Article
Chemistry, Analytical
Lanlan Li, Qirui Huang, Jing Xiao, Jiamin Feng, Shu Zhang, Hong Luo, Zhirong Zou, Xiaoli Xiong
Summary: In this study, Fe3O4 served as both an adsorbent and photocatalyst in the photochemical vapor generation-atomic fluorescence spectrometry (PVG-AFS) determination of Bi(III) after preconcentration. The effects of formic and acetic acid concentration, UV irradiation time, Fe3O4 concentration, and interferences from co-existing ions were investigated. Results showed that the AFS intensity was slightly enhanced by the mixed acid solution, but a significant enhancement was observed when Fe3O4 was used as a photocatalyst. Fe3O4 can decompose in the mixed acid solution, generating Fe3+ which acts as a sensitizer for improving Bi(III) efficiency. Under optimized conditions, the LOD of the proposed PVG-AFS system with or without preconcentration (5 mL sample) were 0.44 ng/mL and 0.07 ng/mL, respectively. The PVG-AFS system was successfully applied to the determination of water samples and demonstrated good accuracy and applicability with recoveries ranging from 94% to 104%.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yongchun Liu, Jie Zou, Bin Luo, Hairong Yu, Zhigang Zhao, Hui Xia
Summary: Using natural plant extracts as auxiliary matrix or photocatalysts can enhance the efficiency and sensitivity of photochemical vapor generation atomic fluorescence spectrometry for trace mercury determination, while reducing biological toxicity and secondary pollution. This green and sensitive method provides an experimental basis for expanding the photochemical vapor generation system.
MICROCHEMICAL JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Meihong Zhan, Weimin Gao, William Nguyen, Hongmei Yu, Eric Amador, Wei Chen
Summary: Triadic silica-supported polyhexamethylene guanidine@nano-hydroxyapatite (HAP) composites were prepared and used for solid phase extraction of Cr (VI) in a micro-column system, with its determination by flame atomic absorption spectrometry (FAAS). The results showed that the triadic silica-supported nano-HAP composites efficiently adsorbed Cr (VI) at pH 4.0-6.0, while almost no adsorption of Cr (III) occurred. The method exhibited good linearity, detection limit, and precision for Cr (VI) determination, and it was successfully applied to the analysis of chromium contents in cereal and water samples.
MATERIALS TODAY ADVANCES
(2022)
Article
Chemistry, Applied
Fernanda Garcia de Almeida, Milena do Prado Ferreira, Mariana Gava Segatelli, Alexandra Beal, Wilma Aparecida Spinosa, Fabio Antonio Suquila Cajamarca, Cesar Ricardo Teixeira Tarley
Summary: A solid phase preconcentration method for cobalt determination at trace levels was developed using a cross-linked polymer as an efficient adsorbent, achieving high sensitivity and recoveries ranging from 91-104% in different samples.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Chemistry, Analytical
Yaru Zhang, Xuefei Mao, Di Tian, Jixin Liu, Chunsheng Li
Summary: A novel method using low-cost miniaturized hydride generation optical emission spectrometry equipment coupled with an in situ dielectric barrier discharge trap was developed for the determination of As in edible seaweed samples. The method significantly improved the linear range and sensitivity, with a detection limit of 0.2 μg L-1. Application of the method to seaweed samples yielded a method detection limit of 0.25 mg kg(-1) with good accuracy and precision.
ANALYTICAL METHODS
(2021)
Article
Environmental Sciences
Kai-Qiang He, Xiao-Ru Zhang, Yuan-Peng Li, Xue-Lei Duan, Yan Li, Yang-Hong Jiang, Xiao-Dong Yuan, Ke-Gang Zhang, Chun-Gang Yuan
Summary: With the increasing strictness of environmental protection policies in China, coal-fired power plants have widely adopted air pollution control devices, especially selective catalytic reduction (SCR). This study successfully developed an on-line coupling system based on atomic fluorescence spectrometry (AFS) and a homemade chromatographic workstation to identify mercury (Hg) species through thermal programmed desorption (TPD). The main species in fly ash were HgCl2 and HgO, while in gypsum they were Hg2Cl2 and HgO. The study demonstrated that AFS coupled with TPD was an effective method to analyze Hg species in coal combustion by-products from power plants.
Article
Chemistry, Multidisciplinary
Abolghasem Zanganeh, Hamid Reza Ghasempour, Mohammad Kazem Koohi, Nasser Karimi
Summary: A novel functionalized magnetic metal-organic framework (MOF) was synthesized and applied for the extraction and determination of Hg(II) ions in food samples. The new material, modified with 1,3,4-Thiadiazole-2,5-dithiol chelator, exhibited high efficiency in separating and enriching Hg(II) ions. The optimized extraction conditions were determined using experimental design approach, and the elution step was performed using 0.7 mol L-1 HCl solution.
RESEARCH ON CHEMICAL INTERMEDIATES
(2023)
Article
Chemistry, Inorganic & Nuclear
Man Wang, Han-Shu Li, Xin Ding, Lizan Jiang, Pengyan Wu, Ruiting Zheng, Guoyue Bao, Guoliang Liu, Jian Wang
Summary: In this study, a luminescent porous organic network (PON) connected by imine linkages was successfully synthesized. The PON showed strong fluorescence in water and demonstrated high selectivity and sensitivity for the detection of Cr(vi) species (CrO42- and Cr2O72-) in a turn-off manner. The possible luminescence sensing mechanism and the adsorption capacity of Cr(vi) were also discussed in detail.
DALTON TRANSACTIONS
(2022)
Review
Chemistry, Analytical
Guanghui Niu, Alexander Knodel, Sebastian Burhenn, Sebastian Brandt, Joachim Franzke
Summary: The development of miniature, sensitive, high throughput, and in-situ analytical instruments using dielectric barrier discharge (DBD) has become a hot topic in modern analytical chemistry. DBD offers advantages such as easy operation, simple configuration, ambient working temperature and pressure, low power consumption, and miniature dimension. Its applications in analytical atomic spectrometry include serving as excitation or atomization sources in AES, AAS, and AFS, as well as functioning as a vapor generation system.
ANALYTICA CHIMICA ACTA
(2021)
Article
Environmental Sciences
Jasmina Sulejmanovic, Mustafa Memic, Elma Sehovic, Rasim Omanovic, Sabina Begic, Mirha Pazalja, Atifa Ajanovic, Ofaira Azhar, Farooq Sher
Summary: In this study, a simple and reliable preconcentration column method was developed for the determination of eight metallic ions in model solutions and real water samples. The column was filled with silica gel modified with vanadium(V) oxide as an efficient and economical adsorbent to remove metallic ions from liquid solutions.
Article
Chemistry, Applied
Zhenzhen Yao, Jixin Liu, Xuefei Mao, Guoying Chen, Zhihong Ma, Bingru Li
Summary: For the first time, separation and analysis of Hg2+ and methylmercury was achieved using in-line SPE-LC-AFS. The method was easy, compact, robust, and sensitive in mercury speciation analysis, ensuring food safety.
