Review
Polymer Science
Aymeric Genest, Daniel Portinha, Emmanuel Pouget, Khalid Lamnawar, Francois Ganachaud, Etienne Fleury
Summary: Supramolecular zwitterionic silicones were synthesized by aza-Michael reaction between acrylic acid and amine-functional polydimethylsiloxanes. The study showed that the aza-Michael addition proceeded smoothly under mild conditions, resulting in the formation of monoadducts, di-adducts, and residual amine. The assembly of zwitterionic moieties led to an increase in viscosity and phase separation, with the observation of an additional glass transition at -40 degrees C.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Sadhanendu Samanta, Jin Cui, Hidetoshi Noda, Takumi Watanabe, Masakatsu Shibasaki
Summary: In this study, a gram-scale syn-selective asymmetric vinylogous addition of butenolides to chromones was developed using an Al-Li-BINOL (ALB) complex catalyst. The reaction showed high diastereoselectivity with ratios up to 20:1 and enantioselectivity of 84-98% for various substrate combinations. This method is complementary to previous reports and improves selectivity for several chromones. Computational studies support the role of ALB as a bifunctional catalyst in this reaction and provide insights into the origin of the observed stereoselectivity.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Sadhanendu Samanta, Jin Cui, Hidetoshi Noda, Takumi Watanabe, Masakatsu Shibasaki
Summary: A gram-scale syn-selective asymmetric vinylogous addition of butenolides to chromones, catalyzed by an Al-Li-BINOL (ALB) complex, was developed in this study. The diastereoselectivity reached 20:1 with 84-98% ee for various combinations of substrates. This protocol complements previous methods and improves selectivity for multiple chromones.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Materials Science, Multidisciplinary
Witsanu Sombat, Panassilp Authai, Panuwat Padungros, Voravee P. Hoven
Summary: Micellar systems have been recognized as effective nanoreactors for performing chemical reactions in aqueous solutions. This research developed nanoreactors from polymeric micelles, in which organic substrates were encapsulated and stabilized. The micellar nanoparticles assembled from PBAM-ran-PHPAM were spherical and well-dispersed in water, with a diameter of less than 170 nm. Thia-Michael addition reactions in the presence of the PBAM26-ran-PHPAM copolymer resulted in high conversions and isolated yields of the Michael adducts. The micellar nanoreactors were also reusable up to 10 times with a high reaction conversion of 75%.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Organic
Sanjay Singh, Ravi Saini, Ravi P. Singh
Summary: An unprecedented organocatalyzed asymmetric vinylogous Michael reaction with excellent enantiomeric ratio and yield has been reported. The remarkable selectivity is attributed to the hydrogen bonding ability of the catalyst. The reaction is versatile and practical for the synthesis of various gamma-functionalized coumarin derivatives.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Polymer Science
Ralfs Pomilovskis, Inese Mierina, Anda Fridrihsone, Mikelis Kirpluks
Summary: In this study, new polymer materials were obtained by using previously developed acetoacetates and different bio-based monomers. These polymers have comparable qualities to polyurethanes without the need for hazardous materials or reactions under harsh conditions.
Article
Multidisciplinary Sciences
Chayanid Ongpipattanakul, Shi Liu, Youran Luo, Satish K. Nair, Wilfred A. van der Donk
Summary: The addition of Cys to dehydroalanine (Dha) and dehy-drobutyrine (Dhb) in both eukarya and bacteria plays important roles in various biological processes. In bacteria, this addition is catalyzed by lanthipeptide cyclases (LanC) proteins to produce lanthipeptides. In eukarya, the addition of Cys in glutathione to Dha/Dhb is catalyzed by eukaryotic LanC-like (LanCL) enzymes to protect cellular proteome. The crystal structures of human LanCL1 enzyme complexed with different ligands reveal the mechanism of the enzyme-catalyzed thia-Michael addition involving zinc ion activation, protonation of enolate intermediate, and stabilization of negative charge.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Chemistry, Multidisciplinary
Yong-Chao Ming, Xue-Jiao Lv, Ying-Han Chen, Yan-Kai Liu
Summary: A highly selective cascade process is demonstrated based on enantioselective iminium-catalyzed conjugate addition of 2-hydroxycinnamaldehydes and 2-oxocarboxylic esters. Normal cinnamaldehydes do not show reactivity under the same reaction conditions. Bridged bicyclic ketals are synthesized, bearing stereocenters on both the bridge carbon and bridgehead ketal carbon.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Wen-Bo Yao, Xuan-Sheng Xie, Jun-Nan Liu, Jian-Wu Xie
Summary: A cascade spiroannulation of 2-mercaptoquinoline-3-carbaldehydes with alpha,alpha-dicyanoalkenes and alpha-bromocarbonyl compounds was investigated, providing diverse spiro-fused heterocyclic compounds with potential biological activities.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Agricultural Engineering
Arnis Abolins, Darta Eihe, Ralfs Pomilovskis, Anda Fridrihsone, Mikelis Kirpluks
Summary: Rapeseed oil was used as a starting material to synthesize a Michael donor for the nucleophilic polymerization via Michael reaction. Four different bio-polyols were synthesized for the synthesis of the Michael donor monomer. The transesterification reaction introduced acetoacetate functional groups into the structure of the bio-polyols. The acetoacetate-functionalized bio-polyols and commercially available trimethylolpropane triacrylate were used to obtain bio-based polymers via carbon-Michael reaction. The properties of the developed polymers were analyzed using various testing apparatus.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Applied
Laura A. Bryant, Kenneth Shankland, Hannah E. Straker, Callum D. Johnston, Nicholas R. Lees, Alexander J. A. Cobb
Summary: The article describes a rare organocatalytic intramolecular cyclization of resorcinols with a high enantioselectivity using a specific organocatalyst. The obtained bicyclic resorcinols show excellent utility in the synthesis of cannabinoid-like compounds, and exhibit anticonvulsant activity.
