Review
Chemistry, Analytical
Elnaz Bagheri, Legha Ansari, Khalil Abnous, Seyed Mohammad Taghdisi, Pouria Ramezani, Mohammad Ramezani, Mona Alibolandi
Summary: Traditional analytical methods are limited by high consumption of reagents, time, expensive equipment and complex sample preparation, creating a demand for simple, fast and sensitive procedures. Quantum dots and mesoporous silica nanoparticles have garnered attention for their unique properties and potential in sensor development, offering opportunities for the detection of a wide range of analytes.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2021)
Article
Biology
Ernest B. van der Wee, Jantina Fokkema, Chris L. Kennedy, Marc del Pozo, D. A. Matthijs de Winter, Peter N. A. Speets, Hans C. Gerritsen, Alfons van Blaaderen
Summary: This study introduces a single sample for calibrating STED and confocal microscopes, allowing calibration in three dimensions, alignment of laser beams, and measurement of PSF. The sample consists of refractive index matched colloidal crystal of specific structure, which can be used for improving the quality of microscopic images.
COMMUNICATIONS BIOLOGY
(2021)
Article
Chemistry, Physical
Drew Z. Spera, Indika U. Arachchige
Summary: Ge1-xSnx alloy nanocrystals exhibit composition-dependent energy gap tunability and enhanced light-matter interactions. By growing a silica layer on the surface of Ge1-xSnx, optical stability is improved and oxidation is inhibited. The Ge1-xSnx/SiO2 core/shell nanocrystals demonstrate robustness, oxidation resistance, and optical stability.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Spectroscopy
Yixuan Cui, Aoxuan Su, Jingying Feng, Weichong Dong, Junmei Li, Huan Wang, Xiaoyu Ni, Ye Jiang
Summary: A fluorescence probe based on CDs coated with silica MIPs was synthesized for selective and sensitive determination of CTZ. The method demonstrated a low detection limit, high recovery rates, and good specificity, making it suitable for the quantification of trace CTZ in biological samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemical Research Methods
Daniil D. Drozd, Nadezhda A. Byzova, Pavel S. Pidenko, Daria V. Tsyupka, Pavel D. Strokin, Olga A. Goryacheva, Anatoly V. Zherdev, Irina Yu. Goryacheva, Boris B. Dzantiev
Summary: A new bioanalytical labeling system based on alloyed quantum dots' photoluminescence quenching caused by an enzymatic reaction has been developed and tested. The use of alloyed luminescent QDs provides high sensitivity and the ability to vary the detecting time, leading to improved assay sensitivity.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Nan Li, Yan Jiang, Lei Gao, Zhongzhou Yi, Yunlong He, Fengrui Zhai, Kinnor Chattopadhyay
Summary: FeOOH quantum dots (QDs) are emerging as a promising material for the photodegradation of organic pollutants and the removal of dyes from aqueous solution. In this study, a one-pot microemulsion method was successfully developed to efficiently fabricate FeOOH QDs within 30 min. The FeOOH QDs exhibited a high BET surface area and a maximum adsorption capacity for methyl orange (MO), following the Langmuir isotherm. The adsorption performance of FeOOH QDs was found to be better in acidic solution and they showed good stability and reusability.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Acoustics
Reshma Kaimal, Victor Vinoth, Hector Valdes, Belqasem Aljafari, Sambandam Anandan, Amol Shrikrishna Salunke, Ramalinga Viswanathan Mangalaraja
Summary: A facile electrochemical method has been developed for glutathione sensing using novel glassy carbon electrode composed of graphene quantum dots (GQDs) embedded on amine-functionalized silica nanoparticles (SiNPs). The newly developed electrode exhibits a good response to glutathione with a wide linear range and a low detection limit, and it shows highly attractive electrocatalytic activity towards glutathione detection in neutral media. This electrode also provides outstanding selectivity, reproducibility, long-term stability, and can be used in the presence of interferences typically found in real sample analysis.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Fang Gao, Chang Lei, Yang Liu, Hao Song, Yueqi Kong, Jingjing Wan, Chengzhong Yu
Summary: This study investigates the impact of surface chemistry of dendritic mesoporous silica nanoparticles (DMSNs) on their enrichment of quantum dots (QDs) and signal amplification as label materials. The amino groups on DMSNs are found to benefit QD fluorescence preservation, while thiol groups increase QD loading capacity. Optimized DMSNs-QDs labels achieve high QD fluorescence preservation and loading capacity, enabling ultrasensitive detection of serum amyloid A (SAA).
