Review
Chemistry, Organic
Yuri Katayama, Harunobu Mitsunuma, Motomu Kanai
Summary: Organochromium(III) species are versatile nucleophiles used in complex molecule synthesis due to their high tolerance of functional groups and chemoselectivity for aldehydes. Traditional methods of carbonyl addition reactions using organochromium(III) species require stoichiometric chromium(II) salts or catalytic chromium salts and stoichiometric reductants. Recent alternative methods involve organoradical formation from readily available starting materials and trapping the radical with stoichiometric or catalytic chromium(II) salts. These methods have the potential to develop sustainable chemical processes.
SYNTHESIS-STUTTGART
(2022)
Review
Chemistry, Organic
Konstantinos A. A. Ouzounthanasis, Stergios R. R. Rizos, Alexandros E. E. Koumbis
Summary: The Julia-Kocienski olefination, a coupling reaction between a carbonyl component and a sulfone partner, has become an important tool in the synthetic toolbox for preparing various organic compounds. Recent studies have focused on the synthesis of trisubstituted alkenes and understanding their stereoselectivity. This review provides a comprehensive overview of the progress and developments in the application of Julia-Kocienski olefination for the synthesis of trisubstituted alkenes, which are valuable precursors for natural products, analogs, and biologically important compounds. The review also discusses key methodologies, optimal conditions, stereoselectivities, and new modifications and approaches.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Michal Kopyt, Michal Tryniszewski, Michal Barbasiewicz, Piotr Kwiatkowski
Summary: Enantioselective Michael addition under high-pressure conditions is an efficient method to synthesize chiral cyclohexanes.
Article
Chemistry, Multidisciplinary
Shinichiro Fuse, Sena Kanda, Hisashi Masui
Summary: Valuable indole derivatives were synthesized via the sequential 1,2-addition/nucleophilic substitution of indolyl-3-carbaldehydes. Microflow technology was used to suppress undesired reactions caused by unstable intermediates, leading to higher yields and reproducibility. The study provides a rapid and efficient method for the synthesis of structurally diverse indole derivatives.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Physical
Amishwar Raysing Shelte, Rakesh Nana Khatal, Sanjay Pratihar
Summary: The relocalization of charge at interfaces between metals and metal oxides can have significant implications for catalytic reactions. In this study, the application of nanoscale interfaces comprising zinc oxide-nickel oxide-nickel (ZnO-NiO-Ni) for the oxidative cleavage of carbon-carbon (C-C) multiple bonds was investigated. The results showed that the heterostructure between ZnO-NiO-Ni and their synergistic cooperation played a crucial role in achieving the desired oxidation reaction.
APPLIED CATALYSIS A-GENERAL
(2023)
Article
Chemistry, Organic
Xinpeng Jiang, Zicong Zheng, Yan Gao, Deyou Lan, Wenhao Xu, Wang Zhang, Guofei Chen
Summary: This study reported a metal-free synthesis method for producing methylenecyclobutane containing tetrasubstituted alkenyl nitriles using a strain-release driven addition reaction of [1.1.1]propellane. The protocol could be scaled up to gram quantities and the resulting alkenyl nitriles were capable of undergoing various derivatization reactions, offering a wide range of possible transformation reactions.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Inorganic & Nuclear
Masnun Naher, Chuyi Su, Jeffrey R. Harmer, Craig M. Williams, Paul V. Bernhardt
Summary: The utility and scope of Cu-catalyzed halogen atom transfer chemistry have been exploited in a variety of fields. This study demonstrates the ability to modulate the reactivity of the Cu catalyst using electrochemistry, resulting in unprecedented rate acceleration in Cu-catalyzed bulk electrosynthesis.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Ravi Kumar, Parveen Rawal, Indrani Banerjee, Hari Pada Nayek, Puneet Gupta, Tarun K. Panda
Summary: This study reports the solvent-free and ambient temperature chemoselective hydroboration of aldehydes and ketones using platinum complexes. The corresponding boronate esters were obtained in high yield. The platinum complexes also proved to be effective catalysts in the reductive amination reaction, showing excellent functional group tolerance.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Weiyu Li, Lei Zhou
Summary: This research reports a visible-light-driven radical 1,3-selenosulfonylation of vinyldiazo compounds with selenosulfonates, yielding various gamma-seleno allylic sulfones. The reaction was carried out at room temperature in an open flask using ethyl acetate as the solvent without the need for any photocatalysts or additives. Synthetic applications of the resulting products were demonstrated through deselenization, reduction, bromination, and allylation.
Article
Chemistry, Applied
Taravat Khodaei, Jhamak Nourmohammadi, Azadeh Ghaee, Zohreh Khodaii
Summary: This study developed a novel antibacterial, self-healing hydrogel made from aldehyde-carrageenan. The hydrogel was synthesized by oxidizing carrageenan and adding dopamine and zinc ions. The hydrogel showed excellent properties, including rapid recovery, reduced weight loss, antibacterial effects against E. coli, and enhanced collagen secretion and cell attachment. The hybrid hydrogel has great potential for wound healing applications.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Zhi-Yuan Zhao, Ming Cui, Elisabeth Irran, Martin Oestreich
Summary: This study successfully achieved highly enantioselective silylation of 3-substituted 2H-azirines using a copper-catalyzed reaction with a silyl boronic ester as a latent silicon nucleophile. The resulting C-silylated, unprotected (N-H) aziridines were obtained in high yields and with excellent enantioselectivities, and they can be further converted into valuable compounds without significant loss of enantiomeric excess.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Inorganic & Nuclear
Han-Ying Liu, Mary F. Mahon, Michael S. Hill
Summary: The potassium diamidoalumanyl reacts with pinacolato boron esters and B(OMe) to produce potassium (alkoxy)borylaluminate derivatives. The reactivity of these derivatives with heteroallene molecules highlights the kinetic inaccessibility of their Al-B bonds.
INORGANIC CHEMISTRY
(2023)
Article
Spectroscopy
Qinghua Wu, Shengyuan Wang, Erhong Hao, Lijuan Jiao
Summary: Two beta-formylBODIPYs show strong daylight excitable fluorescence and highly selective responses to cyanide anion. Surprisingly, cyanide anion undergoes nucleophilic addition to the alpha-position of the BODIPY core instead of the expected formyl moiety, causing interruption of pi-conjugation and significant blue-shift of absorption maxima.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Yan Xu, Xinhua Zheng, Jifei Sun, Weiping Wang, Mingming Wang, Yuan Yuan, Mingyan Chuai, Na Chen, Hanlin Hu, Wei Chen
Summary: A nucleophilic interfacial layer (NIL) was developed to achieve a stable Zn anode for aqueous Zn batteries, resulting in improved performance and extended lifespan.
Article
Agronomy
Yanyan Li, Ruzhen Wang, Heyong Liu, Xue Feng, Bin Wang, Zhirui Wang, Jiangping Cai, Lijuan Yang, Yong Jiang
Summary: Mowing can counteract the synergistic effect of nitrogen and zinc addition on plant zinc uptake in nitrogen-fertilized grasslands. This finding suggests the necessity of zinc fertilization in grassland management.
