4.6 Article

Laparoscopic rectal resection for severe endometriosis of the mid and low rectum: technique and operative results

期刊

出版社

SPRINGER
DOI: 10.1007/s00464-011-1991-8

关键词

Endometriosis; Rectum; Laparoscopy; Resection; Anastomotic leak; Complications

类别

向作者/读者索取更多资源

Background Although several studies have shown that laparoscopic resection is safe and feasible in bowel endometriosis, limited data are available on the specific treatment for endometriosis of the rectum. The aim of this study is to describe operative and postoperative outcomes after laparoscopic resection of the mid/low rectum for endometriosis. Methods Between 2002 and 2010, 750 patients (median age 33 years) underwent laparoscopic resection of the mid/low rectum for deep infiltrating endometriosis at a single institution. All operations were performed with a standardized technique by a single surgeon. Results Median operative time was 255 min, and median blood loss 150 ml. Of patients, 7% required blood transfusions. Laparotomic conversion rate was 1.6%. Mechanical low and very low colorectal anastomoses were carried out in 92.5 and 7.5% of patients, respectively. Temporary ileostomy rate was 14.5%. Median length of stay was 8 days. Overall surgical morbidity was 9% with no mortality. Rates of anastomotic leak, rectovaginal fistula, and intraabdominal bleeding were 3, 2, and 1.2%. Forty patients (5.5%) required reoperation. Conclusions Laparoscopic resection of the mid/low rectum for endometriosis can be performed safely with acceptable rates of morbidity/reoperation and with low rates of specific complications, including anastomotic leak and rectovaginal fistula. The very high surgical volume of the operating surgeon is probably one of the most important factors in order to maximize postoperative outcomes.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Surgery

Total Pancreatectomy With Islet Autotransplantation as an Alternative to High-risk Pancreatojejunostomy After Pancreaticoduodenectomy A Prospective Randomized Trial

Gianpaolo Balzano, Alessandro Zerbi, Francesca Aleotti, Giovanni Capretti, Raffella Melzi, Nicolo Pecorelli, Alessia Mercalli, Rita Nano, Paola Magistretti, Francesca Gavazzi, Francesco De Cobelli, Dario Poretti, Marina Scavini, Chiara Molinari, Stefano Partelli, Stefano Crippa, Paola Maffi, Massimo Falconi, Lorenzo Piemonti

Summary: This study compared pancreaticoduodenectomy (PD) and total pancreatectomy (TP) with islet autotransplantation (IAT) in high-risk patients for postoperative pancreatic fistula (POPF). The results showed that although PD had a higher incidence of complications, TP-IAT had a shorter postoperative stay and patients had good metabolic control and sustained C-peptide production.

ANNALS OF SURGERY (2023)

Article Surgery

Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis Tumor Biology Cuts the Deal

Dilmurodjon Eshmuminov, Debora J. Studer, Victor Lopez Lopez, Marcel A. Schneider, Jan Lerut, Mary Lo, Linda Sher, Thomas J. Musholt, Oana Lozan, Nabila Bouzakri, Carlo Sposito, Rosalba Miceli, Shoma Barat, David Morris, Helga Oehler, Teresa Schreckenbach, Peri Husen, Charles B. Rosen, Gregory J. Gores, Toshihiko Masui, Tan-To Cheung, Corina Kim-Fuchs, Aurel Perren, Philipp Dutkowski, Henrik Petrowsky, Espen Thiis-Evensen, Pal-Dag Line, Michal Grat, Stefano Partelli, Massimo Falconi, Lulu Tanno, Ricardo Robles-Campos, Vincenzo Mazzaferro, Pierre-Alain Clavien, Kuno Lehmann

Summary: This multicenter study compares the outcomes of liver resection (LR) and liver transplantation (LT) in patients with neuroendocrine liver metastasis (NELM). The results suggest that LT provides a survival benefit over LR, but adherence to selection criteria is important.

