Article
Oncology
Magdalena Zaborowska-Szmit, Marta Olszyna-Serementa, Dariusz M. Kowalski, Sebastian Szmit, Maciej Krzakowski
Summary: The combination of chemotherapy and radiotherapy is more beneficial in elderly patients with locally advanced unresectable non-small-cell lung cancer compared to radiotherapy alone. Sequential chemoradiotherapy may result in more complete response and less distant metastases in older patients, leading to significantly longer survival.
Article
Surgery
Osamu Yoshino, Yifan Wang, Frances McCarron, Benjamin Motz, Huaping Wang, Erin Baker, David Iannitti, John B. B. Martinie, Dionisios Vrochides
Summary: Robotic surgery is not commonly used for hepato-pancreato-biliary procedures, but we hypothesized that it would be beneficial for elderly patients undergoing major hepatectomy. Our study found that robotic hepatectomy had advantages over laparoscopic hepatectomy in terms of shorter hospital and ICU stays, potentially overcoming the perceived financial burden.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Critical Care Medicine
Jan Gunst, Astrid De Bruyn, Michael P. Casaer, Sarah Vander Perre, Lies Langouche, Greet Van den Berghe
Summary: The study found that tight glucose control in critically ill patients receiving early parenteral nutrition did not increase circulating 3-hydroxybutyrate concentrations, indicating that the protective effects cannot be attributed to increased ketone body availability.
Article
Surgery
Jessica Y. Liu, Sebastian D. Perez, Glen G. Balch, Patrick S. Sullivan, Jahnavi K. Srinivasan, Charles A. Staley, John Sweeney, Jyotirmay Sharma, Virginia O. Shaffer
Summary: The study compared elderly and younger patients undergoing surgery with ERAS protocols and found that elderly patients had similar or better outcomes in terms of readmission rates, bowel function recovery, and diet tolerance. This suggests that ERAS protocols are also beneficial for elderly patients undergoing surgery.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Oncology
I-Shiow Jan, Hui Ju Ch'ang
Summary: The role of radiotherapy in the treatment of pancreatic adenocarcinoma is still uncertain, although some studies have shown improved locoregional control with no survival benefit. By studying various biomarkers, patients who may benefit the most from local radiotherapy can be identified.
RADIATION ONCOLOGY
(2023)
Article
Medicine, General & Internal
Hyung Park, Thaddeus Tarpey, Mengling Liu, Keith Goldfeld, Yinxiang Wu, Danni Wu, Yi Li, Jinchun Zhang, Dipyaman Ganguly, Yogiraj Ray, Shekhar Ranjan Paul, Prasun Bhattacharya, Artur Belov, Yin Huang, Carlos Villa, Richard Forshee, Nicole C. Verdun, Hyun Ah Yoon, Anup Agarwal, Ventura Alejandro Simonovich, Paula Scibona, Leandro Burgos Pratx, Waldo Belloso, Cristina Avendano-Sola, Katharine J. Bar, Rafael F. Duarte, Priscilla Y. Hsue, Anne F. Luetkemeyer, Geert Meyfroidt, Andre M. Nicola, Aparna Mukherjee, Mila B. Ortigoza, Liise-anne Pirofski, Bart J. A. Rijnders, Andrea Troxel, Elliott M. Antman, Eva Petkova
Summary: This study aimed to develop an index for predicting the relative treatment benefit from COVID-19 convalescent plasma (CCP) compared to treatment without CCP. The study found that CCP treatment may be most effective for patients with preexisting conditions and those in the early stages of COVID-19.
