期刊
SYNTHESIS-STUTTGART
卷 -, 期 2, 页码 249-254出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217108
关键词
multicomponent reactions; amines; catalysis; zinc; organometallic reagents
A Mannich-like zinc-mediated three-component reaction of aromatic halides, amines, and paraformaldehyde is described. This procedure, which involves the in situ formation of arylzinc reagents, allows the straightforward synthesis of a range of functionalized tertiary benzylamines.
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