Article
Multidisciplinary Sciences
M. B. Muijzer, C. M. W. Hoven, L. E. Frank, G. Vink, R. P. L. Wisse
Summary: Machine learning was used to explore the complex patterns of graft detachment after endothelial corneal transplantation surgery and evaluate the effects of practice pattern modulations. The results can assist surgeons in reviewing their practice patterns and generate hypotheses for empirical research on the origins of graft detachments.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Antonio Ballesteros-Sanchez, Jorge Peraza-Nieves, Anna Casablanca-Pinera, Marina Rodriguez-Calvo-De-Mora, Saray Catalan-Coronado, Josep Torras-Sanvicens, Davide Borroni, Jose-Maria Sanchez-Gonzalez, Carlos Rocha-De-Lossada
Summary: This study compared corneal densitometry patterns between DMEK and DSAEK procedures. The results showed that DMEK had significantly lower corneal density and CD values compared to DSAEK. Additionally, DMEK showed better BCDVA, CCT, and GT values.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Dana D. Huh, Chen Dun, Michael J. Fliotsos, Bennie H. Jeng, Christopher G. Stoeger, Martin Makary, Fasika A. Woreta, Meraf Wolle, Divya Srikumaran
Summary: The purpose of this study was to determine national-level trends in early regraft rates and examine patient-level and surgeon-level characteristics associated with early regrafts. A retrospective cohort study was conducted using Medicare claims data. The study found no significant increases in early regraft rates over the past decade in the United States, and identified factors such as patient demographics and surgical location that were associated with early regrafts.
Article
Ophthalmology
Harminder S. Dua, Rui Freitas, Youssef Sadek, Darren S. J. Ting, Mario Nubile, Imran Mohammed, Dalia G. Said
Summary: The study aimed to determine the primary axis of Descemet's membrane scrolling and investigate the impact of oval trephination along the axis of least scrolling. Results showed that Descemet's membrane primarily scrolled along the horizontal axis, and vertically oval samples displayed minimal scrolling. Additionally, the degree of scrolling was not influenced by the distribution of elastin.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Kristof Daniel Rodler, Tamas Pregun, Bernadett Andras, Milan Tamas Pluzsik, Janos Hargitai, Agnes Kerenyi
Summary: This study reports 3 cases of posterior chamber intraocular lens dislocation into the vitreous after Descemet stripping automated endothelial keratoplasty (DSAEK), and summarizes the surgical management and outcomes.
Article
Ophthalmology
Michael Mimouni, Nir Sorkin, Jacqueline Slomovic, Eli Kisilevsky, Zale Mednick, Eyal Cohen, Tanya Trinh, Gisella Santaella, Clara C. Chan, David S. Rootman, Allan R. Slomovic
Summary: The study compared outcomes of DMEK and DSAEK in complex eyes undergoing vitrectomy. DMEK had a higher proportion of Fuchs' patients and higher rates of serious adverse events postoperatively compared to DSAEK.
CURRENT EYE RESEARCH
(2021)
Article
Ophthalmology
Giulia Coco, Hannah J. Levis, Alfredo Borgia, Davide Romano, Luca Pagano, Gianni Virgili, Stephen B. Kaye, Vito Romano
Summary: By evaluating the features of anterior segment optical coherence tomography (AS-OCT), it was found that posterior stromal ripples and detachment axial extension are the main risk factors for graft detachment worsening in Descemet's membrane endothelial keratoplasty (DMEK). Patients showing these features should be closely monitored to identify the need for re-bubbling at an early stage, thus improving surgical outcomes.
ACTA OPHTHALMOLOGICA
(2023)
Review
Ophthalmology
Masomeh Mohebbi, Mohammad Mehrpour, Amin Dehghani Sanij, Nader Mohammadi, Masoud Mirghorbani
Summary: Endothelial keratoplasty (EK) is increasingly being considered as the first intervention in treating corneal endothelial dysfunction in children. Descemet's stripping automated endothelial keratoplasty (DSAEK) is the most commonly performed procedure for pediatric patients. Despite some technical challenges, EK procedures show acceptable visual and anatomical outcomes in pediatric cases, with graft dislocation being the most common complication.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The purpose of this study was to evaluate the 15-year outcomes of Descemet stripping endothelial keratoplasty (DSEK). The results showed that DSEK provided excellent long-term visual rehabilitation and graft survival in this early cohort.
Article
Ophthalmology
Rathin Pujari, Artemis Matsou, Jane Kean, Jufen Zhang, Madhavan S. Rajan
Summary: The study found no significant difference in BSCVA and endothelial cell density between DMEK and MT-DSAEK at 24 months, with a reduced difference compared to 1-year results. Both techniques showed similar outcomes for complication rates, endothelial cell loss, and patient-reported vQoL scores.
Article
Ophthalmology
Divya Srikumaran, Hyeck-Soo Son, Charles Li, Oliver Schein, Sudeep Pramanik
Summary: This study assessed risk factors for poor visual outcomes after EK surgery. The results showed that postoperative rebubbling and repeat keratoplasties were associated with worse visual outcomes, while older age and female gender were associated with poorer visual outcomes in the FECD subgroup.
Review
Medicine, Research & Experimental
Georgios s. Dimtsas, Marilita m. Moschos
Summary: In this meta-analysis, the efficacy and safety of UT-DSAEK and DMEK were compared for the treatment of corneal endothelial failure in patients with FED or PBK. The results showed that DMEK had significantly better BSCVA at 3, 6, and 12 months postoperatively compared to UT-DSAEK. However, UT-DSAEK had a better complication profile with lower rebubbling rates.
