Article
Multidisciplinary Sciences
Rakan B. AlRashidi, Othman Charles S. Al Hamouz
Summary: The study synthesized and characterized two new pyrazine-based polymers for the removal of mercury(II) ions from wastewater solutions. The results showed that the MXR-1 polymer exhibited a higher adsorption capacity and removal efficiency compared to the MXR-2 polymer, making it a potential adsorbent for wastewater purification.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2022)
Article
Energy & Fuels
Jianping Yang, Qin Li, Wenbing Zhu, Wenqi Qu, Min Li, Zhengyong Xu, Zequn Yang, Hui Liu, Hailong Li
Summary: This study utilized the abundant mineral chalcopyrite as an efficient trap for Hg-0 sequestration, showing excellent removal performance in a wide temperature range and minimal interference from typical flue gas components. The adsorption capacity and rate of CuFeS2 were significantly higher than commercial activated carbons, attributed to the oxidizing and immobilizing abilities of disulfide ligands, and the sorbent could be regenerated through thermal decomposition, saving operation costs. CuFeS2 is identified as a potential, cost-effective trap for efficient remediation of Hg-0 from coal combustion flue gas.
Article
Engineering, Environmental
Tingting Ren, Hanmeng Yuan, Junwen Peng, Zhihuan Liu, Guanhua Yang, Jianzheng Qiao, Xin Guo, Yiqiang Wu
Summary: In this study, a facile method was used to fabricate a nontoxic fluorescent wood (NFW) with a reconstructed porous structure and increased sorption sites for the selective detection and efficient removal of divalent mercury (Hg(II)). The NFW exhibited strong adsorption ability, excellent sensitivity for Hg(II) detection, and no cytotoxicity, making it a low-cost, multifunctional, and nontoxic adsorbent.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Engineering, Environmental
Yingchao Cheng, Yuki Asaoka, Yoshiyuki Hachiya, Naoki Moriuchi, Kenji Shiota, Kazuyuki Oshita, Masaki Takaoka
Summary: The study found that elemental mercury was the dominant species in a sewage sludge torrefaction plant. Total suspended solid removal from wastewater is recommended to reduce mercury discharge. Existing air pollution control devices may not be effective in removing mercury and further removal units may be necessary.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Isabella Nicotera, Alfonso Policicchio, Giuseppe Conte, Raffaele Giuseppe Agostino, Ernestino Lufrano, Cataldo Simari
Summary: A novel polymeric sorbent has been synthesized by modifying polysulfone with quaternary ammonium groups. It exhibits high CO2 adsorption capacity, good stability, and fast capture kinetics, making it suitable for low-temperature and low-pressure CO2 sorption.
JOURNAL OF CO2 UTILIZATION
(2022)
Article
Green & Sustainable Science & Technology
Chao Xiong, Can Xue, Liyun Huang, Peng Hu, Ping Fan, Shixing Wang, Xiantai Zhou, Zujin Yang, Yongqing Wang, Hongbing Ji
Summary: The study developed a novel bio-sorbent, PP-DBD, by functionalizing pomelo peels to efficiently remove Pb(II) from water with good selectivity, reusability, and high adsorption capacity. PP-DBD was found to have multiple active sites, chemisorption behavior, and positive synergism in surface diffusion. Thermodynamic analysis indicated enhanced adsorption of Pb(II) at higher temperatures, and DFT and FMOs calculations showed that hydroxyl sites on PP-DBD had better affinity and easier charge transfer capacity to Pb(II) than amino sites.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Isabella Nicotera, Alfonso Policicchio, Giuseppe Conte, Raffaele Giuseppe Agostino, Muhammad Habib Ur Rehman, Ernestino Lufrano, Cataldo Simari
Summary: In this study, a polymeric membrane functionalized with trimethylammonium groups was synthesized and evaluated as a CO2 sorbent. The membrane exhibited satisfactory performance in terms of stability, rapid adsorption, high selectivity, and working capacity. The quaternary ammonium groups enable superior amine efficiency and reversible trap-release of CO2. The low cost, versatility, and ease of preparation make this membrane a promising candidate for scalable and cost-effective CO2 capture.
