Article
Chemistry, Multidisciplinary
Nitin Tandon, Shripad M. Patil, Runjhun Tandon, Pushpendra Kumar
Summary: Novel silica-coated ferrite nanoparticles supported with montmorillonite (K-10) were successfully prepared via a simple impregnation method and characterized using various analytical techniques. These nanoparticles exhibited good catalytic activity in acylation reactions and could be easily separated and reused through an external magnetic field.
Article
Chemistry, Organic
Zijian Zhong, Pan Xu, Aihua Zhou
Summary: This method utilizes electrochemical dehydrogenative cross-coupling to generate organophosphates and phosphoramidates, using inorganic iodide salts as redox catalysts and electrolytes without the need for oxidants or bases. It has good functional group tolerance, high yields, and a wide substrate scope, showing potential for practical synthesis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Xiancui Zhu, Jinqiang He, Yuanqing Yang, Shuangliu Zhou, Yun Wei, Shaowu Wang
Summary: In this study, a series of unusual tridentate beta-diketiminato rare-earth metal complexes were synthesized and found to exhibit high catalytic activity towards the alcoholysis of isothiocyanates and aminolysis of epoxides. These complexes displayed good reactivity and regioselectivity in reactions with alcohols and isothiocyanates, as well as epoxides and arylamines.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Francesca Valentini, Pierluca Galloni, Diana Brancadoro, Valeria Conte, Federica Sabuzi
Summary: This study proposes a sustainable solvent-free acetylation reaction method, in which the naturally occurring phenol is converted to the corresponding ester with the presence of 1% of VOSO4 as catalyst. The method is not only applicable for the synthesis of other esters, but also for acetylation of alcohols and thiols, and a greener alternative, isopropenyl acetate, has been introduced for further improvement.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Yasser B. Saddeek, A. El-Denglawey, H. Doweidar
Summary: Research on ternary Al2O3-P2O5-Bi2O3 glasses revealed that ultrasonic features are influenced by Al2O3, which tends to insert into the phosphate network to form (AlO4) units. This study correlated changes in density and ultrasonic velocities with structural variations represented by FTIR spectra to examine the function of Al2O3 in the glasses' network. The analysis also inferred variations in structure and elastic moduli based on oscillations of different structural units and the substitution of Bi2O3 with Al2O3.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2021)
Article
Chemistry, Multidisciplinary
Yu-Fang Tan, Dan Yang, Ya-Nan Zhao, Jin-Feng Lv, Zhi Guan, Yan-Hong He
Summary: An electrochemical method for the direct synthesis of 1,2-diester derivatives from olefins and carboxylic acids is described. The method is environmentally friendly, does not require metals, catalysts, or oxidants, and produces the desired products in moderate to good yields. The only by-product is hydrogen, making this method clean and efficient. The synthesis of diesters of drugs and natural products further demonstrates the applicability of the method.
Article
Chemistry, Multidisciplinary
Ashu Gupta, Indu Tucker Sidhwani, Radhika Gupta, Yukti Monga, Rakesh Kumar Sharma
Summary: In this paper, a sustainable pathway for the synthesis of acetanilide moieties was presented, utilizing sunlight and MgSO4 as a Lewis acid catalyst. The process exhibited utmost selectivity, shorter reaction time, and excellent yields.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Ashu Gupta, Indu Tucker Sidhwani, Radhika Gupta, Yukti Monga, Rakesh Kumar Sharma
Summary: In this study, we have presented a sustainable pathway for the synthesis of industrially significant acetanilide moieties in the presence of sunlight using MgSO4 as a Lewis acid catalyst with utmost selectivity in less reaction time and excellent yields.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Robin Fertig, Felix Leowsky-Kuenstler, Torsten Irrgang, Rhett Kempe
Summary: Introducing unknown compound classes is crucial for expanding the chemical space. The authors propose a rational design concept and synthesis of unknown classes of N-heterocyclic compounds. The discovery of reactions is a central topic in chemistry, and the ability to synthesize unexplored compound classes is particularly fascinating. N-Heterocyclic compounds are highly important due to their wide applications in life and material sciences. The authors introduce a sequential three-component reaction, classes of N-heterocyclic compounds, and the regenerative cyclisation synthesis concept.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Yanling Zheng, Yang Long, Huihua Gong, Jiaqi Xu, Chunchun Zhang, Haiyan Fu, Xueli Zheng, Hua Chen, Ruixiang Li
Summary: In this study, the divergent transformations of 1,3-diols with arylhydrazines were reported, which selectively synthesized pyrazoles and 2-pyrazolines via acceptorless dehydrogenative coupling reactions using Ru3(CO)12/NHC-phosphinephosphine catalytic systems. The reactions showed low catalyst loading, high selectivity, wide substrate scope, and good yields, with only water and hydrogen gas (H2) as the byproducts.
Article
Chemistry, Multidisciplinary
Vladimir A. Maslivetc, James J. La Clair, Alexander Kornienko
Summary: Stable isoindole products can be synthesized in one step with acceptable yields and high purity by introducing electron-withdrawing substituents.
