Article
Surgery
Qiangxing Chen, Rou Zhou, Jiefeng Weng, Yueyuan Lai, Hui Liu, Jiao Kuang, Shuai Zhang, Zhaofeng Wu, Wen Wang, Weili Gu
Summary: ICG FC allows real-time identification of extrahepatic bile ducts, with optimal effects achieved by administering 10 mg of ICG injections 10 to 12 hours before surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Ciro Esposito, Daniele Alberti, Alessandro Settimi, Silvia Pecorelli, Giovanni Boroni, Beatrice Montanaro, Maria Escolino
Summary: The study demonstrated the effectiveness of using the new RUBINA (TM) technology for performing intra-operative ICG fluorescent cholangiography during laparoscopic cholecystectomy in pediatric patients, allowing identification of biliary and vascular anatomical anomalies.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Jun Kit Koong, Gaik Huey Ng, Kamarajan Ramayah, Peng Soon Koh, Boon Koon Yoong
Summary: The study found that ICGFC can reduce the time to achieve CVS in LC, especially in cases with higher difficulty levels, but the results were not statistically significant. No major complications were observed in the study.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Surgery
Fernando Dip, Rene Aleman, Joel S. Frieder, Camila Ortiz Gomez, Emanuele Lo Menzo, Samuel Szomstein, Raul J. Rosenthal
Summary: This study describes the critical steps in performing NIFC during LC, such as preoperative administration of indocyanine green, exposure of the hepatoduodenal ligament, initial anatomical evaluation, identification of critical structures, time-out and evaluation of the liver bed. Routine use of NIFC can provide better visualization of extrahepatic biliary structures and reduce the incidence of BDI during LC.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Medicine, General & Internal
Lidia Castagneto-Gissey, Maria Francesca Russo, Alessandra Iodice, James Casella-Mariolo, Angelo Serao, Andrea Picchetto, Giancarlo D'Ambrosio, Irene Urciuoli, Alessandro De Luca, Bruno Salvati, Giovanni Casella
Summary: Fluorescence cholangiography with indocyanine green (ICG) can help to identify extrahepatic biliary anatomy during laparoscopic cholecystectomy. Direct gallbladder ICG injection (IC-ICG) and intravenous ICG administration (IV-ICG) were compared, with IV-ICG showing better delineation of the duodenum and common hepatic duct, and significantly shorter overall operative time. In addition, IV-ICG achieved a higher bile duct-to-liver contrast by avoiding hepatic fluorescence.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Surgery
Ciro Esposito, Alessandro Settimi, Mariapina Cerulo, Maria Escolino
Summary: This study compared the results of laparoscopic cholecystectomy (LC) with and without the use of indocyanine green fluorescent cholangiography (ICG-FC), finding that ICG-FC significantly reduced operative time and improved safety. ICG-guided fluorescence provided excellent real-time visualization of the extrahepatic biliary tree, minimizing the risk of bile duct injuries.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Oncology
Marcus J. Brookes, Corey D. Chan, Fabio Nicoli, Timothy P. Crowley, Kanishka M. Ghosh, Thomas Beckingsale, Daniel Saleh, Petra Dildey, Sanjay Gupta, Maniram Ragbir, Kenneth S. Rankin
Summary: Sarcomas are rare cancers that often require surgery for treatment. By using a harmless dye called indocyanine green before surgery and a near-infrared camera during the operation, surgeons were able to better identify and remove tumours, reducing the chances of recurrence.
