Article
Oncology
Petronilla Staubach, Anton Scharl, Atanas Ignatov, Olaf Ortmann, Elisabeth C. Inwald, Thomas Hildebrandt, Michael Gerken, Monika Klinkhammer-Schalke, Sophia Scharl, Thomas Papathemelis
Summary: The study demonstrates that indocyanine green can be as effective as the radioisotope for SLNB in early breast cancer patients, even among those who have undergone NACT. This offers a potential alternative to overcome the limitations associated with radioactive Technetium(99m) colloid, such as limited availability, high costs, and radioactivity exposure.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Surgery
Claudia A. Bargon, Anne Huibers, Danny A. Young-Afat, Britt A. M. Jansen, Inne H. M. Borel-Rinkes, Jules Lavalaye, Henk-Jan Van Slooten, Helena M. Verkooijen, Christiaan F. P. van Swol, Annemiek Doeksen
Summary: This study compared the detection rate of indocyanine green (ICG)-fluorescent imaging and Tc-99m-nanocoilloid for sentinel lymph node (SLN)-mapping in breast cancer patients. The results showed that ICG-fluorescence had a higher detection rate than Tc-99m-nanocoilloid, and both methods had equal detection rates for pathological lymph nodes. The study suggests that ICG-fluorescence may be a safe and effective alternative for SLNB in early-stage breast cancer patients.
Article
Medicine, General & Internal
Ilhan Tasdoven, Hakan Balbaloglu, Rabiye Uslu Erdemir, Burak Bahadir, Cakmak Guldeniz Karadeniz
Summary: Axillary staging is an important issue in the management of breast cancer. This study used triple mapping to assess the metastatic involvement of axillary reverse mapping (ARM) nodes after neoadjuvant systemic therapy (NST). The results showed a significant overlap between arm and breast draining nodes, which may explain the development of lymphedema in patients even after treatment.
Article
Oncology
Leah A. Marsh, Emeline M. Aviki, Jason D. Wright, Ling Chen, Nadeem Abu-Rustum, Ritu Salani
Summary: This study estimates the annual cost of wasted indocyanine green (ICG) used for sentinel lymph node mapping in patients with endometrial cancer. The findings show that the current manufactured vial size of ICG leads to wasted costs exceeding $2 million for hospitals and $13.3-$17.7 million for patients annually. The study suggests packaging ICG in smaller vials to avoid drug waste and financial impact.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Surgery
Zi-Han Wang, Tian-Ran Gang, Shan-Shan Wu, Can Lu, Guo-Xuan Gao, Wei Xu, Guo-Qian Ding, Xiang Qu, Zhong-Tao Zhang
Summary: This study explored the surgical safety and reliability of combining indocyanine green and carbon nanoparticles with single-port endoscopic-sentinel lymph node biopsy. The novel technique showed similar detection rate and number of sentinel lymph nodes compared to conventional sentinel lymph node biopsy. It is as safe and reliable as the conventional method but with the aesthetic advantage of only one incision.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Chaobin Wang, Fuzhong Tong, Yingming Cao, Peng Liu, Bo Zhou, Hongjun Liu, Lin Cheng, Miao Liu, Jiajia Guo, Fei Xie, Houpu Yang, Siyuan Wang, Yuan Peng, Shu Wang
Summary: The combination of ICG and MB showed a high detection rate and accuracy in SLNB for early breast cancer patients, with low rates of recurrence and lymphedema.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Surgery
Kenjiro Jimbo, Uta Nakadaira, Chikashi Watase, Takeshi Murata, Sho Shiino, Shin Takayama, Akihiko Suto
Summary: The combination of radioisotopes and indocyanine green enables accurate detection of metastatic sentinel lymph nodes in breast cancer patients. However, there are discordances in sentinel lymph node reactivity between different tracers. Therefore, axillary lymph node dissection should be considered in these cases to ensure accurate nodal staging.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Materials Science, Biomaterials
Ahmed A. Elbatrawy, Da Sol Lee, Sang Bong Lee, Hui-Jeon Jeon, Sijoon Lee, Kyung-ku Kang, Soo-Eun Sung, Ye Ri Han, Sung Jin Cho, Dong-Su Kim, Kil Soo Kim, Ghilsoo Nam, Yong Hyun Jeon
Summary: KSNP117, a novel quinoline-based fluorescent probe, shows great potential as a biocompatible and highly sensitive imaging agent for the accurate detection of sentinel lymph nodes, with no adverse effects on cell proliferation and excellent serum stability.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Multidisciplinary
Wenjing Cheng, Xiangbai Wu, Shi Yu, Chengwei Zhang, Yinhong Song, Xinzhi Li, Xiang Yu
Summary: This study developed a new technique for sentinel lymph node imaging using macrophage cell membrane-camouflaged ICG-loaded biomimetic nanoparticles, which achieved accurate lymph node imaging.