ANNALS OF SURGERY (2023)

Review Surgery

Advantages of laparoscopic distal pancreatectomy: Systematic review and meta-analysis of randomized and matched studies

Alessandro Cucchetti, Antonio Bocchino, Stefano Crippa, Leonardo Solaini, Stefano Partelli, Massimo Falconi, Giorgio Ercolani

Summary: This meta-analysis and credibility assessment compared laparoscopic distal pancreatectomy with open distal pancreatectomy in terms of early and oncologic outcomes. The results showed that laparoscopic distal pancreatectomy was superior to open distal pancreatectomy in terms of early outcomes, including decreased postoperative stay and blood loss. However, the oncologic outcomes were inconclusive, with higher R0 resection rate and shorter time to adjuvant therapy seen in laparoscopic distal pancreatectomy, but no confirmed survival benefit at 3 years.

SURGERY (2023)

Article Surgery

Development of a predictive model for unplanned intensive care unit admission after pancreatic resection within an enhanced recovery pathway

Nicolo Pecorelli, Stefano Turi, Maria Teresa Salvioni, Giovanni Guarneri, Pietro Barbieri, Alessia Vallorani, Domenico Tamburrino, Stefano Crippa, Stefano Partelli, Luigi Beretta, Massimo Falconi

Summary: This study aimed to determine the predictors of unplanned ICU admission in patients undergoing pancreatectomy and compare outcomes between direct and late ICU admission. The study found that patient comorbidities, surgical complexity, and lactic acidosis at the end of surgery were associated with unplanned postoperative ICU admission. Late ICU admission had higher mortality rates compared to direct admission.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2023)

Article Surgery

Management of clinically relevant postoperative pancreatic fistula-related fluid collections after distal pancreatectomy

Giovanni Guarneri, Giorgia Guazzarotti, Nicolo Pecorelli, Diego Palumbo, Marco Palucci, Lorenzo Provinciali, Chiara Limongi, Stefano Crippa, Stefano Partelli, Francesco De Cobelli, Massimo Falconi

Summary: This study analyzed clinically relevant postoperative pancreatic fistula (CR-POPF) cases related to distal pancreatectomy and identified factors associated with the need for invasive procedures. The results showed that the occurrence rate of CR-POPF within 90 days after surgery was 40.1%, with 25.2% of patients experiencing symptomatic fluid collections related to fistula. Increased body mass index and intraoperative blood loss were associated with fluid collections, while CT scan parameters were associated with the need for invasive procedures.

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES (2023)

Article Gastroenterology & Hepatology

Endoscopic papillectomy for ampullary lesions in patients with familial adenomatous polyposis compared with sporadic lesions: a propensity score-matched cohort

Kien Vu Trung, Einas Abou-Ali, Fabrice H. Caillol, Woo Paik, Bertrand Napoleon, Viliam E. Masaryk, Sophia van der Wiel, Enrique Perez-Cuadrado-Robles, Nicolas Musquer, Asif Halimi, Kevin R. Soares, Francois Souche, Steffen C. Seyfried, Maria Petrone, Stefano Crippa, Tobias Kleemann, David J. Albers, Tobias Weismueller, Ana Dugic, Benjamin Meier, Edris Wedi, Moritz Schiemer, Sara Regner, Sebastien Gaujoux, Marcus Hollenbach, Francesco Auriemma, Aiste Gulla, Elias Karam, Marc Giovannini, Jean-Philippe Ratone, Uwe Will, Rita Saadeh, Marco J. Bruno, Pierre Deprez, Urban Arnelo, Erik Haraldsson, Alexander Waldthaler, Galen Leung, Mark A. Schattner, William R. Jarnagin, Tiegong Wang, Jean M. Fabre, Georg Kaehler, Alberto Mariani, Piera Zaccari, Giulio Belfiori, Massimo Falconi, Stefano Partelli, Alessandro Repici, Andrea Anderloni, Johanna Laukkarinen, Albrecht Hoffmeister, Jonas Rosendahl, Brigitte Schumacher, Louise Barbier, Dominik Heling, Steffen Muehldorfer, Stephanie Truant, Karel Caca, Marcel Tantau, Katrin Salzmann, Patrice David, Arthur Schmidt, Tullio Piardi, J. Matthias Loehr, Johan Gagniere, Bogdan P. Miutescu, Arthur Berger, Peter Schemmer, Christian Heise, Vasile Sandru, Reea Ahola, Mario Dinis-Ribeiro, Tiago Curdia Goncalves, Doerte Wichmann

Summary: This study retrospectively analyzed the outcomes of endoscopic papillectomy in FAP-related and sporadic ampullary lesions. The study found that endoscopic papillectomy is safe and effective for FAP-related ampullary lesions, and FAP patients require long-term surveillance.

