期刊
SUPRAMOLECULAR CHEMISTRY
卷 23, 期 3-4, 页码 199-208出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10610278.2010.521833
关键词
self-assembly; host-guest systems; pericyclic reaction; enantioselectivity; chiral transfer
资金
- MEXT, Japan
- Chemistry Innovation through Cooperation of Science and Engineering
A self-assembled chiral coordination cage was prepared from triangular triazine-panel ligands and Pd(II) complexes with chiral diamine auxiliaries. The chiral environment of the cage is induced by the structural deformation of the triazine panels ascribed to the steric bulk of the substituents on the chiral auxiliaries. The chiral cage can accommodate a pair of two hydrophobic molecules to form a specific diastereomeric ternary complex. We succeeded in conducting unusual [2+2] and [2+4] asymmetric cycloadditions from the identical ternary complex including a maleimide derivative and aromatic compounds with 6-50% enantiomeric excess (ee). It is remarkable that the remote chirality on the auxiliaries is efficiently transmitted to the chiral orientation of achiral ligands, which define a chiral cavity, to induce up to 50% ee. The present strategy is widely applicable to cavity-directed asymmetric reactions and maintaining inherent properties of the cage.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据