhigang Hu
Summary: The study utilizes 8-17 DNAzyme as a substitute for horseradish peroxidase for simultaneous detection of small-molecule contaminants in milk, achieving multicolor signal output with lower detection limits. This approach may stimulate the development of ELISA in a new direction.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Food Science & Technology
Chang Liu, Yu Liu, Ciwan Wang, Yahui Guo, Yuliang Cheng, He Qian, Yong Zhao
Summary: This study demonstrates that lycopene bilosomes can alleviate kidney damage caused by a high-fat diet, and relieve nephritis and metabolic disorders by inhibiting the TLR4/MyD88 inflammatory pathway.
Article
Agriculture, Multidisciplinary
Chang Liu, Yahui Guo, Yuliang Cheng, He Qian
Summary: This study demonstrates that torularhodin-loaded bilosomes can improve hypercholesterolemia in mice fed a high-fat, high-cholesterol diet. Torularhodin alleviated weight gain, insulin resistance, and liver lipid accumulation. It also modulated inflammatory response and promoted amino acid metabolism.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Chang Liu, Mei Han, Fuqiang Lv, Yaobin Gao, Xiaoyun Wang, Xujiao Zhang, Yahui Guo, Yuliang Cheng, He Qian
Summary: The red stretcher bacterium Sporidiobolus pararoseus, a high producer of carotenoids, was found in various Chinese vinegar samples. The fungal carotenoid torularhodin exhibited strong antioxidant effects and protected against cellular inflammation in vitro and in a cell model. These effects were achieved by modulating the TLR4 pathway.
Review
Chemistry, Applied
Ruoyu Wang, Panting Sang, Yahui Guo, Ping Jin, Yuliang Cheng, Hang Yu, Yunfei Xie, Weirong Yao, He Qian
Summary: Cadmium (Cd) is a crucial industrial material used for electroplating and making rechargeable batteries, bringing convenience to mankind. However, Cd is also a harmful pollutant that enters the food chain and causes damage to human tissues and organs. Various technologies for removing Cd from food have been studied based on the binding mechanism between Cd and proteins.
Article
Biochemistry & Molecular Biology
Boru Guo, Aying Wen, Hang Yu, Yahui Guo, Yuliang Cheng, Yunfei Xie, He Qian, Weirong Yao
Summary: Mancozeb, a commonly used antifungal for fruit growth, can bind to the waxy components of fruits and has non-internal absorption. This study investigated the interaction between pesticide molecules and the waxy layer on grape surfaces and their impact on pesticide residues. Significant changes in the composition of the grape surface waxy layer were observed after soaking in a mancozeb solution, and molecular docking revealed hydrogen bonds and van der Waals forces between mancozeb and the waxy components. The presence or absence of wax affected the determination of mancozeb residues, with significantly lower deposition in grapes after dewaxing.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Xiaoyan Fu, Shaofeng Yuan, Fangwei Yang, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao
Summary: The interaction between boscalid and tannic acid was investigated using spectroscopic, thermodynamic, and computational chemistry methods. The results showed the formation of hydrogen bonds and hydrophobic interactions in the complex between boscalid and tannic acid. Additionally, the binding of boscalid to tannic acid significantly reduced the antioxidant activity of tannic acid. This study provides insights into the molecular mechanisms of the interaction between pesticide residues and food matrices, and informs the regulation of bound-state pesticide residues in food.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Food Science & Technology
Hongkang Zhu, Fanglin Shen, Xiaochen Wang, Yuliang Cheng, Yahui Guo, He Qian, Yu Liu
Summary: Research has found that salidroside (SA), an active compound derived from Rhodiola rosea, is widely used in healthcare foods. This study investigated the effects of SA on gut microbiota and energy metabolism during exercise in mice. The results showed that SA increased swimming time, respiratory enzymatic activities, and species diversity and abundance of gut bacteria, indicating its antifatigue effects.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Xiaotong Yang, Jie Yin, Yahui Guo, Hang Yu, Shaofeng Yuan, He Qian, Weirong Yao, Jiangfeng Song
Summary: This study combined low-intensity ultrasonic waves with the Lactobacillus plantarum fermentation method to optimize a technique for removing cadmium from rice. The technique achieved a high Cd removal rate of 67.05% within a short time (10 hours), addressing the long time requirement of traditional methods. Further analysis showed that the maximum adsorption capacity of Lactobacillus plantarum for Cd increased by 75% after ultrasonic intervention. Sensory evaluation and other experiments confirmed the feasibility of this method for actual rice production.
Article
Agriculture, Multidisciplinary
Shaofeng Yuan, Hang Yu, Yunfei Xie, Yahui Guo, Weirong Yao
Summary: The effect and mechanism of ultrasound on the biodegradation of profenofos by Lactiplantibacillus plantarum were investigated in this study. Ultrasound applied during the prelogarithmic phase of microbial growth significantly enhanced the biodegradation of profenofos. The key ultrasonic parameters were optimized using the response surface methodology, and the Holden model was used to describe the growth of L. plantarum and the biodegradation of profenofos. Under optimal ultrasonic conditions, the specific growth rate of L. plantarum and the specific degradation rate of profenofos were significantly increased compared to without sonication, attributed to the enhancement of phosphatase activity and the improvement of cell membrane permeability.
ACS AGRICULTURAL SCIENCE & TECHNOLOGY
(2023)
Review
Food Science & Technology
Shaofeng Yuan, Hang Yu, Yahui Guo, Yunfei Xie, Yuliang Cheng, He Qian, Weirong Yao
Summary: The extensive use of pesticides in agriculture leads to pesticide residues in food and feed, posing a significant threat to human health. Physical and chemical methods for pesticide removal are costly or prone to secondary contamination. Microorganisms, such as probiotics, have emerged as a promising alternative for pesticide elimination. This review examines the current research status on the use of probiotics for pesticide reduction, discussing the mechanisms involved, toxicity and potential health risks of degradation products, as well as strategies for enhancing probiotic detoxification.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Jie Yin, Kunfeng Liu, Shaofeng Yuan, Yahui Guo, Hang Yu, Yuliang Cheng, Yunfei Xie, He Qian, Weirong Yao
Summary: This research confirmed the presence of carbon dots (CDs) in breadcrumbs before frying and their significant changes after frying. The study found that the content and fluorescence quantum yield of CDs increased, while the size and N content decreased after frying. The interaction of CDs with human serum albumin (HSA) led to structural changes in HSA and the formation of CDs corona, which may have physiological significance.
Review
Nanoscience & Nanotechnology
Zhuoren Yang, Xiebingqing Yang, Yahui Guo, Hideya Kawasaki
Summary: This review analyzes the potential of gold nanoclusters (AuNCs) in cancer phototherapy, including photodynamic therapy (PDT), photothermal therapy (PTT), and combination therapy. It highlights the unique advantages, diverse application approaches, and promising prospects of AuNCs in phototherapy.
ACS APPLIED BIO MATERIALS
(2023)
Article
Nutrition & Dietetics
Cheng Wang, Hongkang Zhu, Yuliang Cheng, Yahui Guo, Yong Zhao, He Qian
Summary: This study investigates the potential role of Brassica rapa L. in modulating exercise-induced fatigue. The findings reveal that Brassica rapa L. exhibits significant antioxidant activity and effectively modulates physiological responses to fatigue. It influences gene expression related to energy metabolism and inflammation, and also maintains intestinal integrity. These findings highlight the potential therapeutic applications of Brassica rapa L. in managing prolonged exercise-induced fatigue.
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
