期刊
SYNLETT
卷 -, 期 19, 页码 2905-2907出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259029
关键词
N-formylation; amines; organic reactions in water; triethyl orthoformate
资金
- Institute for Advanced Studies in Basic Sciences (IASBS) Research Council [G2009IASBS120]
A simple, efficient, scaleable process has been developed for the N-formylation amines in water. Treatment of amines with triethyl orthoformate in water at reflux under neutral conditions without any additives gives the corresponding N-formyl derivatives in good yields.
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