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Yizhong Shen, Tingting Wu, Yuqi Wang, Shao-Lin Zhang, Xueli Zhao, Hong-Yuan Chen, Jing-Juan Xu
Summary: A novel ratiometric fluorescent method was developed to sensitively and specifically report Cathepsin B (CTSB) activity by integrating cancer-targeting recognition moiety and a large emission wavelength shift into a single matrix.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yue Zan, Lionel Salmon, Azzedine Bousseksou
Summary: SCO@SiO2 nanoparticles based on 1,2,4-triazole iron (II) coordination compounds were prepared using a reverse microemulsion technique. The thickness of the silica shell and the morphology of the nanoparticles were studied by adjusting the polar phase/surfactant ratio, TEOS precursor quantity, ammonia quantity, and reaction temperature. The controllable size and silica shell thickness of the nanoparticles open up possibilities for post-synthetic modifications. The evolution of spin crossover properties with morphological changes was investigated through variable temperature optical and magnetic measurements.
Article
Medicine, Research & Experimental
Rafaella B. L. Henrique, Rennan R. M. Lima, Camila A. P. Monteiro, Weslley F. Oliveira, Goreti Pereira, Paulo E. Cabral Filho, Adriana Fontes
Summary: Spheroids are three-dimensional multicellular microstructures that can replicate the complexity of the biological microenvironment and tumor architecture. Compared to traditional cell culture methods, spheroids provide more accurate results that resemble in vivo organisms. In addition, inorganic nanoparticles have been proven to be valuable tools for understanding biological processes and have potential applications in diagnostics and therapeutics. This review highlights the versatility of spheroids in studying biological interactions involving inorganic nanoparticles, including penetration profiles, toxicity evaluation, and therapeutical approaches.
Article
Chemistry, Multidisciplinary
Yonghong Song, Yueqiang Zhu, Kun Jiang, Xingyu Liu, Liang Dong, Dongdong Li, Sheng Chen, Hanye Xing, Xu Yan, Yang Lu, Xianzhu Yang, Junxia Wang, Yunjun Xu
Summary: Multifunctional magnet-fluorescent nanocomposites have wide applications in biomedical field. In this study, highly ferrimagnetic magnetic nanoparticles and ZnS/InP quantum dots were encapsulated in an amphiphilic block copolymer to obtain ferrimagnetic fluorescent micelles (FMFM) with uniform diameter and long-term stability. The FMFM showed excellent magnetic heating effect and magnetic resonance imaging capability, achieving improved magnetic hyperthermia therapy efficacy both in vitro and in vivo.
Article
Chemistry, Inorganic & Nuclear
Siraphat Jan Cheepborisutikul, Makoto Ogawa
Summary: A thin and homogeneous silica layer was successfully deposited on anatase particles through hydrolysis and condensation, leading to densification after heat treatment. Repeated coating and heating procedures were found to slow down the photocatalytic decomposition of methylene blue, with a significantly reduced decomposition rate constant achieved after three times of coating and heating.
INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Dmitry V. Korolev, Galina A. Shulmeyster, Natalia V. Evreinova, Maria S. Syrovatkina, Maria S. Istomina, Victor N. Postnov, Ilia V. Aleksandrov, Aleksandr S. Krasichkov, Michael M. Galagudza
Summary: This paper describes the synthesis of multilayer nanoparticles for the diagnosis and treatment of ischemic injuries. The nanoparticles consist of magnetite and silica, with quinacrine used as an anti-ischemic agent. The study involves surface modification, immobilization of quinacrine, and the formation of a chitosan coating to fix fluorophores and quantum dots as secondary radiation sources. The potential theranostic platform was tested in laboratory animals.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Organic
Shixian Cao, Pan Wang, Xi Zeng, Zhu Tao, Xin-Long Ni
Summary: The study utilized the cucurbituril host-guest chemistry to assist in the formation of carbon dots with tunable particle size and high fluorescence emission. By retaining the original rigid macrocyclic skeletons of the hosts during the fabrication process, the CDs obtained were characterized by high quality and unique properties, offering potential applications in biosensors and other fields.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Engineering, Civil
Lihua Li, Langling Qin, Henglin Xiao, Zhi Hu, Guofang Xu, Qiang Ma
Summary: This study investigated the effect of particle sizes and sand contents on the mechanical behavior of recycled construction and demolition (C&D) materials. The results showed that adding an appropriate amount of sand can improve the particle gradation and maximum dry density of the materials, as well as increase the overall strength of the specimens.
