Studies of the metabotropic glutamate receptor 5 radioligand [11C]ABP688 withN-acetylcysteine challenge in rhesus monkeys

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

(2014) Olivia Dean et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Targeting glutamate system for novel antipsychotic approaches: Relevance for residual psychotic symptoms and treatment resistant schizophrenia

(2012) Andrea de Bartolomeis et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Recent Advances in Imaging of Dopaminergic Neurons for Evaluation of Neuropsychiatric Disorders

(2012) Lie-Hang Shen et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Combining PET Biodistribution and Equilibrium Dialysis Assays to Assess the Free Brain Concentration and BBB Transport of CNS Drugs

(2012) Roger N Gunn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Optimization of PET–MR registrations for nonhuman primates using mutual information measures: A Multi-Transform Method (MTM)

(2012) Christine M. Sandiego et al.   NEUROIMAGE

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

(2012) Aubin Michalon et al.   NEURON

Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine produces antidepressant effects in rats: Role of brain-derived neurotrophic factor

(2012) C.Y. Liu et al.   NEUROSCIENCE

Reduced Metabotropic Glutamate Receptor 5 Density in Major Depression Determined by [11C]ABP688 PET and Postmortem Study

(2011) Alexandra Deschwanden et al.   AMERICAN JOURNAL OF PSYCHIATRY

Imaging Changes in Glutamate Transmission In Vivo with the Metabotropic Glutamate Receptor 5 Tracer [11C] ABP688 and N-Acetylcysteine Challenge

(2011) Nobumi Miyake et al.   BIOLOGICAL PSYCHIATRY

1H-[13C]-Nuclear Magnetic Resonance Spectroscopy Measures of Ketamine's Effect on Amino Acid Neurotransmitter Metabolism

(2011) Golam M.I. Chowdhury et al.   BIOLOGICAL PSYCHIATRY

In vivo positron emission tomography imaging with [11C]ABP688: binding variability and specificity for the metabotropic glutamate receptor subtype 5 in baboons

(2011) Christine DeLorenzo et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

in vivo Variation in Metabotropic Glutamate Receptor Subtype 5 Binding Using Positron Emission Tomography and [11C]ABP688

(2011) Christine DeLorenzo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

mGluRs Modulate Strength and Timing of Excitatory Transmission in Hippocampal Area CA3

(2011) Kathleen E. Cosgrove et al.   MOLECULAR NEUROBIOLOGY

Positive Allosteric Modulators of Type 5 Metabotropic Glutamate Receptors (mGluR5) and Their Therapeutic Potential for the Treatment of CNS Disorders

(2011) Richard M. Cleva et al.   MOLECULES

Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links

(2011) D. K. Sokol et al.   NEUROLOGY

New perspectives in glutamate and anxiety

(2011) Carlos Riaza Bermudo-Soriano et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Glutamatergic Targets for Enhancing Extinction Learning in Drug Addiction

(2010) R. M. Cleva et al.   Current Neuropharmacology

In vivo and in vitro Validation of Reference Tissue Models for the mGluR5 Ligand [11C]ABP688

(2010) David Elmenhorst et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice

(2010) Hwei-Hsien Chen et al.   PSYCHOPHARMACOLOGY

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Direct Interaction Enables Cross-talk between Ionotropic and Group I Metabotropic Glutamate Receptors

(2008) Julie Perroy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY