Preparation of silver hexacyanoferrate nanoparticles and its application for the simultaneous determination of ascorbic acid, dopamine and uric acid

A silver hexacyanoferrate nanoparticles/carbon nanotubes modified glassy carbon electrode was fabricated and then successfully used for the simultaneous determination of ascorbic acid, dopamine and uric acid by cyclic voltammetry. A detailed investigation by transmission electron microscopy (TEM) and electrochemistry was performed in order to elucidate the preparation process and properties of the nanocomposites. The size of silver hexacyanoferrate nanoparticles was examined by TEM around 27 rim. Linear calibration plots were obtained over the range of 40 x 10(-6)-7.8 x 10(-5), 2.4 x 10(-6)-1.3 x 10(-4) and 20 x 10(-6)-1.5 x 10(-4) mol L(-1) with detection limits of 4.2 x 10(-7).1.4 x 10(-7) and 6.0 x 10(-8) mol L(-1) for ascorbic acid, dopamine and uric acid, respectively The practical analytical utilities of the modified electrode were demonstrated by the determination of ascorbic acid. dopamine and uric acid in urine and human blood serum samples. (C) 2009 Elsevier B.V. All rights reserved