Dendritic cell targeted vaccines: Recent progresses and challenges

TLR3-Mediated CD8+Dendritic Cell Activation Is Coupled with Establishment of a Cell-Intrinsic Antiviral State

(2015) Lajos Széles et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis vaccines – rethinking the current paradigm

(2014) Peter Andersen et al.   TRENDS IN IMMUNOLOGY

B-lymphocyte tolerance and effector function in immunity and autoimmunity

(2013) Wasif N. Khan et al.   IMMUNOLOGIC RESEARCH

Protective immunity against malaria after vaccination

(2013) J. B. de Souza   PARASITE IMMUNOLOGY

The physiological role of DC-SIGN: A tale of mice and men

(2013) Juan J. Garcia-Vallejo et al.   TRENDS IN IMMUNOLOGY

Vaccine delivery using nanoparticles

(2013) Anthony E. Gregory et al.   Frontiers in Cellular and Infection Microbiology

Comparison of antibodies and carbohydrates to target vaccines to human dendritic cells via DC-SIGN

(2012) Luis J. Cruz et al.   BIOMATERIALS

The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells

(2012) G. Schreibelt et al.   BLOOD

Fc  receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

(2012) T. W. H. Flinsenberg et al.   BLOOD

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

(2012) Wendy W.J. Unger et al.   JOURNAL OF CONTROLLED RELEASE

Skin Langerin+ Dendritic Cells Transport Intradermally Injected Anti-DEC-205 Antibodies but Are Not Essential for Subsequent Cytotoxic CD8+ T Cell Responses

(2012) V. Flacher et al.   JOURNAL OF IMMUNOLOGY

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells

(2012) Juan J. García-Vallejo et al.   MOLECULAR IMMUNOLOGY

CD205 antigen targeting combined with dendritic cell recruitment factors and antigen-linked CD40L activation primes and expands significant antigen-specific antibody and CD4+ T cell responses following DNA vaccination of outbred animals

(2012) Leo M. Njongmeta et al.   VACCINE

Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting

(2011) Jean-Sébastien Thomann et al.   BIOMATERIALS

Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity

(2011) P. J. Tacken et al.   BLOOD

Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine

(2011) B. N. Hangalapura et al.   CANCER RESEARCH

Lewis X oligosaccharides–heparanase complex targeting to DCs enhance antitumor response in mice

(2011) Hongjie Chen et al.   CELLULAR IMMUNOLOGY

Route of Administration Modulates the Induction of Dendritic Cell Vaccine-Induced Antigen-Specific T Cells in Advanced Melanoma Patients

(2011) W. J. Lesterhuis et al.   CLINICAL CANCER RESEARCH

Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization

(2011) Satwinder Kaur Singh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

(2011) Kathrin Kastenmüller et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

(2011) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

(2011) Irina Caminschi et al.   MOLECULAR IMMUNOLOGY

Activation of Antigen-Specific T Cell-Responses by Mannan-Decorated PLGA Nanoparticles

(2011) Samar Hamdy et al.   PHARMACEUTICAL RESEARCH

Dendritic Cell Based Tumor Vaccination in Prostate and Renal Cell Cancer: A Systematic Review and Meta-Analysis

(2011) Andreas Draube et al.   PLoS One

Targeting human dendritic cell subsets for improved vaccines

(2011) Hideki Ueno et al.   SEMINARS IN IMMUNOLOGY

Boosting antibody responses by targeting antigens to dendritic cells

(2011) Irina Caminschi et al.   TRENDS IN IMMUNOLOGY

Harnessing human dendritic cell subsets for medicine

(2010) Hideki Ueno et al.   IMMUNOLOGICAL REVIEWS

Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro

(2010) Luis J. Cruz et al.   JOURNAL OF CONTROLLED RELEASE

Targeting Nanosystems to Human DCs via Fc Receptor as an Effective Strategy to Deliver Antigen for Immunotherapy

(2010) Luis J. Cruz et al.   MOLECULAR PHARMACEUTICS

Harnessing Dendritic Cells to Generate Cancer Vaccines

(2009) Karolina Palucka et al.   Annals of the New York Academy of Sciences

Improving vaccines by targeting antigens to dendritic cells

(2009) Ken Shortman et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation

(2009) Satwinder Kaur Singh et al.   MOLECULAR IMMUNOLOGY

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Innate signaling by the C-type lectin DC-SIGN dictates immune responses

(2008) Jeroen den Dunnen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses

(2008) Fernanda V. V. Castro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Circumvention of regulatory CD4+ T cell activity during cross-priming strongly enhances T cell-mediated immunity

(2008) Antje Heit et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Engineered lentivector targeting of dendritic cells for in vivo immunization

(2008) Lili Yang et al.   NATURE BIOTECHNOLOGY