Article
Environmental Sciences
M. Ramya, P. Senthil Kumar, Gayathri Rangasamy, V. Uma Shankar, G. Rajesh, K. Nirmala
Summary: An electrochemical sensor using a copper oxide Molybdenum sulfide modified electrode was employed for the detection of sulfamethoxazole. The CuO/MoS2 modified electrode exhibited exceptional electrochemical performance, showing enhanced conductivity and linear correlation between peak current and SMX concentration, with a reliable detection limit of 0.3 mu M.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Analytical
Ghadeer A. R. Y. Suaifan, Mohammad F. Khanfar, Mayadah B. Shehadeh, Asmaa Alnajajrah, Raghad Abuhamdan, Sameer Ahmad Hasan
Summary: This study successfully developed an electroanalytical electrode for the detection of albendazole (ABZ) active ingredient in pharmaceutical dosage form and contaminated animal-derived products. The modified electrode demonstrated high sensitivity and applicability, making it suitable for quality control in the pharmaceutical and food industry.
Article
Chemistry, Analytical
Tugba Tabanligil Calam, Elif Begum Yilmaz
Summary: A new voltammetric method was developed for the determination of 8-hydroxyquinoline using an ANSA-GC modified electrode, showing excellent stability and reproducibility. The modified electrode was successfully applied for the determination of 8-hydroxyquinoline in a blush cosmetic product with results comparable to standard spectrophotometry.
INSTRUMENTATION SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jose Rodrigo Quejigo, Benjamin Korth, Anne Kuchenbuch, Falk Harnisch
Summary: The study investigates the distribution of Geobacter spp. and their electrochemical performance within exemplary fixed-bed electrodes. Results show that approximately 10% of the bed volume, specifically near the current collector, achieves the majority of electroactivity. Despite Geobacter spp. dominating all sampled granules, engineered bed electrodes are needed to improve electron exchange between microorganisms and granules.
Article
Chemistry, Analytical
Fikret Ari, Bahar Ince, Mehmet Altay Unal, Mustafa Kemal Sezginturk, Sibel A. Ozkan
Summary: Although there is still room for improvement in diagnostic and treatment options for various cancers, electrochemical biosensors using quartz tuning forks (QTF) have emerged as a promising platform. This research explores the functionalization and isolation of QTF for biomarker determination, demonstrating their unique response and sensitivity. The results show that QTF-based immunosensors have high detection sensitivity and low cost, making them ideal for point-of-care diagnostic devices.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Sutthima Sriprasertsuk, Simone C. Mathias, John R. Varcoe, Carol Crean
Summary: PPy.SDS-coated carbon fiber electrodes demonstrated enhanced drug sensing capabilities compared to bare carbon fibers, with a 14-fold increase in electrochemical surface area. The use of a large counter anion as dopant, such as dodecyl sulfate, resulted in a greater drug sensing response. Differential pulse voltammetry (DPV) with PPy.SDS fiber electrodes was able to detect paracetamol with a detection limit of 34 μM and a linear response range of 50-500 μM, even in the presence of interferents like dopamine and ascorbic acid at 100 μM concentrations. This indicates the potential for real-world applications of PPy.SDS electrodes in drug sensing, with the ability to detect anti-psychotic medication like clozapine at low concentrations.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Fabian M. Schuett, Sven J. Zeller, Maximilian J. Eckl, Felix M. Matzik, Maren-Kathrin Heubach, Tanja Geng, Johannes M. Hermann, Matthias Uhl, Ludwig A. Kibler, Albert K. Engstfeld, Timo Jacob
Summary: A simple method for fabricating stable 3D-printed micro-reference electrodes using polyvinylidene fluoride is proposed in this study, showing good chemical inertness in strong acids, bases, and non-aqueous solvents. Experimental results demonstrate the versatility and stability of this new class of micro-reference electrodes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Electrochemistry
Anna Kwiecien, Adam Sroka, Irena Majerz
Summary: A new electrochemical method was developed for the determination of fenamic acid and its derivatives in aqueous solution, showing advantages of convenience, speed, and low cost. The study suggests potential applications of the proposed electrochemical method in the pharmaceutical industry, with detailed research and determination of various analytical parameters.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Longwen Lei, Yuxin Pan, Yanjie Dong