Article
Computer Science, Interdisciplinary Applications
M. van den Boorn, V Lagerburg, S. C. J. van Steen, R. Wedzinga, R. J. Bosman, P. H. J. van der Voort
Summary: The aim of the study was to develop a glucose prediction model applicable for all ICU patients with an expected stay of at least 24 hours. The model, based on historical glucose data, showed promising accuracy in predicting glucose levels 30 minutes ahead, marking a significant step in the development of a closed-loop glucose system.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Oncology
Jianping Guo, Zhizhong Xiong, Shi Yin, Yue'e Wen, Longyang Jin, Caiqin Wang, Huaxian Chen, Dandong Luo, Zijian Deng, Dayin Huang, Xianzhe Li, Biying Yi, Chaobin Mao, Lei Lian
Summary: This study identified 75 years old as the optimal age cutoff for defining EGC, and found that EGC patients had significantly worse overall survival and cancer-specific survival compared to non-EGC group. Adjuvant chemotherapy was proved to be unbeneficial for stage II EGC patients.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Psychology, Multidisciplinary
Xiao J. Liu, Sha Ge, Alberto Cordova, Zayd Yaghi, Bo Y. Jiang, Guang H. Yue, Wan X. Yao
Summary: The objective of this study was to determine the effectiveness of mental imagery training (MIT) on enhancing maximum voluntary muscle contraction (MVC) force in healthy young and old adults. The results showed that MIT had a significant effect on enhancing muscle strength compared to no exercise, but was inferior to physical training (PT). Subgroup analysis further indicated that MIT was more effective for older adults and small finger muscles.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Oncology
Jens Mittler, Stefan Heinrich, Martina Koch, Maria Hoppe-Lotichius, Ali Hadian, Arndt Weinmann, Roman Kloeckner, Peter Robert. Galle, Hauke Lang
Summary: In a study of nearly 100 elderly patients undergoing LT for cirrhosis-associated hepatocellular carcinoma, it was found that patients aged 65 and older can benefit from LT, with outcomes comparable to younger patients.
Article
Horticulture
Anna Diveky-Ertsey, Marta Ladanyi, Barbara Biro, Monika Mate, Dora Drexler, Ferenc Toth, Krisztina Bozine Pullai, Attila Gere, Peter Pusztai, Laszlo Csambalik
Summary: This study investigates the impact of open-field vs. protected production on various bioactive compound parameters and antioxidant status of tomato PGRs. The analysis reveals that the phytonutrient content of certain PGRs is influenced more by microclimatic conditions than production location. Additionally, different PGRs perform differently in different production systems. These findings enrich the nutritional datasets of tomato landraces and have important implications for the conservation and utilization of PGRs in breeding programs.
Article
Nutrition & Dietetics
Liyin Zhang, Keyu Guo, Qi Tian, Jianan Ye, Zhiyi Ding, Qin Zhou, Xia Li, Zhiguang Zhou, Lin Yang
Summary: Despite comparable clinical indicators, glycemic variability (GV) in some patients with type 1 diabetes (T1D) remains heterogeneous, and the underlying factors are unknown. Metabolomic analysis revealed significant differences in 25 metabolites between high GV and low GV groups, with spermidine, L-methionine, and trehalose showing consistent differences in both exploratory and validation sets. These findings suggest that metabolomic disturbances may impact the GV of T1D patients.
Article
Endocrinology & Metabolism
Raoul Orvieto, Adva Aizer, Bozhena Saar-Ryss, Lilach Marom-Haham, Meirav Noach-Hirsh, Jigal Haas, Ravit Nahum
Summary: For patients undergoing elective egg freezing, ovarian stimulation with high daily gonadotropin doses is recommended to maximize the oocyte yield. In the second IVF cycle attempt, patients who had a high response in the first attempt may have a reduced oocyte yield regardless of the daily gonadotropin dose. Additionally, patients with high peak E2 levels in the first attempt and a basal Day-3 FSH/LH ratio < 1.5 and/or more than 9 retrieved oocytes should continue with the same ovarian stimulation protocol without changing the daily gonadotropin dose.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Gastroenterology & Hepatology
Bin Xu, Jinbo Shi, Wenjie Lu, Yulian Wu, Xin Dong
Summary: This study investigates the benefits of postoperative chemotherapy for elderly patients with resectable pancreatic ductal adenocarcinoma (PDAC). It finds that elderly patients have poorer prognosis compared to younger patients, but postoperative chemotherapy can prolong overall survival in the elderly group similarly to the younger group.