Article
Materials Science, Biomaterials
Ye Ri Han, Da-Sol Lee, Sang Bong Lee, Hui-Jeon Jeon, Sijoon Lee, Soo-Eun Sung, Chang-Hee Lee, Sung Jin Cho, Kil Soo Kim, Dong-Su Kim, Yong Hyun Jeon
Summary: Novel phenaleno isoquinolinium-based fluorescent agents have been developed for sensitive detection of sentinel lymph nodes, showing potential for clinical applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Surgery
Yong Xu, Songlin Yuan, Mingtao Chen, Ke Gong, Youzhong Liu, Shengyun Li, Fang Xiong, Yuejun Pan, Jiyao Cao, Jia Gong, Na Luo
Summary: This study evaluated the efficacy of combining indocyanine green (ICG) with methylene blue staining in sentinel lymph node biopsy (SLNB) for breast cancer. The results showed that the combination of ICG and methylene blue had a higher detection rate, accuracy, and sensitivity compared to using methylene blue alone or ICG alone. Therefore, the combination of ICG and methylene blue is a promising and effective tracing strategy for SLNB in breast cancer.
Article
Oncology
Keyu Jiang, Binlin Luo, Zuoqiong Hou, Chujun Li, Huiming Cai, Jian Tang, Gang Yao
Summary: The study demonstrates that the ICG fluorescent imaging system can improve the detection rate of SLNs in acral malignant melanoma patients. Furthermore, combining ICG with MB is more effective in enhancing SLN detection rates compared to using ICG alone.
ANNALS OF TRANSLATIONAL MEDICINE
(2021)
Article
Oncology
David Cibula, Martina Borcinova, Simone Marnitz, Jiri Jarkovsky, Jaroslav Klat, Radovan Pilka, Aureli Torne, Ignacio Zapardiel, Almerinda Petiz, Laura Lay, Borek Sehnal, Jordi Ponce, Michal Felsinger, Octavio Arencibia-Sanchez, Peter Kascak, Kamil Zalewski, Jiri Presl, Alicia Palop-Moscardo, Solveig Tingulstad, Ignace Vergote, Mikulas Redecha, Filip Fruhauf, Christhardt Koehler, Roman Kocian
Summary: The study found that replacing standard PLND with bilateral SLN biopsy in cervical cancer surgical treatment does not eliminate the risk of mild to moderate LLL, which develops regardless of the number of SLNs removed.
Article
Medicine, General & Internal
Roberto Cirocchi, Giulio Metaj, Michela Cicoletti, Fabrizio Arcangeli, Angelo De Sol, Giulia Poli, Paolo Bruzzone, Sara Gioia, Christos Anagnostou, Fabio Loreti, Simona Francesconi, Linda Ricci, Maria Elena Laurenti, Andrea Capotorti, Marco Artico, Vito D'Andrea, Brandon Michael Henry, Piergiorgio Fedeli, Luigi Carlini
Summary: Studies have shown significant heterogeneity in lymphatic drainage patterns of different cutaneous melanomas, emphasizing the need for multiple imaging evaluations in critical skin areas. The use of fluorescence lymphography with indocyanine green has greatly improved visualization at a microscopic level. It is crucial to combine SPET-CT scans with lymphoscintigraphy preoperatively and perform additional evaluations with indocyanine green intraoperatively to accurately identify sentinel nodes and reduce false negative rates.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Qiu-hui Yang, Xiang-jian Zhang
Summary: Near-infrared fluorescence imaging using Indocyanine green (ICG) has been shown to improve sentinel lymph node biopsy (SLNB) efficiency. This study evaluated the effectiveness of combining ICG and methylene blue (MB) in SLNB for breast cancer patients. The combination of ICG and MB resulted in higher detection rates and the ability to identify more lymph nodes compared to MB alone.