JOURNAL OF CO2 UTILIZATION
(2022)
Article
Materials Science, Multidisciplinary
Q. A. Alsulami, M. A. Hussein, S. Z. Alsheheri, E. A. Elshehy, W. A. El-Said
Summary: This study focuses on the industrial application of silica/thiourea-formaldehyde composite monoliths for recovering silver and mercury ions from contaminated samples. The fabricated composite shows unique surface properties and high adsorption capacities for the target ions. The findings demonstrate the potential of the designed composite for efficient and reproducible adsorption of silver and mercury ions in environmental and waste disposal samples.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Energy & Fuels
Jiexia Zhao, Hailong Li, Zequn Yang, Wenqi Qu, Jianping Yang, Zhengyong Xu, Hui Liu, Kaimin Shih
Summary: The study found that light irradiation significantly inhibited the removal efficiency of CuS sorbent for Hg-0, mainly by hindering the formation of copper amalgam and accelerating the decomposition of copper amalgam into Hg-0.
Article
Chemistry, Multidisciplinary
Claudine El Khoueiry, Fabrice Giusti, Evan Lelong, Guilhem Arrachart, Bilal Nsouli, Iyad Karame, Stephane Pellet-Rostaing
Summary: This study found that thiourea formo-phenolic polymers as adsorbents have good affinity and high adsorption capacity for mercury (Hg) removal, with the potential for regeneration after desorption, highlighting their potential in the remediation of mercury-contaminated water.
Article
Engineering, Chemical
Xiaopeng Zhang, Yuying Wei, Lianhao Zhang, Xinxin Wang, Ning Zhang, Junjiang Bao, Gaohong He
Summary: Adsorption is an effective method for removing Hg0 from flue gas, and the morphology and active site of sorbents play a crucial role in the removal efficiency. By utilizing a hierarchical porous nanosheet-based nanotube structure, the mass transfer resistance can be reduced and more active sites can be provided. Organic-inorganic hybrid nanowires of Co-aspartic acid were used as a template to prepare CuCo2O4 sorbents with favorable physicochemical properties. The CuCo2O4-1-2 sorbent exhibited the best hierarchical porous nanosheet-based nanotube structure, excellent redox properties, high Hg0 removal efficiency of 89%, good poisoning resistance, and stability under specific conditions. The Cu-Co active site on the CuCo2O4 surface played a crucial role in capturing and activating O2.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Environmental
Jing Li, Guo Lin, Biao Zeng, Likang Fu, Zeying Wang, Shixing Wang, Tu Hu, Libo Zhang
Summary: In this study, titanium-metal organic framework (Ti-MOF) was synthesized and further modified for adsorbing toxic mercury ions in wastewater. The resulting material, OB-MIL-125(Ti), showed a high specific surface area and excellent adsorption capacity for mercury. It has great potential for remediation of mercury-containing wastewater.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2023)
Article
Environmental Sciences
Yuting Hu, Shixing Wang, Libo Zhang, Fan Yang
Summary: In this study, a novel MOF adsorbent (UiO-66-QU) was prepared and characterized, and its Hg(II) adsorption performance was investigated. The results showed that UiO-66-QU has better Hg(II) adsorption capacity than UiO-66-NH2, and the adsorption process is mainly monolayer chemical adsorption. The adsorbent exhibits excellent reusability and selectivity, making it promising for the removal of Hg(II) from wastewater.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Spectroscopy
Min Chen, Jun Wang, Qianbo Zhang, Jinsheng Zhang, Zhiming Chen, Rongguo Sun
Summary: In this study, N, S co-doped carbon nanodots (NS-CDs) were used for fluorescent monitoring of Hg2+ with high sensitivity. Thymine modification further enhanced the sensitivity and the sensing system was also applicable for Hg2+ detection in tap water.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Applied
Hossein Moradi Aliabadi, Kiomars Zargoosh
Summary: A highly selective adsorbent for Hg2+ ions, ATT@PDA-COP, was synthesized by functionalizing p-phenylenediamine (p-PDA) based covalent organic polymer with 3-amino-1,2,4 triazole,5-thiol (ATT). The adsorbent showed successful selective adsorption of Hg2+ ions in the presence of Cd2+ and Pb2+ ions. Characterization techniques including FT-IR, PXRD, FE-SEM, EDX, CHNS elemental analysis, and BET analysis confirmed the successful grafting of ATT onto PDA-COP. The adsorption characteristics of ATT@PDA-COP were evaluated, and the Langmuir isotherm model provided the best fit, with a maximum adsorption capacity of 312.5 mg g-1.
