4.3 Article

Room-Temperature Synthesis of Diindolylmethanes Using Silica-Supported Sulfuric Acid as a Reusable Catalyst Under Solvent-Free Conditions

期刊

SYNTHETIC COMMUNICATIONS
卷 41, 期 16, 页码 2446-2454

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2010.505696

关键词

Aldehydes; H2SO4 center dot SiO2; indole; solvent-free

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[image omitted] Efficient electrophilic substitution reactions of indoles with various aromatic and aliphatic aldehydes were carried out using a catalytic amount of H2SO4 center dot SiO2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.

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