Article
Microbiology
Eleonora Rolli, Axel de Zelicourt, Hanin Alzubaidy, Michael Karampelias, Sabiha Parween, Naganand Rayapuram, Baoda Han, Katja Froehlich, Aala A. Abulfaraj, Hanna Alhoraibi, Kiruthiga Mariappan, Cristina Andres-Barrao, Jean Colcombet, Heribert Hirt
Summary: Research findings suggest that the endophyte Enterobacter sp. SA187 can trigger immune responses in Arabidopsis, but only at high concentrations, possibly due to its ability to evade or suppress the plant defense system. Transcriptome analysis revealed that LYK4 plays a crucial role in balancing plant immunity and growth and development processes, affecting the plant's resistance to salt stress.
ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Chemistry, Applied
Yifan Jiang, Shanshan Du, Min Xu, Ting Yu, Baomei Zhou, Fanfan Yu, Hao Jiang, Lina Yang, Mengke Su, Honglin Liu
Summary: In-situ tracking of protein residue structural changes using two-dimensional correlation surface-enhanced Raman spectroscopy (2DC-SERS) allows for reliable discrimination between natural and artificially dyed edible bird's nest. A conceptual logical circuit using protein structure indicator and nitrite indicator enables automatic recognition of different bird's nest samples.
Article
Chemistry, Medicinal
Jonathan Moreno, Khalid Zoghebi, David Salehi, Lois Kim, Sorour Khayyatnejad Shoushtari, Rakesh K. Tiwari, Keykavous Parang
Summary: In this study, seven cell-penetrating peptides designed in our laboratory were evaluated for protein delivery. [WR](9) and [DipR](5) were found to be the most efficient peptides and were selected for further studies. Through confocal microscopy and FACS analysis, it was determined that [WR](9) and [DipR](5) were able to successfully deliver proteins.
Article
Multidisciplinary Sciences
Scott B. Biering, David L. Akey, Marcus P. Wong, W. Clay Brown, Nicholas T. N. Lo, Henry Puerta-Guardo, Francielle Tramontini Gomes de Sousa, Chunling Wang, Jamie R. Konwerski, Diego A. Espinosa, Nicholas J. Bockhaus, Dustin R. Glasner, Jeffrey Li, Sophie F. Blanc, Evan Y. Juan, Stephen J. Elledge, Michael J. Mina, P. Robert Beatty, Janet L. Smith, Eva Harris
Summary: The study revealed a protective mechanism by simultaneously antagonizing two domains of NS1, providing a mechanistic explanation for 2B7 protection against NS1-induced pathology and demonstrating the potential of this antibody to treat infections by multiple flaviviruses.
Article
Polymer Science
Thomke Belthle, Dan E. Demco, Andrij Pich
Summary: The internal nanostructure of stimuli-responsive microgels can be tailored by manipulating their chemical composition and morphology. In this study, microgels with phase-separated domains on a nanoscopic length scale were synthesized by copolymerization of N-vinylcaprolactam and amphiphilic-to-hydrophobic 1-vinyl-3-alkylimidazolium bromides. The synthesized microgels exhibited dual functionality for payload immobilization through electrostatic and hydrophobic interactions. The morphologies and properties of the microgels were systematically investigated using NMR spectroscopy and relaxometry.
Article
Biochemistry & Molecular Biology
Felix Nicolaus, Fatima Ibrahimi, Anne den Besten, Gunnar von Heijne
Summary: During the cotranslational insertion of membrane proteins mediated by SecYEG, both electrostatic and hydrophobic interactions involving sequence elements can impact the behavior of transmembrane helices, leading to delayed contact with the membrane.
Article
Thermodynamics
Yalun Li, Xinlei Gao, Xuning Feng, Dongsheng Ren, Yan Li, Junxian Hou, Yu Wu, Jiuyu Du, Languang Lu, Minggao Ouyang
Summary: This study comprehensively analyzes the changes in battery eruption temperature during thermal runaway after fast charging, and reveals the effects of lithium plating on gas production. The research contributes to a deeper understanding of the characteristics of thermal runaway after fast charging and provides valuable insights for the safe design and management of LIBs.
