Flow-injection analysis systems with different detection devices and other related techniques for the in vitro and in vivo determination of dopamine as neurotransmitter. A review

Dopamine (DA) is one of the most important catecholamine neurotransmitters in the human central nervous system in the brain and plays a key role in the functioning of the renal, hormonal, and cardiovascular systems. Abnormal levels of dopamine are related to neurological disorders, such as schizophrenia and Parkinson's disease and the control and fluctuations of the amount of dopamine are extremely important in monitoring with analytical systems in the human brain. This review covers the attributes of flow-injection analysis systems with different detection devices and other related techniques for the in vitro and in vivo determination of dopamine as neurotransmitter and points out the advantages and disadvantages in the implementation thereof. (C) 2012 Elsevier B.V. All rights reserved.