Review
Surgery
Sioh Huang Lim, Hui Ting Alyssa Tan, Vishal G. Shelat
Summary: ICG-FC is safe and improves visualization of the common hepatic duct (CHD) compared to IOC in minimal access cholecystectomy.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Surgery
Chengfan Xu, Maohui Yin, Haitao Wang, Ping Jiang, Zhiyong Yang, Yueming He, Zhonglin Zhang, Zhisu Liu, Bo Liao, Yufeng Yuan
Summary: This study analyzed and compared the surgical outcomes of fluorescent and conventional laparoscopy in cholecystectomy, and evaluated the value of near-infrared fluorescent cholangiography. The results showed that ICG-assisted fluorescence can shorten operative time, length of stay, reduce blood loss, and decrease adverse reactions in difficult cases.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Fernando Pardo Aranda, Clara Gene Skrabec, Jaime Lopez-Sanchez, Alba Zarate Pinedo, Francisco Espin Alvarez, Manel Cremades Perez, Jordi Navines Lopez, Christian Herrero Vicente, Laura Vidal Pineiro, Esteban Cugat Andorra
Summary: This study aimed to analyze and simplify the optimal dose and time of intravenous indocyanine green (ICG) administration for identifying the cystic duct and the common bile duct (CBD). A consecutive series of 146 patients were prospectively analyzed and divided into three groups based on the timing of ICG administration and two groups based on the dose of ICG. The results showed that the CBD was better visualized when ICG was administered at the induction of anesthesia or 2-6 hours before surgery, and when a dose of 1cc was used. Therefore, the optimal choice is to administer 2.5mg of ICG 2-6 hours before surgery, but administering ICG 30 minutes before surgery is sufficient for adequate visualization of biliary structures.
DIGESTIVE AND LIVER DISEASE
(2023)
Article
Neurosciences
Jun Muto, Yutaka Mine, Yuya Nishiyama, Kazuhiro Murayama, Seiji Yamada, Daijiro Kojima, Motoharu Hayakawa, Kazuhide Adachi, Mitsuhiro Hasegawa, John Y. K. Lee, Yuichi Hirose
Summary: This study aimed to visualize meningiomas and dural tails intraoperatively using delayed-window indocyanine green (ICG) technique. The results showed that NIR fluorescence could accurately identify meningiomas and was correlated with MRI findings and blood-brain barrier permeability. DWIG had high sensitivity and positive predictive value in tumor identification.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
Mihai-Calin Pavel, Mar Achalandabaso Boira, Yasir Bashir, Robert Memba, Erik Llacer, Laia Estalella, Elisabeth Julia, Kevin C. Conlon, Rosa Jorba
Summary: This systematic review aims to evaluate whether near infrared indocyanine green fluorescent cholangiography (NIR-ICG) can visualize extrahepatic biliary anatomy more efficiently and safer than X-ray intraoperative cholangiography (IOC) in minimally invasive cholecystectomy for gallstone disease. The study will include literature search and assessment of randomized controlled clinical trials and prospective non-randomized controlled trials. A meta-analysis will be conducted if the results are sufficiently homogeneous.
SYSTEMATIC REVIEWS
(2022)
Article
Surgery
Ludovica Baldari, Luigi Boni, Hayato Kurihara, Elisa Cassinotti
Summary: The aim of this study was to determine the ideal dose of ICG to achieve optimal visualization of the extra-hepatic biliary tree during laparoscopic cholecystectomy. Using a mathematical function bisection method, a dosage range was identified and the midpoint dose of 0.0119 mg/kg was tested in 50 consecutive surgeries. Results demonstrated that this dosage allowed for ideal intraoperative visualization of the biliary tree.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Chibueze A. Nwaiwu, Vasiliy E. Buharin, Anderson Mach, Robin Grandl, Alyson F. Dechert, Liam J. O'Shea, Steven D. Schwaitzberg, Peter C. W. Kim
Summary: This study aims to investigate the application of laser speckle contrast imaging (LSCI) in real-time surgical visualization of tissue blood flow. By combining with indocyanine green (ICG) fluorescence, LSCI can improve the accuracy and precision of perfusion detection in tissues compared to using ICG alone.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Gijsbert M. Kalisvaart, Ruben P. J. Meijer, Okker D. Bijlstra, Hidde A. Galema, Wobbe O. de Steur, Henk H. Hartgrink, Cornelis Verhoef, Lioe-Fee de Geus-Oei, Dirk J. Grunhagen, Yvonne M. Schrage, Alexander L. Vahrmeijer, Jos A. van der Hage
Summary: This study assessed the potential and limitations of near-infrared fluorescence imaging with indocyanine green in intraoperative tumor identification of GISTs. The results showed that GISTs typically have similar fluorescence intensity to the surrounding tissue, indicating that intraoperatively administered indocyanine green is currently not suitable for adequate tumor identification.