Summary: An ethylenediamine perovskite material C2H4(NH3)(2)Pb2Br6NCs was designed and synthesized, and used to modify glassy carbon electrodes in the form of C2H4(NH3)(2)Pb2Br6NCs and C2H4(NH3)(2)Pb2Br6NCs/graphene oxide composite materials. The cyclic voltammetry method was employed to determine metal ions, showing good sensitivity and selectivity towards Ag+ and Hg2+. Optimal experimental conditions were determined through investigation of various control factors. This method was successfully applied to the determination of Ag+ concentration in wastewater samples from Tongling Nonferrous Metals Factory and Hg2+ concentration in water from Anqing Shitang Lake, with high recovery rates and consistent results with inductively coupled plasma emission spectrometer measurement.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Dalia L. Swinya, Daniel Martin-Yerga, Marc Walker, Patrick R. Unwin
Summary: The adsorption and electron-transfer kinetics of dopamine on carbon electrodes were investigated in this study. It was found that anodization of glassy carbon electrodes improves the electron-transfer kinetics and provides more adsorption sites for dopamine. However, adsorption takes longer to reach completion on the anodized surface and the extent of adsorption is less compared to the unmodified surface. Additionally, lower graphitic and higher oxygen content on the anodized electrodes suggest that oxygen-containing functional groups may not enhance dopamine adsorption.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Physical
Dalia L. Swinya, Daniel Martin-Yerga, Marc Walker, Patrick R. Unwin
Summary: This study investigated the adsorption and electrochemical behavior of dopamine (DA) on carbon electrodes with different structures and compositions using scanning electrochemical cell microscopy (SECCM). The results showed that anodization can enhance the electron-transfer kinetics and adsorption sites of DA, but adsorption takes longer on the anodized surface. In addition, the electrochemical surface area (ECSA) is an important consideration for calculating the surface coverage of DA, and anodization reduces the surface coverage. Lower graphitic and higher oxygen content on anodized carbon electrodes suggest that oxygen-containing functional groups do not necessarily enhance the adsorption of DA.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Inorganic & Nuclear
Rukaya Banu, B. E. Kumara Swamy, Eno Ebenso
Summary: This study presents a simplified and efficient method for quantifying serotonin and epinephrine using a customised glassy carbon electrode. The developed sensor effectively accelerates the electrocatalytic current response and shows good selectivity and sensitivity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Mohamed Abd-Elsabour, Abdulrahman G. Alhamzani, Mortaga M. Abou-Krisha
Summary: This article investigates the electrochemical oxidation of methanol at various nickel-modified electrodes in NaOH solution, and finds that the newly developed poly-p-PD/Ni(II)/GE electrode exhibits higher catalytic activity for methanol oxidation. The electrochemical activity and diffusion-controlled process at the surface of the poly-p-PD/Ni(II)/GE electrode are also analyzed.
Article
Electrochemistry
Mohammed A. Kassem, Wejdan M. Al-Zahrani, Zahrah T. Althagafi, Gharam I. Mohammed, Mohamed I. Awad
Summary: Electrochemical oxidation of a glassy carbon electrode enables the detection of flutamide. The oxidation process is simple and efficient, and involves applying a potential to the electrode. Optimized experimental parameters led to a linear relationship between the electrode response and the concentration of flutamide, with a relative standard deviation of 4.2%.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2022)
Article
Chemistry, Analytical
Lawrence K. Muthuri, Livia Nagy, Geza Nagy
Summary: Recently, a novel chronopotentiometric method has been introduced for assessing antioxidant activity. The performance of chemically modified working electrodes made of different pencil materials were tested in this method. The stability and structure of the formed Meldola Blue film on the electrode surfaces were studied. Antioxidant measurements were conducted by controlled potential oxidation of the mediator and recording the open cell potential over time. The initial slope of the recorded potential was used as the analytical signal, showing the applicability of the pencil probes.