Article
Food Science & Technology
Sophal Cheat, Juliana R. Gerez, Juliette Cognie, Imourana Alassane-Kpembi, Ana Paula F. L. Bracarense, Isabelle Raymond-Letron, Isabelle P. Oswald, Martine Kolf-Clauw
Article
Agriculture, Dairy & Animal Science
Sebastien Elis, Sandrine Freret, Alice Desmarchais, Virginie Maillard, Juliette Cognie, Eric Briant, Jean-Luc Touze, Mickael Dupont, Philippe Faverdin, Veronique Chajes, Svetlana Uzbekova, Philippe Monget, Joelle Dupont
ANIMAL REPRODUCTION SCIENCE
(2016)
Article
Food Science & Technology
Sophal Cheat, Philippe Pinton, Anne-Marie Cossalter, Juliette Cognie, Maria Vilarino, Patrick Callu, Isabelle Raymond-Letron, Isabelle P. Oswald, Martine Kolf-Clauw
FOOD AND CHEMICAL TOXICOLOGY
(2016)
Article
Agriculture, Dairy & Animal Science
Sebastien Elis, Alice Desmarchais, Sandrine Freret, Virginie Maillard, Valerie Labas, Juliette Cognie, Eric Briant, Celine Hivelin, Joelle Dupont, Svetlana Uzbekova
JOURNAL OF DAIRY SCIENCE
(2016)
Article
Reproductive Biology
Rodrigo Diego, Cecile Douet, Fabrice Reigner, Thierry Blard, Juliette Cognie, Stefan Deleuze, Ghylene Goudet
Article
Endocrinology & Metabolism
Claude Fabre-Nys, Juliette Cognie, Laurence Dufourny, Meriem Ghenim, Stephanie Martinet, Olivier Lasserre, Didier Lomet, Robert P. Millar, Satoshi Ohkura, Yuta Suetomi
Article
Multidisciplinary Sciences
Martine Batailler, Didier Chesneau, Laura Derouet, Lucile Butruille, Stephanie Segura, Juliette Cognie, Joelle Dupont, Delphine Pillon, Martine Migaud
SCIENTIFIC REPORTS
(2018)
Article
Multidisciplinary Sciences
Maxime Reverchon, Christelle Rame, Juliette Cognie, Eric Briant, Sebastien Elis, Daniel Guillaume, Joelle Dupont
Article
Developmental Biology
S. Coyral-Castel, C. Rame, J. Cognie, J. Lecardonnel, S. Marthey, D. Esquerre, C. Hennequet-Antier, S. Elis, S. Fritz, M. Boussaha, F. Jaffrezic, J. Dupont
Article
Biochemistry & Molecular Biology
Danielle Monniaux, Carine Genet, Virginie Maillard, Peggy Jarrier, Hans Adriaensen, Christelle Hennequet-Antier, Anne-Lyse Laine, Corinne Laclie, Pascal Papillier, Florence Plisson-Petit, Anthony Estienne, Juliette Cognie, Nathalie di Clemente, Rozenn Dalbies-Tran, Stephane Fabre
CELLULAR AND MOLECULAR LIFE SCIENCES
(2020)
Article
Endocrinology & Metabolism
Raymond Nowak, Frederic Levy, Elodie Chaillou, Fabien Cornilleau, Juliette Cognie, Pierre-Guy Marnet, Peter D. Williams, Matthieu Keller
Summary: The study found that both delayed access to the mother's udder and administration of an OT receptor antagonist altered the onset of mother preference in newborn lambs. This suggests that central OT facilitates the development of filial attachment through its release during suckling.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Veterinary Sciences
Juliette Cognie, Sandrine Freret, Lea Lansade, Celine Parias, Philippe Barriere, Amandine Gesbert, Fabrice Reigner, Stefan Deleuze
Summary: This study compares castration at 3 days and 18 months of age in Welsh ponies and assesses their subsequent development. The results show that early castration does not interfere with the morphological and behavioral development of ponies.
EQUINE VETERINARY JOURNAL
(2023)
Article
Veterinary Sciences
Ambre Baillou, Nathalie Kasal-Hoc, Celine Barc, Juliette Cognie, Anne Pinard, Jeremy Pezant, Julie Schulthess, Pauline Peltier-Pain, Sonia Lacroix-Lamande, Fabrice Laurent
Summary: Researchers have developed a new method for an initial in vivo screen of promising compounds against neonatal diseases, reducing the use of experimental animals. The method involves the use of newborn lambs delivered by cesarean section to evaluate the compounds' ability to stimulate immune responses and limit Cryptosporidium development.
VETERINARY SCIENCES
(2021)
Article
Agriculture, Dairy & Animal Science
V. Paulmier, M. Faure, D. Durand, A. Boissy, J. Cognie, A. Eschalier, E. M. C. Terlouw
INRA PRODUCTIONS ANIMALES
(2015)
Article
Biochemistry & Molecular Biology
Didier Lomet, Juliette Cognie, Didier Chesneau, Emeric Dubois, David Hazlerigg, Hugues Dardente
CELLULAR AND MOLECULAR LIFE SCIENCES
(2018)