Article
Surgery
P. Van Den Hoven, P. S. Verduijn, L. Van Capelle, F. P. Tange, M. Michi, L. U. M. Corion, B. G. Sibinga Mulder, M. A. M. Mureau, A. L. Vahrmeijer, J. R. Van Der Vorst
Summary: This study utilized ICG NIR fluorescence imaging to analyze perfusion patterns in free flap breast reconstruction, highlighting differences in fluorescence intensity and flow velocity among different regions.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Victor M. Baart, Labrinus van Manen, Shadhvi S. Bhairosingh, Floris A. Vuijk, Luisa Iamele, Hugo de Jonge, Claudia Scotti, Massimo Resnati, Robert A. Cordfunke, Peter J. K. Kuppen, Andrew P. Mazar, Jacobus Burggraaf, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Summary: In this study, fluorescence-guided surgery using uPAR-targeting antibody fragments resulted in earlier tumor visualization compared to the parent IgG, but at the expense of peak fluorescence intensity.
MOLECULAR IMAGING AND BIOLOGY
(2023)
Review
Biology
Marlies Michi, Max Madu, Henri A. H. Winters, Daniel M. de Bruin, Joost R. van der Vorst, Caroline Driessen
Summary: The evidence on bone perfusion measured with near-infrared fluorescence (NIRF) is limited, and more clinical studies are needed to evaluate its clinical significance.
Article
Surgery
Olton S. van Genderen, Rob C. van Wissen, Jaap F. Hamming, Jan van Schaik, Joost R. van der Vorst
Summary: This study aims to describe the concept of aortic elastic deformation (ED) measurement using duplex ultrasonography (DUS) as a tool for detecting high aneurysm sac pressure following endovascular aortic repair (EVAR). The ED can be measured using the dual image function in B-mode of the DUS device and a standardized amount of applied probe pressure. It is hypothesized that less ED of the aneurysm sac can be related to high aneurysm sac pressure and the presence of clinically relevant endoleak.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Review
Surgery
Paul A. Sutton, Martijn A. van Dam, Ronan A. Cahill, Sven Mieog, Karol Polom, Alexander L. Vahrmeijer, Joost van der Vorst
Summary: Fluorescence-guided surgery is an innovative technique that has been widely adopted in various surgical fields. It utilizes near-infrared fluorescence to provide real-time imaging and targeted imaging agents for improved surgical guidance.
Article
Medicine, Research & Experimental
F. P. Tange, P. S. Verduijn, B. G. Sibinga Mulder, L. van Capelle, S. Koning, C. Driessen, M. A. M. Mureau, A. L. Vahrmeijer, J. R. van der Vorst
Summary: This study aims to reduce the occurrence of fat necrosis by using ICG-NIR-FA technology to evaluate the perfusion of DIEP flaps. A total of 280 females undergoing autologous breast reconstruction with DIEP or msTRAM flaps will be randomly assigned to the intervention or control group. The main endpoint of the study is the difference in clinically relevant fat necrosis between the two groups evaluated at two weeks and three months after reconstruction.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2023)
Article
Surgery
Britt W. C. M. Warmerdam, Merieke Stevens, Carla S. P. van Rijswijk, Daniel Eefting, Rutger W. van der Meer, Hein Putter, Jaap F. Hamming, Joost R. van der Vorst, Jan van Schaik
Summary: This retrospective cohort study investigates the learning curve of complex endovascular aortic repair (EVAR) and identifies factors that contribute to successful implementation. The results show a decrease in operating time and length of hospital stay over time, as well as a reduction in cardiac complications. Factors such as communication, trust, shared responsibility and goals, authoritative structures, mutual learning, and team capabilities were found to positively influence the learning curve.