EUROPEAN JOURNAL OF ENVIRONMENTAL AND CIVIL ENGINEERING
(2023)
Article
Chemistry, Analytical
Xianshuang Meng, Shanshan Sun, Hua Bai, Qiang Ma
Summary: This study presents the first online coupling of matrix solid-phase dispersion (MSPD) to direct analysis in real time mass spectrometry (DART-MS) with solid-phase analytical derivatization (SPAD) using a graphene oxide nanosheets (GONs)-coated cotton swab. It demonstrates the high-throughput analysis of regulated chemicals in consumer products. The MSPD-DART-MS methodology was optimized and validated, achieving acceptable recovery, repeatability, and sensitivity for 32 target analytes. The developed protocol streamlines the entire analytical workflow, showing promising potential for high-throughput analysis of samples with complex matrices.
ANALYTICA CHIMICA ACTA
(2023)
Article
Engineering, Electrical & Electronic
Qi Wang, Wenchuan Wu, Bin Wang, Guannan Wang, Yanna Xi, Haitao Liu, Shu Wang, Jun Zhang
Summary: This paper proposes an asynchronous distributed algorithm for the coordinated operation problem between virtual power plants (VPPs) and distribution system operators (DSOs). The algorithm has reliable and fast convergence performance under communication uncertainties.
IEEE TRANSACTIONS ON POWER SYSTEMS
(2023)
Article
Biochemical Research Methods
Guoping Li, Jing Chen, Qing Yang, Xuexin Yang, Penglong Wang, Haimin Lei, Ma Mi, Qiang Ma
Summary: A method was developed to analyze the chemical constituents of pomegranate seeds, which led to the identification of 59 compounds. These findings provide a reference for the pharmacodynamic substance research of pomegranate seeds and reveal their potential nutritional and therapeutic applications in the future.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Evolutionary Biology
Wanyu Li, Chuang Zhou, Meiling Cheng, Hongmei Tu, Guannan Wang, Yeming Mao, Yaohua Huang, Minghua Chen, Megan Price, Yang Meng, Bisong Yue, Xiuyue Zhang
Summary: There are only six isolated living giant panda populations in China, and a comprehensive understanding of their genetic health status is crucial for their conservation. This study focused on the Liangshan Mountains, one of the main distribution areas of giant pandas, and found moderate genetic diversity and potential risks of inbreeding and genetic decline in the three reserves studied. Urgent human management is needed to protect these populations and ensure their survival.
EVOLUTIONARY APPLICATIONS
(2023)
Article
Engineering, Electrical & Electronic
Qi Wang, Chenhui Lin, Wenchuan Wu, Bin Wang, Guannan Wang, Haitao Liu, Hongyu Zhang, Jun Zhang
Summary: This paper proposes a nested decomposition method for multilevel AC optimal power flow problem, which computes the optimal objective value of a lower level power grid projected onto its boundary variable space during each iteration. The method has superlinear convergence and high efficiency, suitable for nonlinear continuous optimization problems.
IEEE TRANSACTIONS ON POWER SYSTEMS
(2023)
Article
Oncology
Xinwen Kuang, Zixuan Luo, Zhihong Sun, Jiawei Hu, Jianhua Liu, Deguang Kong, Guannan Wang, Liantao Guo, Lan Luo, Weijie Zheng, Shengrong Sun, Yan Rao, Chuang Chen
Summary: This article investigates the invasion transition mechanism of ER-positive breast cancer (BC) and triple-negative breast cancer (TNBC) using carbon nanoparticles (CNPs) as a tracer. The results show distinct invasion patterns between the two subtypes, suggesting different mechanisms involved in the progression from ductal carcinoma in situ (DCIS) to invasive BC.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Biochemical Research Methods
Yuhan Shang, Xianshuang Meng, Juan Liu, Naining Song, Hongyan Zheng, Chao Han, Qiang Ma
Summary: Mass spectrometry (MS) is widely utilized in cosmetic analysis for various purposes including ingredient screening, quality control, risk monitoring, authenticity verification, and efficacy evaluation. This article provides an overview of the role of MS in cosmetic analysis over the past two decades, highlighting the sample preparation methods, ionization techniques, and mass analyzer types commonly employed in this field. Additionally, the article briefly discusses the future development of MS for cosmetic analysis.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Biochemical Research Methods
Ming Li, Chenrui Zhan, Yueguang Lv, Jiwen Chen, Yutian Wang, Sixian Lu, Yingqi Wan, Qiang Ma
Summary: This study investigates the processing effects of ensemble empirical mode decomposition (EEMD) feature enhancement methods on the determination coefficient (R-2) and relative standard deviation (RSD) of caffeine mass spectrometry signals. The results show that the EEMD method is better than the wavelet analysis method and significantly improves the determination coefficient and RSD of the sample curve, improving the accuracy and stability of the data.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Biochemical Research Methods
