Review of Synthesis of Spiro Heterocyclic Compounds from Isatin

[Hmim][HSO4]: An Efficient and Reusable Catalyst for the Synthesis of Spiro[dibenzo[a,i]-xanthene-14,3'-indoline]-2',8,13-triones and Spironaphthopyran[2,3-d]pyrimidine-5,3'-indolines

(2012) Xiaojuan Yang et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Synthesis of Spiro Heterocyclic Compounds

(2012) Mohamed N. Ibrahim et al.   E-Journal of Chemistry

Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity

(2012) Gangaru Bhaskar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Zeolite supported Brønsted-acid ionic liquids: an eco approach for synthesis of spiro[indole-pyrido[3,2-e]thiazine] in water under ultrasonication

(2012) Kapil Arya et al.   GREEN CHEMISTRY

Brønsted acidic ionic liquids: Green, efficient and reusable catalyst for synthesis of fluorinated spiro [indole-thiazinones/thiazolidinones] as antihistamic agents

(2012) Kapil Arya et al.   JOURNAL OF FLUORINE CHEMISTRY

Diastereo- and Enantioselective [3 + 2] Cycloaddition Reaction of Morita–Baylis–Hillman Carbonates of Isatins with N-Phenylmaleimide Catalyzed by Me-DuPhos

(2012) Yan Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of the functionalized spiro[indoline-3,5′-pyrroline]-2,2′-diones via three-component reactions of arylamines, acetylenedicarboxylates, and isatins

(2012) Ying Han et al.   TETRAHEDRON

A one-pot, three-component synthesis of spiro[indoline-isoxazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidine]triones in water

(2012) Abbas Rahmati et al.   TETRAHEDRON

Use of SO3H-functionalized halogenfree ionic liquid ([MIM(CH2)4SO3H] [HSO4]) as efficient promoter for the synthesis of structurally diverse spiroheterocycles

(2012) Mahendra Kumar et al.   TETRAHEDRON LETTERS

Building libraries of skeletally diverse scaffolds from novel heterocyclic active methylene compound through multi-component reactions

(2012) Ramasamy Jayarajan et al.   TETRAHEDRON LETTERS

New multicomponent domino reaction on water: highly diastereoselective synthesis of spiro[indoline-3,4′-pyrazolo[3,4-b]pyridines] catalyzed by NaCl

(2012) Anshu Dandia et al.   TETRAHEDRON LETTERS

One-pot efficient green synthesis of spirooxindole-annulated thiopyran derivatives via Knoevenagel condensation followed by Michael addition

(2012) K.C. Majumdar et al.   TETRAHEDRON LETTERS

Rh2(OAc)4 catalyzed substrate selective [4+2]/[2+2] cycloaddition of acylketenes: a highly chemo- and regioselective synthesis of spiro(oxindolyl)oxazinones and β-lactams

(2012) B.V. Subba Reddy et al.   TETRAHEDRON LETTERS

A greener, facile and scalable synthesis of indole derivatives in water: reactions of indole-2,3-diones with 1,2-difunctionalized benzene

(2012) Renuka Jain et al.   TETRAHEDRON LETTERS

A facile synthesis of novel ferrocene grafted spiro-indenoquinoxaline pyrrolizidines via one-pot multicomponent [3+2] cycloaddition of azomethine ylides

(2012) A.R. Suresh Babu et al.   TETRAHEDRON LETTERS

Synthesis of 1′-aryl-2′-(2-oxoindolin-3-yl)spiro[indoline-3,5′-pyrroline]-2,3′-dione via one-pot reaction of arylamines, acetone, and isatins

(2012) Yan Sun et al.   TETRAHEDRON LETTERS

A novel one-pot synthesis of spiro[indoline-3,4′-pyrazolo[3,4-e][1,4]thiazepine] diones using recyclable bioglycerol-based sulfonic acid functionalized carbon catalyst

(2012) K. Karnakar et al.   TETRAHEDRON LETTERS

An efficient strategy for functionalized spirolactones and dispirodihydrofuranyl oxindoles using amines and activated alkynes

(2012) Selvarangam E. Kiruthika et al.   TETRAHEDRON LETTERS

One-Pot, Three-Component Synthesis of a Library of Spirooxindole-Pyrimidines Catalyzed by Magnetic Nanoparticle Supported Dodecyl Benzenesulfonic Acid in Aqueous Media

(2012) Jia Deng et al.   ACS Combinatorial Science

Synthesis and QSAR study of novel cytotoxic spiro[3H-indole-3,2′(1′H)-pyrrolo[3,4-c]pyrrole]-2,3′,5′(1H,2′aH,4′H)-triones

(2011) Adel S. Girgis et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Spiro[pyrrolidine-2,3′-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions

(2011) Gang Chen et al.   MOLECULAR DIVERSITY

Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction

(2011) Yong-Mei Xie et al.   MOLECULES

A regioselective and diastereoselective synthesis of new spiro-isoxazolidines via 1,3-dipolar cycloaddition of stable isatin ketonitrone and various dipolarophiles

(2011) Morteza Mehrdad et al.   MONATSHEFTE FUR CHEMIE

Synthesis of New Spiro[1,4,2-dioxazole-5,3′-indolin]-2′-one by 1,3-Dipolar Cycloaddition

