期刊
SYNTHESIS-STUTTGART
卷 -, 期 14, 页码 2283-2287出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1078451
关键词
amines; enzymes; enantiomeric resolution; kinetic resolution
Chiral amines are resolved by an enzyme-catalyzed kinetic resolution. Key steps are the selective acylation of one enantiomer with isopropyl methoxyacetate, separation of the resulting amide from the unreacted antipode, and finally amide hydrolysis. The process proceeds with excellent selectivity and is highly flexible with regard to substrates.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据