Article
Engineering, Electrical & Electronic
Chittatosh Pal, Subrata Majumder
Summary: This study demonstrates a label-free electrochemical sensor based on carboxylated MoS2 flakes functionalized with poly (Thymine), which can detect Hg2+ ions at extremely low concentrations in the aqueous medium. The sensor offers low detection limits, high selectivity, and good results in real samples.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2022)
Article
Spectroscopy
Joanna Dobrzynska, Marzena Dabrowska, Ryszard Dobrowolski, Kinga Morlo
Summary: Pt(IV) ion-imprinted thiocyanato-functionalized SBA-15 material (Pt(IV)S1) was used for preconcentration of Pt(IV) ions from digested geological samples before ETAAS determination. The ion-imprinted material showed high adsorption affinity and selectivity towards Pt(IV) ions. The proposed procedure achieved a high enrichment factor of 38 and a low limit of quantification of 0.079 mg kg-1.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Pharmacology & Pharmacy
Xiao Wu, Zeling Zhong, Kuangmin Lin, Xinhe Liu, Zhichao Wu, Zitian Liu, Yongming Li
Summary: This study compared the pharmacokinetics and urinary excretion of arsenic and mercury in rats after oral administration of realgar, cinnabar, and AGNHP. AGNHP reduced arsenic absorption and promoted urinary excretion, while increasing blood mercury absorption and reducing urinary excretion. No significant toxicity was observed in the clinical dose range.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Anna Mutschler, Vivian Stock, Lena Ebert, Emma M. Bjoerk, Kerstin Leopold, Mika Linden
Article
Biochemical Research Methods
Dominic Brucker, Kerstin Leopold
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2019)
Article
Multidisciplinary Sciences
A. J. Birchill, N. T. Hartner, K. Kunde, B. Siemering, C. Daniels, D. Gonzalez-Santana, A. Milne, S. J. Ussher, P. J. Worsfold, K. Leopold, S. C. Painter, M. C. Lohan
SCIENTIFIC REPORTS
(2019)
Article
Public, Environmental & Occupational Health
Veruscka Leso, Luca Fontana, Alessandro Marinaccio, Kerstin Leopold, Caterina Fanali, Donatella Lucchetti, Alessandro Sgambato, Ivo Iavicoli
TOXICOLOGY AND INDUSTRIAL HEALTH
(2019)
Article
Chemistry, Analytical
Maria Schlathauer, Jens Friedland, Mika Linden, Kerstin Leopold
MICROCHEMICAL JOURNAL
(2019)
Letter
Hematology
Naveen Kumar Tangudu, Dilay Yilmaz, Katharina Woerle, Andreas Gruber, Silvia Colucci, Kerstin Leopold, Martina U. Muckenthaler, Maja Vujic Spasic
Article
Biochemical Research Methods
Andreas Gruber, Riccarda Mueller, Alessa Wagner, Silvia Colucci, Maja Vujic Spasic, Kerstin Leopold
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Angela Gambelunghe, Stefano Giovagnoli, Alessandro Di Michele, Simona Boncompagni, Marco Dell'Omo, Kerstin Leopold, Ivo Iavicoli, Vincenzo Nicola Talesa, Cinzia Antognelli
Article
Chemistry, Multidisciplinary
Vivian Stock, Anna Mutschler, Mika Linden, Kerstin Leopold
Summary: This study presents a novel approach using photoactive titanium dioxide films with embedded gold nanoparticles (AuNP@TiO2 dipstick) for chemical-free sample preparation and mercury preconcentration. The method effectively overcomes the hindrance caused by humic matter in natural waters, resulting in high analytical sensitivity and accuracy in mercury detection.
Book Review
Biochemical Research Methods
Kerstin Leopold
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
Jens Friedland, Anja Brandt, Kerstin Leopold, Robert Guettel
Summary: This study combines experimental and computational modeling to achieve simultaneous sizing and quantification of gold nanoparticles. The simulation-assisted calibration method shows competitiveness and can reduce calibration time by up to 80%.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Biochemical Research Methods
Sebastian Hauser, Sophia Andres, Kerstin Leopold
Summary: This study presents an effective method for preparing sample suspensions for rapid TXRF analysis of large placental samples. The results show significant differences in the distribution of trace elements in placental tissue, indicating the necessity for more systematic investigation of non-homogeneous elements.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Paul Knoop, Dilay Yilmaz, Rossana Paganoni, Peter Steele-Perkins, Andreas Gruber, Banu Akdogan, Hans Zischka, Kerstin Leopold, Maja Vujic Spasic
Summary: Mutations in the HFE/Hfe gene cause Hereditary Hemochromatosis (HH), characterized by iron deposition. HFE acts in hepatocytes and myeloid cells to regulate iron homeostasis. However, HFE actions in liver-resident macrophages seem to be dispensable for cellular, hepatic, and systemic iron regulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Spectroscopy
Anja Brandt, Beatriz Gomez-Nieto, Jens Friedland, Robert Guettel, Kerstin Leopold
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2020)
Article
Chemistry, Analytical
Anja Brandt, Karin Kees, Kerstin Leopold
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2020)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).