ADVANCED SYNTHESIS & CATALYSIS
(2021)
Article
Chemistry, Organic
Xiao-Yun Li, Yan Liu, Bing Yu
Summary: A metal-free and base-free cyclization reaction was developed for the synthesis of diverse polyheterocyclic-fused quinoline-2-thiones. This protocol offers the advantages of using a green solvent, no requirement for a metal and base, short reaction time consumption, and facile isolation via simple filtration. Furthermore, it demonstrates outstanding synthetic scalability.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Nayoung Ko, Jeonghyun Min, Junghyea Moon, Nuraimi Farwizah Ismail, Kyeongwon Moon, Pargat Singh, Neeraj Kumar Mishra, Wonsik Lee, In Su Kim
Summary: The rhodium(III)-catalyzed conjugate addition of fi-trifluoromethylated enones with quinoline N-oxides for the site-selective incorporation of a trifluoromethyl group into biologically active molecules and pharmaceuticals has been demonstrated. The reaction shows excellent functional group tolerance and synthetic applicability, making it a valuable tool for gram-scale experiments and coupling product transformations.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Polymer Science
Junyi Chen, Xutao Ma, Kevin J. Edgar
Summary: This study presents a simple method for preparing polysaccharide conjugates, introducing different functional groups onto polysaccharides through thiol-Michael addition reactions. Among the conjugates, those bearing quaternary ammonium salts demonstrate superior antimicrobial performance.
Article
Chemistry, Analytical
Yujing Zuo, Zhiming Gou, Minggang Tian, Jingting Zhan, Weiying Lin
Summary: Rapid response is an important goal in fluorescence analysis technology, but it is often uncontrollable due to the limitations of the response mechanism and detection targets. In this study, a novel catalyst PNL-Br was synthesized and successfully incorporated into fluorescence analysis, showing a higher catalytic potential in thiol-Michael addition reactions. Notably, PNL-Br was an efficient catalyst for dithiothreitol (DTT) detection by fluorescence analysis, which was the first example of a catalysis system for fluorescent probe detection reactions.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Organic
Sengodagounder Muthusamy, Muthukumar Malarvizhi, Eringathodi Suresh
Summary: An efficient strategy for the synthesis of 3,4-dihydro-2H-1,3-thiazines/3,4-dihydro-2H-1,3-selenazines from propargylic alcohols and thioamides/thiosemicarbazones/selenamides is described, offering a convenient route to these heterocycles without the need to exclude air or moisture.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Unnati Patel, Parth Patel, Bhavesh Parmar, Abhishek Dadhania, Eringathodi Suresh
Summary: The study presents a promising Zn(II)-based coordination network material ADES-3 for efficient CO2 fixation and catalytic potential in the cycloaddition reaction of CO2 with epoxides. Experimental results demonstrate that ADES-3 shows good performance in terms of synthetic chemistry and thermal stability, and can be reused for up to four catalytic cycles with successful retention of activity.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Organic
Harshvardhan Singh, Chiranjit Sen, Eringathodi Suresh, Asit B. Panda, Subhash C. Ghosh
Summary: This atom-economical and efficient route for the direct amidation and amination of aryl C-H bonds using the synthesized recyclable heterogeneous Cu-MnO catalyst shows excellent results with good to excellent yields under mild conditions; the catalyst can be reused several times without significant loss of reactivity, demonstrating its environmental friendliness and cost-effectiveness.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Sengodagounder Muthusamy, Muthukumar Malarvizhi, Eringathodi Suresh
Summary: The AlCl3-catalyzed oxidative cyclization of thiosemicarbazones/triazolothiones with propargylic alcohols provides a diverse set of triazolothiazines in good yields. This synthetic approach offers the advantages of shorter duration at room temperature and atom economical synthesis in an open-air environment.
Article
Biochemistry & Molecular Biology
Rakesh Nirmalkar, E. Suresh, N. Felix, A. Kathirvelpandian, Mir Ishfaq Nazir, Amit Ranjan
Summary: This study focuses on the green synthesis of iron nanoparticles using plant extracts and investigates their properties and applications. Results showed that iron nanoparticles were successfully synthesized using Sargassum wightii extract, and the nanoparticles had negative and positive charges. Feeding the nano-iron supplemented diet to Etroplussuratensis fingerlings significantly improved their growth and serum biochemical profile.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
A. Rathipriya, A. Kathirvelpandian, S. A. Shanmugam, A. Uma, E. Suresh, N. Felix
Summary: In this study, molecular signatures and character-based methods were used to identify and classify fish in Pulicat Lake. By using 16S rRNA barcode analysis, 29 species of fish were successfully identified, and character-based molecular diagnostic keys were developed.