Article
Chemistry, Physical
Kun Zhang, Guohui Zhou, Timing Fang, Kun Jiang, Xiaomin Liu
Summary: The study used molecular dynamics simulations to investigate the behavior of surface active ionic liquid electrolytes near positive electrodes, revealing that with the increase of electrode surface charge density, anion [AOT](-) adopts a V-type conformation that is easier to replace latent voids. After a rapid charge/discharge cycle, more V-type anions appear in the optimized electrolyte.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Wenbo Zhang, Mingwei Liu, Robert L. Dupont, Kai Huang, Lanlan Yu, Shuli Liu, Xiaoguang Wang, Chenxuan Wang
Summary: This study focuses on the conservation of positively charged residue identity in the intermediate filament coiled-coil superfamily and identifies 10 distinct hotspots associated with pathogenic syndromes. The analysis reveals that the diversity of cationic residues is dependent on their distance from the hydrophobic domain, with nearby cationic residues showing higher conservation levels than those farther away.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Shahnaz Begum, Hasan Parvej, Ramkrishna Dalui, Swarnali Paul, Sanhita Maity, Nayim Sepay, Mohd Afzal, Umesh Chandra Halder
Summary: Insulin interacts with molecules in the bloodstream, with hydrophilic and hydrophobic molecules having different effects on its binding and structure. Hydrophilic molecules have a slightly higher binding affinity towards insulin, while hydrophobic molecules bind to a specific pocket on the insulin surface and strongly perturb its secondary structure.
Article
Multidisciplinary Sciences
Ruiqi Cai, Jingfeng Tang, Xing-Zhen Chen
Summary: The hydrophobicity of site 304 is crucial for maintaining PAC in a closed state at pH 7.5, while the hydrophilicity of site 307 significantly increases PAC activity when activated at acidic pH, indicating that 307 acts as an activation gate.
Article
Chemistry, Multidisciplinary
Motoki Nishimura, Yoshimasa Kawaguchi, Kakeru Kuroki, Yuna Nakagawa, Toshihiro Masuda, Takayuki Sakai, Kenichi Kawano, Hisaaki Hirose, Miki Imanishi, Tomoka Takatani-Nakase, Sergii Afonin, Anne S. Ulrich, Shiroh Futaki
Summary: Spatiotemporal structural alterations in cellular membranes play a crucial role in many vital processes. The N-terminal helical segment (EpN18) of Epsin-1 protein is essential in inducing positive membrane curvature. Understanding the structural features of EpN18 can help design effective tools for controlling membrane curvature.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Astronomy & Astrophysics
Kumiko Hori, Chris A. Jones, Arrate Antunano, Leigh N. Fletcher, Steven M. Tobias
Summary: Torsional waves that extend into the deep interior of Jupiter can modulate the outgoing heat flux and couple with Jupiter's weather layer to generate observed quasi-periodic oscillations in the cloud deck. These waves can be used to explore the interior structure of gas giants.
Article
Biochemistry & Molecular Biology
Max Staller, Eddie Ramirez, Sanjana R. Kotha, Alex S. Holehouse, Rohit Pappu, Barak A. Cohen
Summary: The study investigated acidic activation domains by designing thousands of variants, and found that strong activation domain activity requires a balance between the number of acidic residues, aromatic and leucine residues. A predictor was developed to identify and accurately predict acidic activation domains.
Article
Polymer Science
Stepans Kobenko, Didzis Dejus, Janis Jatnieks, Davis Pazars, Tatjana Glaskova-Kuzmina
Summary: This paper presents the results of structural integrity tests on two aircraft interior parts made from Ultem 9085 using fused deposition modeling (FDM). Numerical simulation and mechanical testing were conducted to analyze the strength and load-bearing capacity of the parts. The study found that increasing the width of the class divider effectively increased its bending stiffness, and the 3D-printed parts passed the most critical load test. The folding table, printed as a honeycomb structure, had an acceptable critical load of 900 N and showed potential for further optimization.