ANNALS OF VASCULAR SURGERY
(2023)
Editorial Material
Surgery
Jeroen Brouwers, Carla van Rijswijk, Pim van den Hoven, Jaap Hamming, Joost R. van der Vorst
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Medicine, General & Internal
Merel Verhagen, Daniel Eefting, Carla van Rijswijk, Rutger van der Meer, Jaap Hamming, Joost van der Vorst, Jan van Schaik
Summary: This study aimed to assess the differences in aortic exclusion between endovascular repair (ER) and open repair (OR) of complex aortic aneurysms. The results showed that ER resulted in longer aortic exclusion and a lower number of patent segmental arteries compared to OR. Therefore, ER and OR should be considered as distinct modalities and require different risk assessments.
JOURNAL OF CLINICAL MEDICINE
(2023)
Editorial Material
Surgery
Joost R. van der Vorst, Martin Teraa
EJVES VASCULAR FORUM
(2023)
Letter
Surgery
Floortje Huizing, Vincent Q. Sier, Jaco A. S. Tresfon, Joost R. Van der Vorst, Ronald S. L. Liem, Roderick F. Schmitz, Abbey Schepers, R. Marijn Houwert, Menno R. Vriens, Heleen S. Snijders, Joris J. Blok
BRITISH JOURNAL OF SURGERY
(2023)
Article
Surgery
Merel J. Verhagen, Marit S. de Vos, Jan van Schaik, Joost R. van der Vorst, Abbey Schepers, Perla J. Marang-van de Mheen, Jaap F. Hamming
BRITISH JOURNAL OF SURGERY
(2023)
Review
Surgery
P. van Den Hoven, J. Osterkamp, N. Nerup, M. B. S. Svendsen, Alexander Vahrmeijer, J. R. van der Vorst, M. P. Achiam
Summary: Incorrect assessment of tissue perfusion carries a significant risk of complications in surgery. The use of near-infrared (NIR) fluorescence imaging with Indocyanine Green (ICG) presents a possible solution. This review provides an overview of quantification methods for perfusion assessment using ICG NIR fluorescence imaging, highlighting the need for standardization of quantification methods in order to improve reliability.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Article
Surgery
Karen van Rijn, Abbey Schepers, Rutger W. van der Meer, Carla S. P. van Rijswijk, Jan van Schaik, Joost R. van der Vorst
Summary: This case report highlights a rare complication of in-stent thrombosis causing high-grade aortic stenosis in a patient with blunt thoracic aortic injury. The patient, who also had concurrent coronavirus disease 2019 infection, was successfully treated with axillofemoral bypass and stent relining. The risk factors and optimal therapeutic approach for in-stent thrombosis remain unknown.
JOURNAL OF VASCULAR SURGERY CASES INNOVATIONS AND TECHNIQUES
(2023)
Article
Surgery
Renu R. Bahadoer, Koen C. M. J. Peeters, Geerard L. Beets, Nuno L. Figueiredo, Esther Bastiaannet, Alexander Vahrmeijer, Sofieke J. D. Temmink, W. M. Elma Meershoek-Klein Kranenbarg, Annet G. H. Roodvoets, Angelita Habr-Gama, Rodrigo O. Perez, Cornelis J. H. van de Velde, Denise E. Hilling
Summary: This study compared the oncological outcomes of watch and wait strategy in rectal cancer patients aged less than 50 years with those aged 50 years or more. The study found no additional oncological risk in young patients compared with their older counterparts when following a watch-and-wait strategy after a clinical complete response.
BRITISH JOURNAL OF SURGERY
(2022)