REACTIVE & FUNCTIONAL POLYMERS
(2023)
Article
Spectroscopy
Lingling Zhang, Mengwen Yi, Shilong Zhong, Jing Liu, Xiangjun Liu, Tao Bing, Nan Zhang, Yongbiao Wei, Dihua Shangguan
Summary: The viscosity of the cell microenvironment is crucial for maintaining normal cellular activities, with abnormal viscosity in mitochondria linked to various diseases. Novel p-aminostyryl thiazole orange derivatives have been developed, showing good fluorescence response to viscosity and potential for monitoring mitochondrial viscosity changes and investigating physiological processes related to inflammation and lipid metabolism.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Medicine, Research & Experimental
Nan Zhang, Junyan Wang, Tao Bing, Xiangjun Liu, Dihua Shangguan
Summary: Aptamers have high specificity and affinity in targeting cell surface receptors, making them promising for targeted drug delivery. Understanding the receptor-mediated internalization process of aptameric conjugates can aid in designing new targeted drugs. In this study, human transferrin receptor-targeted DNA aptamer-fluorophore conjugates were used to study the internalization, intracellular transport, and environmental pH of aptameric conjugates. The results showed that the aptameric conjugates had lower recycling ratios and dissociated from receptors, suggesting they could efficiently release loaded drugs and serve as a versatile tool for specific and effective delivery of therapeutic payloads.
MOLECULAR THERAPY-NUCLEIC ACIDS
(2022)
Article
Chemistry, Analytical
Yue Sun, Zhicheng Zhang, Tao Bing, Jing Liu, Weiwei Li, Xiangjun Liu, Nan Zhang, Yang Shu, Jianhua Wang, Dihua Shangguan
Summary: Aptamer-based Expansion Microscopy (ExM) is a newly developed imaging technology that allows nanoscale imaging under conventional microscopes. This technique utilizes chemically labeled aptamers for molecular recognition, fluorescence reporting, and gel anchoring, enabling high-resolution imaging after gel expansion. It offers a simple and promising approach for super-resolution imaging of cells and tissues.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Tianjun Chang, Guangping Li, Zhan Ding, Weiguo Li, Panpan Zhu, Wei Lei, Dihua Shangguan
Summary: This study discovered a prevalence of putative G4-forming sequences (PQSs) in nuclease hypersensitive sites within the promoters of heat-responsive genes in rice. The study also demonstrated that these PQSs could adopt stable G4 structures at physiological temperature and exhibit structural switch in response to temperature changes.
Article
Chemistry, Analytical
Jing Lv, Xiaoxiao Zhen, Dandan Li, Guomiao Liao, Zhenhao Long, Nan Zhang, Xiangjun Liu, Tao Bing, Dihua Shangguan
Summary: Cell-SELEX is a powerful tool for generating aptamers that specifically bind to native molecules on living cells. In this study, an aptamer named ZAJ4a was generated using cell-SELEX and was shown to have high binding affinity to cancer cells expressing the receptor-type tyrosine-protein phosphatase F (PTPRF). This aptamer can potentially be used as a molecular probe to identify biomarkers on the cell surface.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Zhenhao Long, Tao Bing, Xiangru Zhang, Jing Sheng, Shuang Zu, Weiwei Li, Xiangjun Liu, Nan Zhang, Dihua Shangguan
Summary: The L1 cell adhesion molecule (L1CAM) plays important roles in the development and plasticity of the nervous system as well as in tumor formation, progression, and metastasis. DNA aptamers yly20 and yly21, optimized through sequence mutation and extension, exhibit much stronger binding affinity to L1CAM at both room temperature and 37 degrees C. These aptamers adopt a hairpin structure containing two loops and two stems, with key nucleotides for binding mainly located in loop I and its adjacent area. This study provides insights into the molecular mechanism of the interaction between yly-series aptamers and L1CAM, and has implications for drug development and detection probe design against L1CAM.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Jing Liu, Xiangjun Liu, Mengwen Yi, Yue Sun, Tao Bing, Nan Zhang, Dihua Shangguan
Summary: A photo-activated aptamer-drug conjugate, HG1-9-DNP, was developed, which could release a cytotoxic agent DNNH upon photocleavage, resulting in high photo-induced cytotoxicity.
CHEMICAL COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Jing Lv, Shengnan Li, Xiaoxiao Zhen, Dandan Li, Nan Zhang, Xiangjun Liu, Juanjuan Han, Tao Bing, Dihua Shangguan
Summary: In this study, stable and environmentally sensitive aptamers were optimized from an original cell-binding aptamer. These aptamers selectively captured and released CD49c positive cells, providing a toolbox for studying the heterogeneity of rare cells.
ACS APPLIED BIO MATERIALS
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).