Xiangyu Guo, Junfang Li, Hua Bai, Qiang Ma
Summary: In this study, a rapid on-site analytical workflow was developed for the detection of polycyclic aromatic hydrocarbons and perfluorinated compounds using multiwalled carbon nanotube-modified paper spray ionization coupled with a miniature ion trap mass spectrometer. Critical parameters regarding PSI and miniature mass spectrometry analysis were optimized. The developed method showed a short analysis duration, sufficient linearity, acceptable recovery rates, and reasonable sensitivity, making it a promising solution for the rapid on-site detection of emerging persistent organic pollutants.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Chemistry, Physical
Qiang Ma, Sha Fu, An-Jun Wu, Qi Deng, Wei-Dong Li, Dan Yue, Bing Zhang, Xiong-Wei Wu, Zhen-Ling Wang, Yu-Guo Guo
Summary: Bidirectionally functional polymer electrolytes (BDFPE) were designed to simultaneously handle the interface issues faced by anodes and cathodes. By constructing the BDFPE, a smooth and dendrite-free lithium deposition is enabled for Li||Li symmetry cells, and Li||LiNi0.6Co0.2Mn0.2O2 batteries demonstrate favorable cycling and rate capability with a stable CEI layer. The study provides a promising design strategy for high energy density lithium metal batteries.
ADVANCED ENERGY MATERIALS
(2023)
Article
Food Science & Technology
Yuye Zhong, Tao Zhang, Wenshuo Zhang, Guannan Wang, Zhenhong Zhang, Pingping Zhao, Xinghai Liu, Houbin Li
Summary: To overcome the limitations of pure gelatin film, researchers successfully grafted quaternary ammonium groups onto a novel castor oil-based waterborne polyurethane to create composite films. The mechanical properties, thermal stability, water permeability, and oxygen permeability of these films improved significantly with the increase in waterborne polyurethane concentration. The composite films also demonstrated strong antibacterial properties against Escherichia coli and Staphylococcus aureus, and extended the shelf life of strawberries to more than 6 days. Therefore, this new composite material has the potential to serve as an alternative food packaging material.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Biochemical Research Methods
Tiantian Zhang, Xiwen Ye, Xin Luo, Zengyuan Niu, Huiyong Wang, Qiang Ma
Summary: The study developed a solvent-free pyrolysis gas chromatography-mass spectrometry method to screen for multiple restricted additives in polymer materials. The method successfully screened 33 restricted substances simultaneously, and verified the sensitivity, linear range, and recovery of the method. It also validated the method using various reference materials and applied it to analyze plastic products and recycled plastic samples. The method provided a comprehensive and thorough inspection without sample pretreatment, offering numerous advantages over traditional methods.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zhijin Yang, Binbin Lin, Xuliang Huang, Bing Shi, Qiang Ma, Chao Han, Yan Shen
Summary: This study uses GC-APCI-MS/MS to detect and identify 8 herbicide residues in plant-based foodstuffs. APCI, as a soft ionization technique, enhances sensitivity and selectivity by generating more molecular ions and/or protonated molecules. The method has a range of 0.5 to 50 ng/mL for calibration curves, with recoveries in the range of 76.3-108.5%. The limit of quantification for all samples is 1.0 μg/kg. The results demonstrate the potential of GC-APCI-MS/MS in routine detection and identification of herbicide residues in plant-based foodstuffs.
MICROCHEMICAL JOURNAL
(2023)
Article
Polymer Science
Xuya Fu, Tao Zhang, Wenshuo Zhang, Yuye Zhong, Shuliang Fang, Guannan Wang, Ying Li, Yajun Deng, Xinghai Liu, Houbin Li
Summary: Curcumin was incorporated into castor oil-based polyurethane (CCPU) as a chain extender and melt with polylactic acid (PLA) to obtain a biomass UV-shielding film. The film showed impressive UV-shielding capacity (97.6% UV radiation absorption) and antioxidant activity (51% free radical scavenging) due to the excellent UV absorption and antioxidant qualities of curcumin. The addition of CCPU to the PLA matrix enhanced the toughening fracture characteristics and maintained the thermal stability, low water swelling degree, and low water solubility of the blend films. Therefore, the PLA/CCPU blend films are considered as potential packaging materials with favorable UV-shielding properties and film stability.
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).