ENDOSCOPY (2023)

Article Radiology, Nuclear Medicine & Medical Imaging

Somatostatin receptor activity assessed by 68Ga-DOTATOC PET can preoperatively predict DAXX/ATRX loss of expression in well-differentiated pancreatic neuroendocrine tumors

Paola Mapelli, Carolina Bezzi, Francesca Muffatti, Samuele Ghezzo, Francesco Baldassi, Marco Schiavo Lena, Valentina Andreasi, Carla Canevari, Patrizia Magnani, Francesco De Cobelli, Luigi Gianolli, Stefano Partelli, Massimo Falconi, Maria Picchio

Summary: The study aims to evaluate the role of Ga-68-DOTATOC PET parameters in predicting the loss of DAXX/ATRX expression in patients with Pancreatic neuroendocrine tumors (PanNET) candidate to surgery. The results showed that SRD and TLSRD could predict the loss of DAXX expression. When evaluating SRD in combination with radiological diameter, only SRD maintained statistical significance.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2023)

Article Surgery

Regret affects the choice between neoadjuvant therapy and upfront surgery for potentially resectable pancreatic cancer

Alessandro Cucchetti, Benjamin Djulbegovic, Stefano Crippa, Iztok Hozo, Monica Sbrancia, Athanasios Tsalatsanis, Cecilia Binda, Carlo Fabbri, Roberto Salvia, Massimo Falconi, Giorgio Ercolani

Summary: A regret-based decision model was applied to evaluate attitudes toward neoadjuvant therapy versus upfront surgery for potentially resectable pancreatic adenocarcinoma. Results showed that regret of omission and commission influenced clinicians' therapeutic decisions, and surgeons or specialists working in surgical centers were less likely to recommend neoadjuvant therapy.

SURGERY (2023)

Review Oncology

Clinical Prediction Models for Recurrence in Patients with Resectable Grade 1 and 2 Sporadic Non-Functional Pancreatic Neuroendocrine Tumors: A Systematic Review

Jeffrey W. Chen, Charlotte M. Heidsma, Anton F. Engelsman, Ertunc Kabaktepe, Susan van Dieren, Massimo Falconi, Marc G. Besselink, Els J. M. Nieveen van Dijkum

Summary: The risk prediction for tumor recurrence after surgery for non-functional pancreatic neuroendocrine tumors is a major unmet clinical need. Multiple prediction models have been developed, but none are currently incorporated into international guidelines. This systematic review found 13 original models, of which 3 were validated outside the patient group in which they were developed. The lack of external validation hinders the progress toward clinical use.

CANCERS (2023)

Article Oncology

Geographical Disparities and Patients' Mobility: A Plea for Regionalization of Pancreatic Surgery in Italy

Gianpaolo Balzano, Giovanni Guarneri, Nicolo Pecorelli, Stefano Partelli, Stefano Crippa, Augusto Vico, Massimo Falconi, Giovanni Baglio

Summary: This study highlights the significant disparities in access to pancreatic surgery in Italy. The distribution of adequate facilities for pancreatic surgery is uneven across the country, with patients from the south and central regions having higher rates of mobility to the north for surgery. The study also found that mortality rates were higher for non-migrating patients in the south and central regions, indicating the need for improved facilities and equal access to care.