Article
Chemistry, Multidisciplinary
Jiazheng Zhu, Chengjie Duan, Sen Ye, Qizhong Zhang, Kun Li, Guangke He, Xiang Liu, Zhiguo Zhang
Summary: Exploring synthetic methods and catalysts that are easy to handle, highly active, and low-cost for producing industrially important chemicals is a long-term goal in both science and industry. Herein, we present a general and facile Ni-catalyzed reductive amination of aldehydes/ketones methodology using hydrazine as both nitrogen and hydrogen sources, instead of the traditionally used hydrogen gas and ammonia. The mesostructured alumina-supported Ni catalyst with a relatively high ratio of Ni-0 and small-sized Ni nanoparticles plays a critical role in this transformation, resulting in 55 aldehydes/ketones successfully converting to their corresponding primary amines with 61-99% yields. This work outlines a low-cost yet robust catalytic methodology for the facile and general synthesis of primary amines for practical laboratory and industrial application.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Shripad M. Patil, Ajit P. Ingale, Ashok S. Pise, Rahul S. Bhondave
Summary: Novel silica-coated magnetic nanoparticles doped with cobalt (Co3O4) were successfully manufactured using the straightforward co-precipitation approach. Characterization of these nanoparticles was conducted using various techniques such as FE-SEM, EDS, WDX, PXRD, FT-IR, TGA, ICP-OES, and TEM. Interestingly, these nanocrystals exhibited outstanding catalytic performance for acylation processes of amines, phenols, alcohols, and thiols in solvent-free conditions, with high yields. Furthermore, these nanoparticles showed excellent recyclability, maintaining their catalytic activity after being recycled at least 12 times.
Article
Chemistry, Multidisciplinary
Jianwei Wei, Liang Zhao, Yu Zhang, Gang Han, Cheng He, Chong Wang, Chunying Duan
Summary: An enzyme grafting strategy was used to create a metal-organic capsule-docking artificial enzyme that bypasses the need for cofactor shuttling and regeneration. This semi-artificial enzyme efficiently converts various types of alcohols to amine products in aqueous/organic solutions and Escherichia coli, offering opportunities for sustainable and environmentally friendly biomanufacturing.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Organic
Sangay Moktan, Mahendra K. V. Rotta, Suvendu Halder, Priyanka Pradhan, Pavan K. Kancharla
Summary: A simple and useful method for the synthesis of ethers and thioethers via Bronsted acid-catalyzed activation of ortho-[1-(p-MeOphenyl)vinyl]benzoate (PMPVB) donors derived from alcohols is reported. The mechanism involves the remote activation of an active alkene, followed by intramolecular 5-exo-trig cyclization to form a reactive intermediate that can react with alcohols and thiol nucleophiles via a substrate dependent S(N)1 or S(N)2 mechanism, providing easy access to ether and thioether functionalities, respectively.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Dilek Isik Tasgin, Irem Bayraktar
Summary: We present a synthetic method for pyrrolizine-3-one derivatives and investigate their photophysical properties. These compounds are prepared through a series of reactions involving substituted pyrroles in one-pot, two-step oxidation, and intramolecular cyclization processes. The photophysical properties of the synthesized compounds are studied using UV-Vis and fluorescence spectroscopy in various solvents. The introduction of pyrrolyl substituents has a significant impact on Stokes shifts and quantum yield values.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
Satish Kumar Burra, Vaikunta Rao Lakinani, Raghunadh Akula, Chiranjeevi Yankkanti
Summary: A novel and green strategy for the construction of biologically relevant substituted indolyl-4H-chromenes scaffolds is reported, using L-proline as a catalyst and water as a promoter solvent. This catalytic system offers wider applicability, shorter reaction times, and high yields, making it an ideal condition for green chemistry.
SYNTHETIC COMMUNICATIONS
(2024)
Review
Chemistry, Organic
Abouelhaoul El Alami, Amine El Maraghi, Fatima Youssoufi, Assiya Atif, Hamid Sdassi
Summary: Nitrobenzimidazoles have become increasingly important in the design of new compounds in medicinal, therapeutic and chemical fields. This review provides an overview of the synthesis strategies and biological activities of nitrobenzimidazole derivatives.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
Nilesh Raghunath Khedkar, Alex Joseph, Milind Sindkhedkar
Summary: In this study, a new library of 3-(2-(pyrimidin-5-yl)thiazol-4-yl)-1,2,4-oxadiazole compounds was designed and synthesized as potential anticancer agents using in silico fragment-based drug design. The compounds were tested for their anticancer activity in vitro, and one compound exhibited excellent activity against multiple cancer cell lines.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
Terungwa H. Iorkula, Bryce A. Tolman, Scott R. Burt, Matt A. Peterson
Summary: A new method for synthesizing C-6 substituted products has been discovered in this study, which utilizes lower doses of fluoride and CsF as a catalyst, with high reaction yields and cost-effectiveness under suitable conditions.
SYNTHETIC COMMUNICATIONS
(2024)
Review
Chemistry, Organic
Ranjana Aggarwal, Swati Sharma
Summary: This review article mainly focuses on the synthesis of 3(5)-trifluoromethylpyrazoles via condensation reaction of trifluoromethyl-beta-diketones with hydrazines. It emphasizes the importance of fluorine-containing compounds and pyrazoles in the field of biology. The literature reported condensation reactions of trifluoromethyl-beta-diketones with hydrazines are covered.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
F. M. Alshareef, Sami A. Al-Harbi, Esam S. Allehyani, Omeima Abdullah, Magdy A. Ibrahim
Summary: This study aimed to construct a novel category of linear annulated chromeno[3',2':5,6]pyrido[2,3-d][1,3]thiazolo[3,2-a]pyrimidines. The chemical reactivity of the synthesized compounds was investigated, and they showed significant antimicrobial activity against various strains.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Chemistry, Organic
Preethi Dhanapal, S. L. Manju
Summary: Thiazole based Schiff base scaffolds have become an integral part of drug development in recent years, playing a versatile role as building blocks for lead drug molecules. This study presents a facile one pot synthetic method for producing novel 4-aryl thiazoles with high yield, shorter reaction time, and milder conditions, without the need for catalysts or purification techniques.
SYNTHETIC COMMUNICATIONS
(2024)