Article
Ophthalmology
Artemis Matsou, Rathin Pujari, Hammad Sarwar, Mrinal Rana, James Myerscough, Susan M. Thomson, Girinath Nandakumar, Jufen Zhang, Madhavan S. Rajan
Summary: The study compared the outcomes of MT-DSAEK and DMEK surgeries for Fuchs dystrophy. Results showed that DMEK surgery led to significantly better BSCVA at 1, 3, 6, and 12 months postoperatively, with similar complication rates and vision-related QoL scores between the two groups.
Article
Ophthalmology
Michael J. Fliotsos, Jack A. Campbell, Ximin Li, Marie B. Engstrom, Christopher G. Stoeger, Cathy McClory, Michael S. Titus, Patrick Johnson, Kara B. Johnston, Tim Fischer, Lisa K. Brooks, Monty M. Montoya, David B. Glasser, Esen Karamursel Akpek, Divya Srikumaran
Summary: This study aimed to report trends in the prevalence of early graft failure after endothelial keratoplasty in the United States. The results showed that the proportion of early graft failures in DMEK decreased over time and was comparable with failure rates in DSAEK at the end of the study period.
Review
Ophthalmology
Marian Kiel, Julia Bing Bu, Adrian Gericke, Urs Vossmerbaeumer, Alexander K. Schuster, Norbert Pfeiffer, Joanna Wasielica-Poslednik
Summary: In patients with endothelial decompensation after PK, both DMEK and DSAEK significantly improved visual acuity. Lamellar graft survival, loss of endothelial cells, and mean rebubbling rates were similar in both groups.
Article
Ophthalmology
Marianne O. Price, Matthew T. Feng, Francis W. Price
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2018)
Article
Ophthalmology
Jonathan W. Crews, Marianne O. Price, Jeferson Lautert, Matthew T. Feng, Francis W. Price
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2018)
Article
Ophthalmology
Anand Pasari, Marianne O. Price, Matthew T. Feng, Francis W. Price
Editorial Material
Ophthalmology
Francis W. Price, Marianne O. Price
Letter
Ophthalmology
Anand Pasari, Marianne O. Price, Matthew T. Feng, Francis W. Price
Article
Ophthalmology
Kavitha Subramaniam, Marianne O. Price, Matthew T. Feng, Francis W. Price
Article
Ophthalmology
Alejandro Saint-Jean, Mark Soper, Kyle Den Beste, Shawn Iverson, Marianne O. Price, Francis W. Price
Article
Ophthalmology
Enrique S. Malbran, Francis W. Price, Joaquin E. Arganaraz Olivero, Enrique Malbran Jr, Jorge Malbran, Marcos Malbran, Leandro N. Rogel, Marianne O. Price, Carlos H. Gordillo
Article
Ophthalmology
Marianne O. Price, Denisse Pinkus, Francis W. Price
Article
Biochemistry & Molecular Biology
Taiga Miyajima, Geetha Melangath, Shan Zhu, Neha Deshpande, Shivakumar Vasanth, Bodhisattwa Mondal, Varun Kumar, Yuming Chen, Marianne O. Price, Francis W. Price, Eleanor G. Rogan, Muhammad Zahid, Ula Jurkunas
FREE RADICAL BIOLOGY AND MEDICINE
(2020)
Article
Ophthalmology
Marianne O. Price, Matthew T. Feng, Francis W. Price
Summary: The study aimed to assess whether prophylactic use of netarsudil 0.02% ophthalmic solution reduces the risk of intraocular pressure elevation associated with prolonged use of topical corticosteroids. The results showed that there was no statistically significant reduction in the risk of steroid-induced IOP elevation after corneal transplantation relative to placebo in the netarsudil group.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Review
Ophthalmology
Marianne O. Price, Jodhbir S. Mehta, Ula Jurkunas, Francis W. Price
Summary: The cornea protects and focuses incoming light for the eye. Precise control of corneal hydration by endothelial cells is vital for transparency and visual health. Advances in corneal transplantation offer new options for treating dysfunction, while research into alternative treatments continues.
PROGRESS IN RETINAL AND EYE RESEARCH
(2021)
Article
Ophthalmology
Marianne O. Price, Matthew T. Feng, Francis W. Jr Jr Price
Summary: Endothelial keratoplasty has revolutionized the treatment of corneal endothelial dysfunction, providing rapid visual rehabilitation and high standards of safety and efficacy. Advances in techniques have improved visual outcomes and facilitated donor tissue preparation, but a shortage of human donor corneas remains a challenge, driving the search for alternatives to traditional keratoplasty. More work is needed to expand the donor supply, address adoption barriers, optimize graft survival, and improve refractive predictability.
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The off-label use of netarsudil 0.02% showed significant reduction in central corneal thickness and improvement in scotopic corrected distance visual acuity in patients with Fuchs dystrophy. Further studies are needed to fully assess patient satisfaction and compare netarsudil with other treatment options.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Marianne O. Price, Francis W. Price
Summary: The purpose of this study was to evaluate the 15-year outcomes of Descemet stripping endothelial keratoplasty (DSEK). The results showed that DSEK provided excellent long-term visual rehabilitation and graft survival in this early cohort.