CANCERS (2023)

Article Gastroenterology & Hepatology

European' health care indicators and pancreatic cancer incidence and mortality: A mediation analysis of Eurostat data and Global Burden of Disease Study 2019

Alessandro Cucchetti, Philip Johnson, Gabriele Capurso, Stefano Crippa, Carlo Alberto Pacilio, Carlo Fabbri, Massimo Falconi, Giorgio Ercolani

Summary: The aim of this study was to explore the correlation between incidence and mortality of pancreatic cancer and healthcare indicators in 36 European countries. The results showed that both incidence and mortality were increasing, and they were strongly positively correlated. Higher health expenditure, availability of beds and medical technology, as well as the number of practicing doctors were related to higher incidence. On the other hand, lower mortality was associated with indicators such as outpatient curative care expenditure, the number of pet scanners, and radiation therapy equipment. The study highlights the impact of healthcare environment on pancreatic cancer incidence and mortality.

PANCREATOLOGY (2023)

Article Oncology

Immunomodulatory Effects of Endoscopic Ultrasound-Guided Thermal Ablation in Patients with Pancreatic Ductal Adenocarcinoma

Sabrina Gloria Giulia Testoni, Claudia Minici, Elisa Benetti, Francesca Clemente, Daniela Boselli, Clara Sciorati, Lucia De Monte, Maria Chiara Petrone, Markus Enderle, Walter Linzenbold, Maria Pia Protti, Angelo Manfredi, Francesco De Cobelli, Michele Reni, Massimo Falconi, Gabriele Capurso, Paolo Giorgio Arcidiacono, Emanuel Della-Torre

Summary: Thermal ablation under endoscopic ultrasound (EUS)-guidance has shown potential to enhance immune response in pancreatic ductal adenocarcinoma (PDAC). In a recent trial, EUS-guided ablation with HybridTherm Probe (HTP) in combination with chemotherapy improved disease progression compared to chemotherapy alone. This study explored the effects of EUS-HTP on systemic immune response in PDAC and found that it selectively affected immunological predictors of poor outcome.

CANCERS (2023)

Meeting Abstract Urology & Nephrology

DECIPHERING THE RELATIONSHIP BETWEEN PATHOGENIC VARIANTS AND CLINICAL PHENOTYPE IN VHL PATIENTS: RESULTS FROM A PROSPECTIVE OBSERVATIONAL STUDY

Chiara Re, Federico Belladelli, Francesco Cei, Lucia Salerno, Sara Cusano, Floriana Iannace, Giovanni Battista Pipitone, Paola Carrera, Annalisa Russo Raucci, Maria Grazia Patricelli, Andrea Falini, Francesco De Cobelli, Pietro Mortini, Francesco Bandello, Rosangela Lattanzio, Massimo Falconi, Stefano Partelli, Andrea Necchi, Laura Marandino, Irene Franco, Isaline Rowe, Francesco Montorsi, Umberto Capitanio, Alessandro Larcher, Andrea Salonia

JOURNAL OF UROLOGY (2023)

Meeting Abstract Urology & Nephrology

GENERALIZABILITY OF THE MK-6482-004 TRIAL TO REAL-WORLD VHL PATIENTS: RESULTS FROM A PROSPECTIVE SURVEILLANCE STUDY

Federico Belladelli, Chiara Re, Francesco Cei, Lucia Salerno, Sara Cusano, Floriana Iannace, Paola Carrera, Maria Grazia Patricelli, Andrea Falini, Francesco De Cobelli, Pietro Mortini, Francesco Bandello, Rosangela Lattanzio, Massimo Falconi, Stefano Partelli, Andrea Necchi, Daniele Raggi, Laura Marandino, Roberta Luciano, Isaline Rowe, Irene Franco, Francesco Montorsi, Umberto Capitanio, Alessandro Larcher, Andrea Salonia

JOURNAL OF UROLOGY (2023)

Article Surgery

Preoperative CT image analysis to improve risk stratification for clinically relevant pancreatic fistula after distal pancreatectomy

Nicolo Pecorelli, Diego Palumbo, Giovanni Guarneri, Chiara Gritti, Francesco Prato, Marco Schiavo Lena, Alessia Vallorani, Stefano Partelli, Stefano Crippa, Claudio Doglioni, Francesco De Cobelli, Massimo Falconi

BRITISH JOURNAL OF SURGERY (2023)

暂无数据