(2011) Rachid Bouhfid et al.   SYNTHETIC COMMUNICATIONS

Facile Three-Component Synthesis of Spirooxindolepyrrololine Ring Systems via 1,3-Dipolar Cycloaddition with 1,4-Naphthoquinone

(2011) Hua Chen et al.   SYNTHETIC COMMUNICATIONS

Efficient one-pot synthesis of spiro[indoline-3,4′-pyrazolo[3,4-e][1,4]thiazepine]dione via three-component reaction

(2011) Hui Chen et al.   TETRAHEDRON

Ambient synthesis of spiro[4H-pyran-oxindole] derivatives under [BMIm]BF4 catalysis

(2011) Kurosh Rad-Moghadam et al.   TETRAHEDRON

Novel four-component route to the synthesis of spiro[indoline-3,4′-pyridine]-3′-carboxylate derivatives

(2011) Abdolali Alizadeh et al.   TETRAHEDRON

New four-component reactions in water: a convergent approach to the metal-free synthesis of spiro[indoline/acenaphthylene-3,4′-pyrazolo[3,4-b]pyridine derivatives

(2011) Kamaraj Balamurugan et al.   TETRAHEDRON

Unusual mechanistic pathway for the synthesis of novel spiro-oxindoles via 3-phenyl-5-isoxazolone ring cleavage by secondary amino acids

(2011) Neelakandan Vidhya Lakshmi et al.   TETRAHEDRON LETTERS

A facile strategy for the one pot multicomponent synthesis of spiro dihydropyridines from amines and activated alkynes

(2011) Selvarangam E. Kiruthika et al.   TETRAHEDRON LETTERS

Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio- and stereoselective 1,3-dipolar cycloaddition

(2011) Stephen Michael Rajesh et al.   MedChemComm

Rapid and Efficient Ultrasound-Assisted Method for the Combinatorial Synthesis of Spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] Derivatives

(2011) Yi Zou et al.   ACS Combinatorial Science

Organocatalytic synthesis of spiro compounds via a cascade Michael–Michael-aldol reaction

(2010) Xavier Companyó et al.   CHEMICAL COMMUNICATIONS

Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide

(2010) Arumugam Thangamani   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building

(2010) Tarek Aboul-Fadl et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Efficient One-Pot Synthesis of Novel Spirooxindole Derivatives via Three-Component Reaction in Aqueous Medium

(2010) Hui Chen et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Counter-Current chromatography separation of isatin derivatives using the sandmeyer methodology

(2010) Márcia R. Almeida et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

A facile synthesis of chromeno[3,4-c]spiropyrrolidine-oxindoles via 1,3-dipolar cycloadditions

(2010) Mehdi Ghandi et al.   TETRAHEDRON

An experimental and theoretical investigation of the regio- and stereoselectivity of the polar [3+2] cycloaddition of azomethine ylides to nitrostyrenes

(2010) Kamal Alimohammadi et al.   TETRAHEDRON

Ultrasound-promoted synthesis of novel spirooxindolo/spiroacenaphthen dicyano pyrrolidines and pyrrolizidines through regioselective azomethine ylide cycloaddition reaction

(2010) Seyed Jamal Tabatabaei Rezaei et al.   ULTRASONICS SONOCHEMISTRY

Efficient Synthesis of Spiro[chromeno[2,3-d]pyrimidine-5,3′-indoline]-tetraones by a One-Pot and Three-Component Reaction

(2009) Khosrow Jadidi et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Maya Blue as a nanostructured polyfunctional hybrid organic–inorganic material: the need to change paradigms

(2009) Antonio Doménech et al.   NEW JOURNAL OF CHEMISTRY

Synthesis of 1H-Indole-2,3-Dione-3-Thiosemicarbazone Ribonucleosides as Antibacterial Agents

(2009) Shaymaa E. Kassab et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

An expedient synthesis of ferrocene grafted spirooxindolopyrrolizidines via [3+2]-cycloaddition of azomethine ylides

(2009) A.R. Suresh Babu et al.   TETRAHEDRON

Spirooxindoles: reaction of 2,6-diaminopyrimidin-4(3H)-one and isatins

(2009) Khosrow Jadidi et al.   TETRAHEDRON

DBU-Catalyzed, facile and efficient method for synthesis of spirocyclic 2-oxindole derivatives with incorporated 6-amino-4H-pyridazines and fused derivatives via [3+3] atom combination

(2009) Ismail A. Abdelhamid et al.   TETRAHEDRON

Synthesis of spiro[benzopyrazolonaphthyridine-indoline]-diones and spiro[chromenopyrazolopyridine-indoline]-diones by one-pot, three-component methods in water

(2009) Somayeh Ahadi et al.   TETRAHEDRON

Synthesis of novel spiropyrrolidine/pyrrolizine-oxindole scaffolds through 1,3-dipolar cycloadditions

(2009) Mehdi Ghandi et al.   TETRAHEDRON LETTERS

Grindstone chemistry: one-pot synthesis of spiro[diindenopyridine-indoline]triones and spiro[acenaphthylene-diindenopyridine]triones

(2009) Ramin Ghahremanzadeh et al.   TETRAHEDRON LETTERS

Synthesis of ferrocenyl monospirooxindolopyrrolidines—a facile [3+2]-cycloaddition of azomethine ylides

(2008) A.R. Suresh Babu et al.   TETRAHEDRON LETTERS