Review
Materials Science, Multidisciplinary
Stefania Cometa, Maria Addolorata Bonifacio, Monica Mattioli-Belmonte, Luigia Sabbatini, Elvira De Giglio
Article
Materials Science, Ceramics
Francesca Tana, Elvira De Giglio, Stefania Cometa, Agnese D'Agostino, Andrea Serafini, Fabio Variola, Nina Bono, Roberto Chiesa, Luigi De Nardo
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2020)
Article
Materials Science, Biomaterials
Stefania R. Cicco, Danilo Vona, Gabriella Leone, Elvira De Giglio, Maria A. Bonifacio, Stefania Cometa, Saverio Fiore, Fabio Palumbo, Roberta Ragni, Gianluca M. Farinola
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Materials Science, Biomaterials
Maria A. Bonifacio, Andrea Cochis, Stefania Cometa, Annachiara Scalzone, Piergiorgio Gentile, Giuseppe Procino, Serena Milano, Alessandro C. Scalia, Lia Rimondini, Eivira De Giglio
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Review
Chemistry, Physical
Stefania Cometa, Maria A. Bonifacio, Ana M. Ferreira, Piergiorgio Gentile, Elvira De Giglio
Article
Chemistry, Analytical
Stefania Cometa, Maria Addolorata Bonifacio, Giuseppe Trapani, Sante Di Gioia, Laura Dazzi, Elvira De Giglio, Adriana Trapani
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2020)
Article
Biotechnology & Applied Microbiology
Annachiara Scalzone, Maria A. Bonifacio, Stefania Cometa, Fabio Cucinotta, Elvira De Giglio, Ana M. Ferreira, Piergiorgio Gentile
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Maria A. Bonifacio, Giorgia Cerqueni, Stefania Cometa, Caterina Licini, Luigia Sabbatini, Monica Mattioli-Belmonte, Elvira De Giglio
Article
Biochemistry & Molecular Biology
Loris Pinto, Maria Addolorata Bonifacio, Elvira De Giglio, Stefania Cometa, Antonio F. Logrieco, Federico Baruzzi
Article
Polymer Science
Stefania Cometa, Maria Addolorata Bonifacio, Elisabetta Tranquillo, Antonio Gloria, Marco Domingos, Elvira De Giglio
Summary: Additive manufacturing (AM) is revolutionizing the clinical treatment of bone diseases by allowing for the fabrication of customized, complex 3D structures with bioactive materials. Among various AM techniques, BioCell Printing stands out as an advanced system for manufacturing materials and promoting cell growth, offering new possibilities for creating high-resolution micro-architectures.
Editorial Material
Materials Science, Multidisciplinary
Elvira De Giglio
Article
Biochemistry & Molecular Biology
Stefania Cometa, Maria Addolorata Bonifacio, Caterina Licini, Annalisa Bellissimo, Loris Pinto, Federico Baruzzi, Monica Mattioli-Belmonte, Elvira De Giglio
Summary: Hydrogel formulations represent a new frontier in customizable skin beauty and health, especially in wound dressing. This study focused on a new class of cellulose-derived, biodegradable hydrogel films incorporated with active compounds for dermatological issues, achieving promising results in terms of water uptake, cytocompatibility, skin permeation kinetics, and release properties.
Article
Pharmacology & Pharmacy
Adriana Trapani, Stefania Cometa, Elvira De Giglio, Filomena Corbo, Roberta Cassano, Maria Luisa Di Gioia, Sonia Trombino, Md Niamat Hossain, Sante Di Gioia, Giuseppe Trapani, Massimo Conese
Summary: A widely investigated approach to bypass the blood brain barrier is represented by the intranasal delivery of therapeutic agents exploiting the olfactory or trigeminal connections nose-brain. As for Parkinson's disease (PD), characterized by dopaminergic midbrain neurons degeneration, currently there is no disease modifying therapy. Although several bio-nanomaterials have been evaluated for encapsulation of neurotransmitter dopamine (DA) or dopaminergic drugs in order to restore the DA content in parkinsonian patients, the premature leakage of the therapeutic agent limits this approach. To tackle this drawback, we undertook a study where the active was linked to the polymeric backbone by a covalent bond. Thus, novel nanoparticles (NPs) based on N,O-Carboxymethylchitosan-DA amide conjugate (N,O-CMCS-DA) were prepared by the nanoprecipitation method and characterized from a technological view point, cytotoxicity and uptake by Olfactory Ensheating Cells (OECs). Thermogravimetric analysis showed high chemical stability of N,O-CMCS-DA NPs and X-ray photoelectron spectroscopy evidenced the presence of amide linkages on the NPs surface. MTT test indicated their cytocompatibility with OECs, while cytofluorimetry and fluorescent microscopy revealed the internalization of labelled N,O-CMCS-DA NPs by OECs, that was increased by the presence of mucin. Altogether, these findings seem promising for further development of N,O-CMCS-DA NPs for nose-to-brain delivery application in PD.
Article
Multidisciplinary Sciences
Maria A. Bonifacio, Andrea Cochis, Stefania Cometa, Annachiara Scalzone, Piergiorgio Gentile, Giuseppe Procino, Serena Milano, Alessandro C. Scalia, Lia Rimondini, Elvira De Giglio
Article
Multidisciplinary Sciences
Gabriella Leone, Danilo Vona, Elvira De Giglio, Maria Addolorata Bonifacio, Stefania Cometa, Saverio Fiore, Fabio Palumbo, Roberta Ragni, Gianluca M. Farinola, Stefania R. Cicco