INDIAN JOURNAL OF ANIMAL RESEARCH
(2022)
Article
Chemistry, Physical
V Raju, E. Suresh, Boorla Shashikanth, B. Jagadeesh, Azmeera Srinivas, T. Ch Anil Kumar, Nellore Manoj Kumar
Summary: In this paper, a Double Material Gate Tunnel Field Effect Transistor (DG-TFET) is proposed to address the challenge of low on current in TFET. By using two different semiconductor materials and a symmetrical gate structure, DG-TFET improves drain current and transconductance characteristics, achieving significant improvement in on/off current ratio and on current.
Article
Nanoscience & Nanotechnology
Parth Patel, Unnati Patel, Bhavesh Parmar, Abhishek Dadhania, Eringathodi Suresh
Summary: Developing a novel heterogeneous catalyst for regioselective ring-opening reactions of spiro-epoxyoxindoles has significant importance in the pharmaceutical industry. In this study, a chiral-phase pure Zn-based metal-organic framework (MOF) was synthesized and shown to efficiently catalyze the formation of beta-alkoxy/beta-hydroxy alcohols. The catalyst exhibited excellent activity and stability, and the catalytic products were confirmed by single-crystal X-ray diffraction (SXRD) analysis.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Bhavesh Parmar, Parth Patel, Gopala Ram Bhadu, Eringathodi Suresh
Summary: Two isostructural MOFs with different ligands were synthesized and their catalytic activities were compared. One of the MOFs showed better catalytic performance and both MOFs exhibited good reusability.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Review
Microbiology
M. P. Arulmoorthy, R. Vijayan, K. Sinduja, E. Suresh, S. Vasudevan
Summary: Over the past three decades, the shrimp industry has been affected by numerous destructive diseases, including viral, bacterial, and parasitic diseases. A new emerging viral disease, Decapod iridescent virus 1 (DIV1), is now threatening the shrimp culture industry in Asia. This review article discusses the significance of DIV1 and its implications for global aquaculture.
ARCHIVES OF MICROBIOLOGY
(2022)
Article
Fisheries
M. Anjusha, S. Prakash, A. Kathirvelpandian, M. Sakthivel, N. Kalaiselvi, E. Suresh
Summary: This study aimed to assess the repeatability and phenotypic correlation of reproductive traits in captive zebrafish. Breeding trials were conducted on 10 breeding pairs, and data on fecundity, fertility, hatchability, and survival rate were recorded. The results showed moderate repeatability values for most reproductive traits, except for the hatchability of fertilised eggs. The phenotypic correlation analysis indicated significant correlations between fertility and hatchability of fertilised eggs, hatchability of total eggs, survival rate of total eggs, and survival rate of larvae.
INDIAN JOURNAL OF FISHERIES
(2023)
Article
Chemistry, Organic
Sengodagounder Muthusamy, Muthukumar Malarvizhi, Eringathodi Suresh
Summary: The study presents an unambiguous and precise method for the synthesis of 3,1-benzoxathiin-4-ones/1,3-benzodioxin-4-ones using propargylic alcohols and salicylic/thiosalicylic acids under catalyst-free and open-air conditions. This strategy is shown to be quite general, yielding benzoxathiinones/benzodioxinones in good amounts with various 2-mercapto and 2-hydroxybenzoic acids.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Unnati Patel, Bhavesh Parmar, Parth Patel, Abhishek Dadhania, Eringathodi Suresh
Summary: Two mixed ligand MOFs with identical two-dimensional network topology were synthesized and characterized, showing potential for efficient dye adsorption and catalytic applications. ADES-1 demonstrated rapid and efficient adsorption of various dye molecules, with a preference for methyl violet, and also showed good stability and reusability for potential functional material applications.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
D. Basavaraja, M. S. Ajay Krishna, Jagadeesh Krishnan, C. S. Athira, R. R. Amrutha, Eringathodi Suresh, Sasidhar B. Somappa
Summary: The research achieved base assisted divergent reactivity of isatins and allenoates, leading to diastereoselective spirofuran oxindoles and gamma-functionalized allenoates. This method offers access to biologically relevant functionalized oxindole scaffolds with excellent substrate scope under mild reaction conditions.
CHEMICAL COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Jijo Johnson, Ekata Saha, Ashis Chhetri, Eringathodi Suresh, Joyee Mitra
Summary: The growth in industrialization has led to the continuous discharge of organic dyes polluting the aquatic ecosystem. A biocompatible and cost-effective adsorbent called BMA has been developed for efficient removal of dyes from wastewater, showing high adsorption capacity and reusability.
ACS APPLIED POLYMER MATERIALS
(2021)