Article
Oncology
Chao Zhou, Liqiao Hou, Xingni Tang, Changxing Liu, Yinnan Meng, Haijian Jia, Haihua Yang, Suna Zhou
Summary: This study investigated the application of a CT stimulation-based radiomics model for screening patients with locally advanced non-small cell lung cancer (NSCLC) who can benefit from adaptive radiotherapy (ART). The results showed that the model could effectively predict the efficacy of ART, and ART had significant benefits in the lung, heart, cord, and esophagus. This study provides guidance and promotes the application of ART in the clinic.
RADIOTHERAPY AND ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Raymond Laird, Fred Brody, Jeffrey N. Harr, Nathan G. Richards, Steve Zeddun
JOURNAL OF GASTROINTESTINAL SURGERY
(2015)
Article
Surgery
Theresa L. Chin, Ernest E. Moore, Marilyn E. Coors, James G. Chandler, Arsen Ghasabyan, Jeffrey N. Harr, John R. Stringham, Christopher R. Ramos, Sarah Ammons, Anirban Banerjee, Angela Sauaia
Article
Critical Care Medicine
Jeffrey N. Harr, Ernest E. Moore, Jeffrey Johnson, Theresa L. Chin, Max V. Wohlauer, Ronald Maier, Joseph Cuschieri, Jason Sperry, Anirban Banerjee, Christopher C. Silliman, Angela Sauaia
CRITICAL CARE MEDICINE
(2013)
Article
Emergency Medicine
J. N. Harr, E. E. Moore, T. L. Chin, M. P. Chapman, A. Ghasabyan, J. R. Stringham, A. Banerjee, C. C. Silliman
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2015)
Meeting Abstract
Surgery
John R. Stringham, Ernest E. Moore, Fabia Gamboni, Miguel Fragoso, Theresa L. Chin, Jeffrey N. Harr, Christopher C. Silliman, Anirban Banerjee
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2013)
Article
Critical Care Medicine
Michael P. Chapman, Ernest E. Moore, Christopher R. Ramos, Arsen Ghasabyan, Jeffrey N. Harr, Theresa L. Chin, John R. Stringham, Angela Sauaia, Christopher C. Silliman, Anirban Banerjee
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2013)
Article
Critical Care Medicine
Jeffrey N. Harr, Ernest E. Moore, Theresa L. Chin, Arsen Ghasabyan, Eduardo Gonzalez, Max V. Wohlauer, Anirban Banerjee, Christopher C. Silliman, Angela Sauaia
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2013)
Article
Critical Care Medicine
John R. Stringham, Ernest E. Moore, Fabia Gamboni, Jeffrey N. Harr, Miguel Fragoso, Theresa L. Chin, Caitlin E. Carr, Christopher C. Silliman, Anirban Banerjee
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2014)
Article
Critical Care Medicine
Jeffrey N. Harr, Ernest E. Moore, Arsen Ghasabyan, Theresa L. Chin, Angela Sauaia, Anirban Banerjee, Christopher C. Silliman
Article
Critical Care Medicine
Anirban Banerjee, Ernest E. Moore, Nathan J. McLaughlin, Luis Lee, Wilbert L. Jones, Jeffrey L. Johnson, Trevor L. Nydam, Christopher C. Silliman
Article
Critical Care Medicine
Jeffrey N. Harr, Ernest E. Moore, Theresa L. Chin, Arsen Ghasabyan, Eduardo Gonzalez, Max V. Wohlauer, Angela Sauaia, Anirban Banerjee, Christopher C. Silliman
Article
Critical Care Medicine
Ernest E. Moore, Theresa L. Chin, Michael C. Chapman, Eduardo Gonzalez, Hunter B. Moore, Christopher C. Silliman, Kirk C. Hansen, Angela Sauaia, Anirban Banerjee
Article
Surgery
Jeffrey N. Harr, Ivy N. Haskins, Richard L. Amdur, Samir Agarwal, Vincent Obias
JOURNAL OF ROBOTIC SURGERY
(2018)