4.5 Article

An Efficient Route to Difluoromethylated Pyridines

期刊

SYNTHESIS-STUTTGART
卷 44, 期 19, 页码 3015-3018

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1316761

关键词

fluorine; pyridines; copper; catalysis; cross-coupling; decarboxylations

资金

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan [22350043, 22106531]
  2. Asahi Glass Foundation
  3. Sumitomo Foundation
  4. Nagase Science and Technology Foundation
  5. Shorai Foundation for Science and Technology
  6. 'Element Innovation' Project by the Ministry of Education, Culture, Sports, Science, and Technology of Japan
  7. Grants-in-Aid for Scientific Research [22106531, 22350043, 24655073] Funding Source: KAKEN

向作者/读者索取更多资源

A convenient route to difluoromethylated pyridines was developed that involves copper-promoted cross-coupling of halopyridines with ethyl difluoro(trimethylsilyl)acetate and subsequent decarboxylation.

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